Çocukluk Çağı Behçet Hastalığı Vakalarının Retrospektif Değerlendirilmesi

Abstract

Behçet disease is a multisystemic vasculitis characterized by oral ulcers accompanied with skin and mucosa manifestations. Turkey is one of the regions where disease is more common. There is not enough demographic data in literature about Behçet disease so in our country there is need for pediatric Behçet case reports. In this study data of patients, who were diagnosed as Behçet disease and treated in Hacettepe University Ihsan Dogramaci Pediatric Hospital Pediatric Nephrology and Rheumatology Departments between 01th January 1980 and 01th January 2013, collected by retrospective search. Thirty four patients (18 male, 16 female) were included in the study. We used criteria of the International Study Group for the diagnosis of Behçet disease. Any patient with recurrent oral ulcers and 2 of other criterion (genital ulcers, other skin lesions, uveitis, pathergy) was included the study. Medial age at first admission was 11,18±3,34 and most frequent first complaint was oral apthae (97%). In 15% of patients there was family history. Those patients with vasculitis or any important organ involvement were treated with pulse steroid and immunosuppressive drugs and sometimes when it is required with anticoagulants. Our results show that although Behçet disease is rare in childhood than adulthood clinical signs are similar and there is correlation between family history and frequency of disease which may sign that there are some genetic factors in disease development.