• Discovery of Biomarkers In Rare Diseases: Innovative Approaches By Predictive and Personalized Medicine 

      Gülbakan, Basri; Özgül, Rıza Köksal; Yüzbaşıoğlu, Ayşe; Kohl, Matthias; Deigner, Hans-Peter; Özgüç, Meral (Springer, 2016)
      There are more than 8000 rare diseases (RDs) that affect >5 % of the world’s population. Many of the RDs have no effective treatment and lack of knowledge creates delayed diagnosis making management difficult. The emerging ...
    • Prognostic Significance of Notch1 and Fbxw7 Mutations in Pediatric T-All 

      Erbilgin, Yücel; Sayitoğlu, Müge; Hatırnaz, Özden; Doğru, Ömer; Akçay, Arzu; Tüysüz, Gülen; Celkan, Tiraje; Aydoğan, Gönül; Şalcıoğlu, Zafer; Timur, Çetin; Yüksek Soycan, Lebriz; Üre, Ümit; Anak, Sema; Ağaoğlu, Leyla; Devecioğlu, Ömer; Yıldız, İnci; Özbek, Uğur (Hindawi Ltd, 2010)
      The NOTCH signaling pathway plays important role in the development of multicellular organisms, as it regulates cell proliferation, survival, and differentiation. In adults, it is essential for the T- or B-lymphocyte lineage ...