Yayın tarihi için Sağlık Bilimleri Enstitüsü Tez Koleksiyonu listeleme
Toplam kayıt 87, listelenen: 21-40
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The Effect of Melatonın on Hıppo Sıgnallıng Pathway in Dental Pulp Stem Cells
(Sağlık Bilimleri Enstitüsü, 2020)Dental pulp stem cells (DPSCs) are heterogeneous multipotent adult stem cells with high capacity to differentiate to both neuronal and non-neuronal cell lineage. Hippo pathway regulates diverse cellular processes, including ... -
Geriatrik Vakalarda Yüksek Frekanslarda İzlenen Hava Kemik Aralığın Geniş Bant Timpanometri ve DPOAE Yanıtlarına Etkisi
(Sağlık Bilimleri Enstitüsü, 2020)Some anatomical, histological, and physiological changes occur in the external and middle ear depending on aging. In this study, we investigated the wideband tympanometry results of elderly people and different old age ... -
Fındık Alerjeninin Çapraz Kontaminasyon Yolaklarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2020-01-28)Cross-contamination is a major source of hidden allergens in foods and can occur at all food processing stages. The aim of this study was to investigate contamination pathways and the contamination levels of hazelnut ... -
Mezenkimal Kök Hücre Üretiminde İn Vitro Temelli Metabolomik ve Analizler
(Sağlık Bilimleri Enstitüsü, 2020-02-12)Karaağaç Akyol, T. Metabolomic And Analyzes In In-Vitro Based On The Production Of Mesenchimal Stem Cells, Hacettepe University Graduate School of Health Sciences Stem Cells Program Doctor of Philosophy Thesis, Ankara, ... -
Uyarılmış Pluripotent Kök Hücrelerin Araştırma Amaçlı Bankalanmasında Standardizasyon ve Kalite Süreci - Bir Uygulama Modeli: “Pedı-Stem”
(Sağlık Bilimleri Enstitüsü, 2020-06-18)Induced pluripotent stem cell (iPSC) is generated by genetic modification of any cell type of the body in laboratory conditions by transferring of embryonic stem cell-like pluripotent properties. iPSC is a cell model that ... -
Kemik İliği Yağ Tabakasından Elde Edilen Mezenkimal Kök Hücrelerin Karakterizasyonu ve Subkutan Yağ ve Kemik İliği Kökenli Mezenkimal Kök Hücreleri ile Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2020-09)Bone marrow adipose tissue (BMAT) has different properties than other adipose tissues. Recent studies have shown the effects of bone marrow adipose tissue on development / progression of acute myeloblastic leukemia (AML), ... -
Ergenlerin ve Ailelerinin Şiddete Yönelik İnanç ve Tutumlarinin Ergenlerin Şiddet Davranışlarına Etkileri
(Sağlık Bilimleri Enstitüsü, 2021)This study aims to create a set of data in order to find possible links between adolescents' violent behaviours and adolescents' and their families' beliefs and attitudes towards violence. Buss-Perry aggression scale (BPSS) ... -
Mezenkimal Kök Hücre Yaşlanmasında Nf-Κb/P65 ve Pknox2 Protein-Protein Etkileşimlerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2021)Mesenchymal stem cells undergo replicative senescence by cultivating in vitro and as the passage extends they lose their stem cell properties. Previous study of our group investigating proteomics of the co-immunoprecipitated ... -
Bayesian Networks for Omics Data Analysis in Hepatocellular Carcinoma Single-Cell Sequencing
(Sağlık Bilimleri Enstitüsü, 2021)Single cell multi omics techniques have shown an advancement in unrevealing complex diseases like cancer heterogeneity by providing multi-faceted insight into their individual cellular regulations. In this study, a machine ... -
The Perceptions of Healthcare Professionals Serving Migrant, Refugee and Asylum Seekers in the Primary Healthcare Centers of Hatay, Şanlıurfa, Gaziantep and İzmir About Healthcare Provision, and Their Level of Burnout
(Halk Sağlığı Enstitüsü, 2021)Objective: The purpose of this study is to investigate the level of burnout and perceptions of health professionals serving in primary healthcare centers in four provinces in Turkey, namely Gaziantep, Hatay, İzmir, ... -
