Başlık için Temel Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 459, listelenen: 300-319
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Mutation Analysis In Turkish Phenylketonuria Patients
(British Med Journal Publ Group, 1993)Forty-four classical PKU patients have been screened for various mutations. The newly identified IVS 10 splicing mutation was found in 32% of the mutant alleles and comprises 74.5% of the mutations that could be typed: ... -
Mutation Analysis Of Nphs1 In A Worldwide Cohort Of Congenital Nephrotic Syndrome Patients
(Karger, 2012)Background: Congenital nephrotic syndrome (CNS) is defined as nephrotic syndrome that manifests within the first 3 months of life. Mutations in the NPHS1 gene encoding nephrin, are a major cause for CNS. Currently, more ... -
Mutation In Tor1Aip1 Encoding Lap1B In A Form Of Muscular Dystrophy: A Novel Gene Related To Nuclear Envelopathies
(Pergamon-Elsevier Science Ltd, 2014)We performed genome-wide homozygosity mapping and mapped a novel myopathic phenotype to chromosomal region 1q25 in a consanguineous family with three affected individuals manifesting proximal and distal weakness and atrophy, ... -
Mutations In Cgi-58, The Gene Encoding A New Protein Of The Esterase/Lipase/Thioesterase Subfamily, In Chanarin-Dorfman Syndrome
(Cell Press, 2001)Chanarin-Dorfman syndrome (CDS) is a rare autosomal recessive form of nonbullous congenital ichthyosiform erythroderma (NCIE) that is characterized by the presence of intracellular lipid droplets in most tissues. We ... -
Mutations Of The Cftr Gene In Turkish Patients With Congenital Bilateral Absence Of The Vas Deferens
(Oxford Univ Press, 2004)BACKGROUND: Mutations of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) can cause congenital bilateral absence of the vas deferens (CBAVD) as a primarily genital form of cystic fibrosis. The spectrum and ... -
Neisseria Meningitidis W135, Turkey
(2004)We describe the first case of Neisseria meningitidis W135 meningitis in Turkey. The strain was genotypically unrelated to the clone (W)ET-37, isolated from Hajj pilgrims in 2000. -
Neuroprotective Effect Of Magnesium Sulfate And Dexamethasone On Intrauterine Ischemia In The Fetal Rat Brain: Ultrastructural Evaluation
(Turkish Neurosurgical Soc, 2013)AIM: The aim of this study was to investigate the neuroprotective effect of magnesium sulfate and dexamethasone on oxidative damage in intrauterine ischemia. MATERIAL and METHODS: In this study, 19-day pregnant rats were ... -
Neuroprotective Effects Of Quetiapine On Neuronal Apoptosis Following Experimental Transient Focal Cerebral Ischemia In Rats
(2013)Objective This study was undertaken in the belief that the atypical antipsychotic drug quetiapine could prevent apoptosis in the penumbra region following ischemia, taking into account findings that show 5-hydroxytryptamine-2 ... -
Neuroprotective Effects Of Thymoquinone Against Spinal Cord Ischemia-Reperfusion Injury By Attenuation Of Inflammation, Oxidative Stress, And Apoptosis
(Amer Assoc Neurological Surgeons, 2016)OBJECTIVE lschemia-reperfusion (I/R) injury of the spinal cord following thoracoabdominal aortic surgery remains the most devastating complication, with a life-changing impact on the patient. Thymoquinone (TQ), the main ... -
New, Newer, Newest Human Polyomaviruses: How Far?
(Ankara Microbiology Soc, 2013)Polyomaviruses, classified in Polyomaviridae family, are non-enveloped small (40-45 nm) viruses with icosahedral symmetry and circular double-stranded DNA genome. Polyomaviruses can infect a variety of vertebrates including ... -
Non-Hacek Gram-Negative Bacillus Endocarditis
(2019)Patients and methods: Retrospective analysis of clinical data using 26 diagnosed non-HACEK Gram-negative infective endocarditis cases from nine hospitals in Turkey. Results: Mean age of patients was 53 (28–84) years, with ... -
Occlusal Caries Depth Measurements Obtained By Five Different Imaging Modalities
(Springer, 2011)The study aimed to assess the accuracy and reproducibility of occlusal caries depth measurements obtained from different imaging modalities. The study comprised 21 human mandibular molar teeth with occlusal caries. Teeth ... -
Outcome Of 102 Patients Under 5 Years Of Age With Hodgkin Lymphoma
(2019)Background. Hodgkin's lymphoma (HL) is one of the most curable pediatric cancers, however it is rare among children under five years of age and prognostic factors for survival rate are still unknown due to low frequency ... -
Oxa-11, An Extended-Spectrum Variant Of Oxa-10 (Pse-2) Beta-Lactamase From Pseudomonas-Aeruginosa
(Amer Soc Microbiology, 1993)Pseudomonas aeruginosa ABD, which was isolated in October 1991 from blood cultures of a burn patient in Turkey, was resistant to cephalosporins, particularly ceftazidime (MIC, 512 mug/ml), penicillins, aztreonam, and ... -
Oxa-15, An Extended-Spectrum Variant Of Oxa-2 Beta-Lactamase, Isolated From A Pseudomonas Aeruginosa Strain
(Amer Soc Microbiology, 1997)Pseudomonas aeruginosa AH, isolated in Ankara, Turkey, was highly resistant to ceftazidime (MIC, 128 mu g/ml) and produced a beta-lactamase that gave a doublet of bands at pIs 8.7 and 8.9, beta-Lactamase production was ... -
Oxa-16, A Further Extended-Spectrum Variant Of Oxa-10 Beta-Lactamase, From Two Pseudomonas Aeruginosa Isolates
(Amer Soc Microbiology, 1998)Two extended-spectrum mutants of the class D beta-lactamase OXA-10 (PSE-2) from Pseudomonas aeruginosa isolates obtained in Ankara, Turkey, were described previously and were designated OXA-11 and -14. P. aeruginosa 906 ... -
Oxa-17, A Further Extended-Spectrum Variant Of Oxa-10 Beta-Lactamase, Isolated From Pseudomonas Aeruginosa
(Amer Soc Microbiology, 1999)Pseudomonas aeruginosa isolates 871 and 873 were isolated at Hacettepe University Hospital in Ankara and were highly resistant to ceftazidime (MIC, 128 mu g/ml). Each produced three beta-lactamases, with pIs of 5.3, 6.1, ... -
Oxidative Effects Of Selenite On Rat Ventricular Contractility And Ca Movements
(Elsevier Science Bv, 1996)Objective: The study aimed at characterizing the effects of selenite, known for its reactivity with thiols, on cardiac contractility and excitation-contraction coupling. Methods: The inotropic effects of selenite were ...