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Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)
Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ...
Cancer Burden In Four Countries Of The Middle East Cancer Consortium (Cyprus; Jordan; Israel; Izmir (Turkey)) With Comparison To The United States Surveillance; Epidemiology And End Results Program
(Elsevier Sci Ltd, 2016)
It is important that population-based cancer registries provide accurate and reliable data for public health purposes. These data are essential data for planning of cancer control and prevention. In this study, we examined ...
Higher Ki67 Expression Is Associates With Unfavorable Prognostic Factors and Shorter Survival in Breast Cancer
(Asian Pacific Organization Cancer Prevention, 2014)
Background: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, ...
Impact Of Acetylsalicylic Acid On The Clinicopathological Characteristics And Prognosis Of Patients With Invasive Breast Cancer
(Karger, 2014)
Background: The impact of acetylsalicylic acid (ASA) on the clinicopathological characteristics of breast cancer has not yet been elucidated in detail; we therefore aimed to investigate the effects of ASA on the ...
Good Outcomes Of Patients With Stage Ib Endometrial Cancer With Surgery Alone
(Asian Pacific Organization Cancer Prevention, 2014)
Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/radiotherapy ...
Impact Of Adjuvant Chemoradiotherapy For Rectal Cancer On The Long-Term Quality Of Life And Late Side Effects: A Multicentric Clinical Evaluation By The Turkish Oncology Group
(Asian Pacific Organization Cancer Prevention, 2012)
Aim: Although preoperative chemoradiatherapy (CRT) has proven its benefits in terms of decreased toxicity, there is still a considerable amount of cases that do not receive postoperative CRT. Oncologists at different ...
Ubiquitination And Regulation Of Aurka Identifies A Hypoxia-Independent E3 Ligase Activity Of Vhl
(Nature Publishing Group, 2017)
The hypoxia-regulated tumor-suppressor von Hippel-Lindau (VHL) is an E3 ligase that recognizes its substrates as part of an oxygen-dependent prolyl hydroxylase (PHD) reaction, with hypoxia-inducible factor α (HIFα) being ...
Cancer Trends and Incidence and Mortality Patterns in Turkey
(Oxford Univ Press, 2011)
Cancer incidence and mortality rates have been increasing in Turkey as most of the developing countries. Besides socioeconomic factors, one of the most prominent attributes of developing countries is the dissimilarity of ...
Effect of Zoledronic Acid on Rats' Tissue Sdf-1 Expression
(Akad Doktorlar Yayınevi, 2016)
Zoledronic acid has been shown to inhibit cancer cell proliferation, metastasis and induce cancer cell apoptosis. Stromal Derived Factor-1 (SDF-1) is a chemokine that has been reported to be expressed markedly high in the ...