Hematopoetik Kök Hücre Gen Tedavi Kültür Koşulları ve Engraftman Optimizasyonu
(Sağlık Bilimleri Enstitüsü, 2021)RAG2 severe combined immunodeficiency (SCID) is a rare, inherited primary immunodeficiency (PID), characterized by a T-/B-/NK+ phenotype and is treated with hematopoietic stem cell (HSC) transplantation. When no suitable ... -
Dört Farklı Kansere Ait Transkriptom Verisinin In Sılıco Karşılaştırılması ve Pankreas Kanserine Özgü Biyobelirteç Adaylarının Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2021-02-23)Pancreatic cancer is the 11th most common cancer worldwide. Five-year survival of lung, colon and stomach cancers, which are the top three in cancer related deaths, are 19%, 65% and 20%, respectively. Although pancreatic ... -
Methionine Metabolism in Human Fetal, Adult and Cancer Stem Cells
(Sağlık Bilimleri Enstitüsü, 2021-08-09)Methionine is an essential amino acid critical in protein synthesis and methylation reactions. In this thesis, it is aimed to determine the effect of methionine on different human stem cell groups. Mesenchymal stem cells ... -
Prokainamidin Farmasötik Preparattan ve Plazmadan Yeşil Hplc vle Analizi
(Sağlık Bilimleri Enstitüsü, 2022)In drug analysis, using non-hazardous solvents instead of these solvents harmful to the human and environment is a greening strategy to protect analyst and environmental health and minimize produced toxic waste budged. ... -
Arteria Iliaca Interna’nın Dallanma Paterni ve Varyasyonları ile Klinik Etkileri Arasındaki İlişkiler
(Sağlık Bilimleri Enstitüsü, 2022)SELCUK, I., Variations and branching pattern of internal iliac artery: Clinical applications. Hacettepe University Graduate School of Health Sciences Anatomy Department, Anatomy Doctor of Philosophy Thesis, Ankara, 2022. ... -
ADAM19, FAM13A, IREB2 Genleri Yaygın Varyantlarının KOAH Yatkınlığı ve Şiddeti ile İlişkisi
(Sağlık Bilimleri Enstitüsü, 2022)Chronic obstructive pulmonary disease (COPD) is a heterogenous disease characterized by persistent airway limitation caused by both genetic predisposition and environmental factors. In this study, we aimed to investigate ... -
Tıp Fakültesi Son Sınıf Öğrencilerinin Hastane Öncesi ve Acil Servislerde Travmalı Hastaya Yaklaşımının Senaryo Temelli Simülasyonla Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)Gülbaş, H., Evaluation of Senior Medical Students’ Approaches to Trauma Patients in Prehospital and Emergency Services Using Scenario Based Simulation. Hacettepe University Institute of Health Sciences Simulation Program ... -
Türkiye Taşkömürü Kurumu'nda Çalışan Tahlisiye Personelinin Tahlisiye Eğitim ve Görevleri İle İlgili Bazı Özelliklerinin ve İkincil Travmatik Stres Düzeylerinin Değerlendirilmesi Zonguldak-Bartın, 2020
(Sağlık Bilimleri Enstitüsü, 2022)In this study, it was aimed to evaluate some characteristics of mine rescue training and duties of the employees assigned as mine rescuers in Turkish Hard Coal Enterprise and secondary traumatic stress levels of rescuers ... -
Apc Mutant Fare İntestinal Organoidlerinde Wnt Yolak Modülasyonunun Kök Hücreler Üzerine Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2022)One of the most important causes of colorectal cancer development is mutations of genes involved in the WNT signaling pathway. In the vast majority of cases, APC tumor suppressor gene mutations, which act as negative ... -
Yapay Öğrenme Bazlı Hesaplamalı Modelleme İle Geniş Çaplı Kanser Hücre Hattı İlaç Yanıt Tahmini
(Sağlık Bilimleri Enstitüsü, 2022)Assessing the best treatment option specifically for each patient is the main goal of precision medicine. The patients with the same diagnosis may display varying sensitivity to the applied treatment due to genetic ...