Browsing Biyomühendislik Bölümü Tez Koleksiyonu by Issue Date
Now showing items 41-60 of 96
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MEME KANSERİ HÜCRELERİNE mTOR ANTİSENS OLİGONÜKLEOTİTLERİNİ HEDEFLEYECEK TRANSFERRİN KAPLANMIŞ ALTIN NANOPARTİKÜLLERİN TASARIMI SENTEZİ VE UYGULANMASI
(Fen Bilimleri Enstitüsü, 2017-10)Breast cancer is the most frequent cancer in women. The type and molecular characteristics of breast cancer determines prognosis and helps design effective therapy regimes. mTOR, the mammalian target of Rapamycin is one ... -
Enzimatik Tabanlı Bakteriyel Biyosensör
(Fen Bilimleri Enstitüsü, 2018)The objective of the project is to provide colorimetric bacteria detection. Creating colorimetric biosensors gives us an opportunity to get more precise data. Biosensors have advantages over traditional ones such as low ... -
Yüzeylerin Titanyum Nanoçubuklar Ve Onların Altın/Gümüş İle Modifiye Formları İle Nanodesenlenmesi Ve Farklı Alanlarda Kullanılabilirliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)Nanoscience and nanotechnology transform the material science into a wide range, providing the continuous development of new nanostructured materials. A comprehensive examination of physicochemical phenomena at the nanoscale ... -
Poliüretan Tabanlı Kemik Yapıştırıcısı Formülasyonları
(Fen Bilimleri Enstitüsü, 2018)Millions of people are in need of bone injury treatment for many reasons such as traffic accidents, daily injuries, sports injuries. For the stabilization of bone fractures in the health field; plastering, external ... -
Dejeneratif Kıkırdak Hasarlarına Yönelik Enjekte Edilebilir Hidrojel Sistemlerinin Geliştirilmesi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2018)Cartilage degeneration is a pathology that develops over time, beginning with the softening of the cartilaginous gland and then completely disappearing. It may be due to trauma, as well as diseases such as osteoarthritis, ... -
Doku Mühendisliğinde Malzemeye Ve Hücresel Özelliklere Ait İmgelerin Görüntü İşleme Teknikleri İle Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2018)Image processing techniques are frequently used to obtain quantitative information from images of various imaging techniques. Image analysis in tissue engineering and cell biology is a time-consuming and specialized process. ... -
Sklera Hasarlarının Rekonstruksiyonunda Otojenik, Allojenik Ve Zenojenik Greftlerin Karşılaştırılması: Yeni Bir Otolog Yaklaşım “Trombositten Zengin Fibrin Membran”
(Fen Bilimleri Enstitüsü, 2018)The purpose of the presented thesis was to compare the effects of xenogenic, allogenic and autogenic graft materials on scleral healing in the repair of scleral tissue damage. For this purpose, scleral tissue damage model ... -
Development Of Beta-Tricalcium Phosphate Based Injectable Synthetic Bone Graft Materials
(Fen Bilimleri Enstitüsü, 2018)As the global population ages, the number of patients suffering from bone tissue loss due to trauma, degenerative diseases, or surgical intervention increases. To meet the demand for bone graft materials, synthetic substitutes ... -
Aljinat-Halloysit Biyokompozitlere Ciprofloxacin Yüklenmesi, Salımı Ve Adsorpsiyonunun İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)In this thesis, biocomposite HLT-ALJ is loaded with ciprofloxacin (CIP) antibiotic by adding halloysite (HLT) and alginate (ALJ) HLT. HLT nanotubes are naturally occurring clay minerals. HLT located between the layers and ... -
Kütle Spektrometrisi Uygulamalarında Fosfopeptitlerin Hassas Tayini İçin Yeni Stratejilerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018)Most of the proteins may at some time be phosphorylated on serine, threonine or tyrosine aminoacids when they perform a certain function. Phosphoprotein is protein that contain phosphate group in structure. The smaller ... -
Serpınb1 Ve Serpınb2 Proteaz İnhibitörlerinin Bronş Epitel Hücrelerindeki İnflamatuvar Cevaptaki Rolü
(Fen Bilimleri Enstitüsü, 2018)Asthma is a serious health problem affecting nearly 300 million people worldwide. Asthma frequency varies based on countries and even based on regions of same country. For example, Australia and New Zealand have a frequency ... -
Salinomisin ve BnHAp Yüklü Doku İskelelerinin Antikanserojen ve Antibakteriyel Etkinliğinin Araştırılması
(Fen Bilimleri Enstitüsü, 2018)In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ... -
Bor İçeren Nano Hidroksiapatit Kompozitlerin Kemik Hücrelerindeki Moleküler Etki Mekanizmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2018)The structure of the bone and the self-renewal capacity are damaged by metabolic diseases and damages. The trace elements and hydroxyapatite crystals in the bone are important in the development of biomaterials to support ... -
Preparation and Investigation of Ph-Sensitive Hydrogels/ Nanopartıcles for Drug Delivery
(Fen Bilimleri Enstitüsü, 2018)Oral administration of the drugs is considered as one of the most convenient and comfortable routes. However, an effective oral delivery of insulin still remains a challenging and elusive goal, due to bioavailability ... -
Tendon Doku Mühendisliği İçin Poli(Gliserol-Sebakat) (Pgs) Tabanlı Elastomerik Matrisler
(Fen Bilimleri Enstitüsü, 2018)Tendon have an important function in transferring force from muscle to bone. Tendon metabolism can change the structural properties according to the applied mechanical forces.. The natural healing mechanism after the ... -
SALİNOMİSİN ve BnHAp YÜKLÜ DOKU İSKELELERİNİN ANTİKANSEROJEN ve ANTİBAKTERİYEL ETKİNLİĞİNİN ARAŞTIRILMASI
(Fen Bilimleri Enstitüsü, 2018)In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ... -
CİLT YENİLENMESİ İÇİN YENİ BİR FİBRİN MATRİS OLUŞTURULMASI, KİMYASAL/FİZİKSEL ÖZELLİKLERİ VE DOKU İSKELESİ OLUŞTURMA POTANSİYELİ AÇISINDAN İNCELENMESİ
(Fen Bilimleri Enstitüsü, 2018-01)There are a considerable amount of wound dressings, fillers and tissue engineered products for the treatment of skin damages, burns, diabetic wounds or skin aging. These products sometimes lead to adverse reactions like ... -
Amoksisilin Baskılanmış Yüzey Plazmon Rezonans Nanosensörler
(Fen Bilimleri Enstitüsü, 2018-01-05)Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections. They may either kill or inhibit the growth of bacteria. AMOXicillin (AMOX) is also an antibiotic for the treatment ... -
SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION
(Fen Bilimleri Enstitüsü, 2018-02)ABSTRACT SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION Galiya RAZYM Master of Science, Department of Bioengineering Supervisor: Prof. Dr. Handan Yavuz Alagöz January 2018, 65 pages ... -
Manyetik Silika Bazlı Borat Afinite Kromatografisi Sorbentlerinin Sentezi Ve Kromatografik Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2018-06)In this study, β-nicotinamide adenine dinucleotide (β-NAD) was molecularly imprinted onto plain and magnetic silica microspheres in the monodisperse-porous form, by core-shell polymerization method. For this purpose, ...