Browsing Temel Tıp Bilimleri Bölümü by Type "info:eu-repo/semantics/doctoralThesis"
Now showing items 61-80 of 164
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Hukuki ve Etik Yönleri ile Biyotıp Araştırmalarında Biyobankalar
(Sağlık Bilimleri Enstitüsü, 2013)Biobanks are the organizations where biological materials and associated personal information are collected, stored, processed and distributed in a particular systematic. Biobanks provide opportunity to easily obtain enough ... -
Hücre Kültüründe Aromataz/Sirtuin-1 Etkileşiminin miRNA İfade Düzeyine Olan Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Kartal, Y. Evaluation of the Relationship Between Aromatase/Sirtuin-1 Interaction and miRNA Expression in Human Neuroblastoma Cells, Hacettepe University Graduate School of Health Sciences Physiology Programme Doctor of ... -
Hüseyin Hulki Bey’in Eseri " Tabâbet-İ Hakikiye ve Mesâlik-İ Bâtıla-İ Tıbbiye " Nin Günümüz Türkçesine Kazandırılması ve Günümüz Tıp Anlayışıyla Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019-02-18)Mustafa Hayırlıdağ, Translating of Huseyin Hulki Bey's Work Which is "Real Art of Medicine and Practicies of Pseudo Medicine" to Today's Turkish and Its Examining with Contemporary Medical Approach, Hacettepe University ... -
Improvement of Germ Stem Cell Pool by Leptin Supplementation and Gene Editing for Male Infertility
(Sağlık Bilimleri Enstitüsü, 2020-06-12)Infertility affects up to 12-15% of sexually active couples, and male factors contribute about 30-55% of these cases. Infertility can be caused by injuries, genetic factors, exposure to toxicants, immune-suppressive and ... -
Investigating the Effects of Neurometabolic Disease-Causing Genes on Synapse Function in Drosophila melanogaster
(Sağlık Bilimleri Enstitüsü, 2022)Our group has identified several patients that harbor mutations in genes that hold the potential for being important players of synapse function, UNC79 and MBOAT7 being two of them. UNC79 is one of the accessory ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
Investıgatıon of The In Vıtro And In Vıvo Effects of Telomere-Targeted New Drug Candıdate Compounds on Dıfferent Cancer Cell Lınes
(Sağlık Bilimleri Enstitüsü, 2023)Cancer, characterized by its heterogeneity, metastatic character, and limited treatability, stands as a leading global cause of mortality. Cancer cells elongate their telomeres through the activity of the telomerase enzyme, ... -
İkinci Trimesterde Sağlıklı Ve Kromozomal Anomalili Gebeliklerde Fetal Nazal Kemik, Ense Katlantısı, Böbrek, Karaciğer, Barsak, Plasenta ve Maternal Uterus Kas Tabakasının B-Mod Histogram ve Shear Wave Elastogram Yöntemleri ile İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)B-mode ultrasonography is utilized in fetal screening of chromosomal abnormalities like Down Syndrome. Presence of soft markers such as hyperechogenic bowel, renal pelviectasis, hypoplastic nasal bone and increased nuchal ... -
İleri Yaşam Desteği Simülasyonunun Tıp Fakültesi Son Sınıf Öğrencilerinin Özyeterlik Algısına Etkisinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Evaluation Of The Effect Of Advanced Life Support Simulation On Final-Year Medical Students' Self-Efficacy Perceptions, Hacettepe University, Graduate School of Health Sciences, Medical Education Doctoral Thesis, Ankara, ... -
İnsan Granüloza Hücresi Mitokondriyon Fonksiyonu ile AMH ve Östrojen İlişkisi
(Tıp Fakültesi, 2021)Anti-Müllerian Hormone (AMH) and estrogen are essential hormones in human ovarian folliculogenesis. AMH and estrogen are produced by granulosa cells. It is known that mitochondria in human granulosa cells are important for ... -
İnsan Kaynaklı Kistik Ekinokokkozis'in Moleküler Epidemiyolojisi
(Sağlık Bilimleri Enstitüsü, 2017)Cystic Echinococcosis (CE) is a zoonotic disease caused by larval forms of parasites of the genus Echinococcus in humans. CE is one of the most common zoonotic diseases in the world, particularly in regions where the local ... -
İnsan Serum Bütirilkolinesterazının Olası Lipolitik Aktivitesi-Lipid Metabolizması ile İlişkisi.
(Sağlık Bilimleri Enstitüsü, 2021-01-21)Cholinesterases (AChE and BChE) terminate acetylcholine-induced neurotransmission at cholinergic synapses in muscle-nerve junctions. We previously showed BChE expression is regulated by essential fatty acids. The similarity ... -
İzlem Süresi İçerisinde Belirteçlerin Performanslarını Değerlendirmede Zamana Bağlı Roc Eğrisinin Kullanımı
(Sağlık Bilimleri Enstitüsü, 2015)The ROC (Receiver Operating Characteristic) method commonly used to evaluate the performance of biological markers which often used to help diagnosis and treatment. The performance of the marker should be evaluated with ... -
İzole Edilmiş Sıçan Pankreas Adacık Hücrelerine in Vitro Trombospondinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2013)Pancreas islet cells are very sensitive to hypoxic stress because of having small amount of anti-oxidant enzyme. Loss of islet cell viability due to hipoxic damage decreases success of transplantation. Islet- endothelial ... -
Kadmiyuma Maruz Kalan Sıçanlarda Davranışsal, Biyokimyasal ve Metabolomik Parametrelerde Gözlenen Değişikliklere Karvakrolün Etkisi
(Sağlık Bilimleri Enstitüsü, 24-05-22)Cadmium (Cd) is one of the toxic and carcinogenic heavy metals that can be found in the environment through activities such as industry and agriculture. Carvacrol (CAR) is a phenol found in various aromatic plants. CAR is ... -
Kalıtsal Metabolik Hastalıklarda Otofaji, Oksidatif Stres ve İnflamasyon İlişkisi
(Sağlık Bilimleri Enstitüsü, 2023-08)The complications such as epilepsy, cataract, hepatic failure, chronic renal disease may develop during the clinical follow-up of the patients with inherited metabolic diseases. The aim of this study is to investigate the ... -
Kan Kültüründen İzole Edilen Acinetobacter Baumannii ve Pseudomonas Aeruginosa Suşlarında Karbapenem Heterodirencinin Fenotipik ve Moleküler Yöntemlerle Araştırılması
(Tıp Fakültesi, 2023)Since heteroresistance (HR) was first detected in Haemophilus influenzae in 1947, it has been described in many bacterial species and against different antibiotic classes. Briefly, HR is defined as the presence of bacterial ... -
Kardiyovasküler Sistem Patofizyolojisinde Rol Alan Mikrornaların İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-12-12)The diseases and attendant complications of cardiovascular system consist of acute coronary syndrome, peripheral vascular disease and stroke that are distinct clinical manifestations yet stem from metabolically-originated ... -
Karyojenik Bakterilerin Dental Pulpa Hücresinde Oluşturduğu Oksidatif Stresin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)Caries-causing pathogenic microorganisms (cariogenic microorganisms) are the major source of pulpal inflammation and infection, and they cause the formation of reactive oxygen molecules (ROS) with the cell membrane components ... -
Kerevit Ganglia Transkriptomundaki Otopetrin Benzeri Bir Proton Kanalının Modellenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03-15)Crayfish is a frequently used model organism in neuroscience to understand the functions of ion channels and various neurotransmitters and neuromodulators. In silico modeling of the molecular structure of various proteins ...