2013-2014 Yılları Arasında Parenteral Nütrisyon Uygulanan Hastaların İzlemi

Abstract

ABSTRACT Ozturk, Z., Follow up of the patients who received parenteral nutrition between the years 2013-2014. Hacettepe University Faculty of Medicine, Thesis in Pediatrics. Ankara, 2015. Parenteral nutrition (PN) may be defined as to maintain the nutrition support intravenously in case oral or enteral nutrition is not sufficient. Although it is an efficient and safe treatment method, it has many metabolic complications depending on the content of PN mixture and many complications associated with venous access. In this study, the data of 178 patients who received 230 episodes of PN was investigated in terms of PN indications, content of PN mixture, PN duration and the body weight changes, complications, management and outcomes of the complications. This study revealed that PN was given to the patients most commonly with the diagnoses of hematological malignancies, surgical diseases of gastrointestinal system and to the patients who were undergone hematopoietic stem cell transplantation. It was found that body weight increased in about one third of the patients, the patients who gained weight received more energy than the ones who lost weight and most of targeted energy could be given via central venous catheters (CVCs) than peripheral venous accesses. Hypokalemia (40,4%), hypophosphatemia (39,8%), hypomagnesemia (40,9%), hypertriglyceridemia (35,6%), elevated liver enzymes (55,2%), CVC related thrombosis (4,1%), microbial growth in blood culture obtained from CVC (31,3%) were the striking complications. Most of the electrolyte and mineral imbalances were seen in the first three days. 56% of ursodeoxycolic acid-treated group of the patients with elevated liver enzymes, recovered with treatment without any adverse reaction. In conclusion, PN was given to the children effectively and safely, the efficiency could be increased with CVCs. Key words: childhood, follow up, complication, parenteral nutrition