Ara
Toplam kayıt 337, listelenen: 291-300
Clinical Long-Time Course, Novel Mutations And Genotype-Phenotype Correlation In A Cohort Of 27 Families With Pomt1-Related Disorders
(2019)
Background The protein O-mannosyltransferase 1, encoded by the POMT1 gene, is a key enzyme in the glycosylation of α-dystroglycan. POMT1–related disorders belong to the group of dystroglycanopathies characterized by a ...
Impairment Of Lipophagy By Pnpla1 Mutations Causes Lipid Droplet Accumulation In Primary Fibroblasts Of Autosomal Recessive Congenital Ichthyosis Patients
(2019)
Background: Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of epidermal keratinization disorders. One of the disease-associated proteins, patatin-like phospholipase domain-containing protein-1 (PNPLA1), plays ...
Epidermal Growth Factor Enhances Spinal Fusion: Posterolateral Lumbar Fusion Model On Rats
(2019)
Objective The aim of this study was to investigate the effects of human recombinant epidermal growth factor (EGF) on posterolateral lumbar fusion in a rat model. Methods 36 male Sprague Dawley rats underwent posterolateral ...
Outcome Of 102 Patients Under 5 Years Of Age With Hodgkin Lymphoma
(2019)
Background. Hodgkin's lymphoma (HL) is one of the most curable pediatric cancers, however it is rare among children under five years of age and prognostic factors for survival rate are still unknown due to low frequency ...
Class I Histone Deacetylase Inhibition By Aryl Butenoic Acid Derivatives: In Silico And In Vitro Studies
(2019)
Histone deacetylases (HDAC) are evolutionary conserved enzymes, which catalyze removal of acetyl groups from histone and non-histone proteins, therefore, control multiple biological processes. Inhibition of their activities ...
Investigations Of Microtubule-Associated Protein 2 Gene Expression In Spinal Muscular Atrophy
(2019)
Aim: Spinal muscular atrophy (SMA) is a devastating genetic disease in childhood andff is caused by the absence of functional survival motor neuron (SMN) protein, which leads to impairments of the cytoskeleton, especially ...
Effects Of Propranolol And Paclitaxel On Angiogenesis In Breast Cancer Cell Lines
(2019)
Purpose: The aim of this study was to investigate the effect of propranolol (PR), which is used in infantile hemangiomas, and paclitaxel (PX), which is widely used as an chemotherapeutic agent, on cancer cells. Materials ...
Effects Of Clozapine And Haloperidol Treatment On Plasma Concentrations Of Androgen Hormones And Androgendependent Organ Changes In Rats
(2019)
OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of ...
The Effectiveness Of Traditional Basic Life Support Training And Alternative Technology-Enhanced Methods In High Schools
(2019)
Background: Implementation of resuscitation training in school programs is a promising approach to improve rates of cardiopulmonary resuscitation use by trained bystanders. Unfortunately, theoretical cardiopulmonary ...