Continuous activation of HER2 leads to the deregulation of various biological responses such as cell proliferation, survival, and migration, and tumor growth. eEF2K is a protein kinase involved in the regulation of protein ...

Cancer cells are proliferate rapidly and uncontrolled. Chemotherapeutics such as vinorelbine and colchicine affect the cell cycle and DNA synthesis mechanism; they causes cells to be kept in the G2 / M phase by preventing ...

Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ...

The tumor microenvironment (TME) contains cancer-associated fibroblasts (CAFs) and their tumor-supportive role helps to build an environment in favor of cancer cell progression. Recent researches have revealed that targeting ...

Pancreatic cancer is an aggressive malignancy with a poor prognosis. Early diagnosis and application of tumor-specific treatment are very important in pancreatic cancer. Therefore, new biomarkers are needed in the diagnosis ...

Çakan, E., Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-Like Receptors (TLR) on Regulation of the Central B Cell Tolerance Checkpoint, Hacettepe University Graduate School Health Sciences Program ...