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Economic Burden of Pneumococcal Infections in Children Under 5Years of Age
(Taylor & Francis Inc, 2018)
The present study aimed to determine the cost of childhood pneumococcal infections under 5years of age and to provide further data for future health economy studies. Electronic medical records of children diagnosed with ...
Functional Analysis Of Naturally Occurring Dclre1C Mutations And Correlation With The Clinical Phenotype Of Artemis Deficiency
(Mosby-Elsevier, 2015)
Background: The endonuclease ARTEMIS, which is encoded by the DCLRE1C gene, is a component of the nonhomologous end-joining pathway and participates in hairpin opening during the V(D)J recombination process and repair of ...
Hematopoietic Stem Cell Transplantation Using Preimplantation Genetic Diagnosis And Human Leukocyte Antigen Typing For Human Leukocyte Antigen-Matched Sibling Donor: A Turkish Multicenter Study
(Elsevier Science Inc, 2017)
Preimplantation genetic diagnosis involves the diagnosis of a genetic disorder in embryos obtained through in vitro fertilization, selection of healthy embryos, and transfer of the embryos to the mother's uterus. Preimplantation ...
Interleukin (Il)-12 And Il-23 Are Key Cytokines For Immunity Against Salmonella In Humans
(Univ Chicago Press, 2004)
Patients with inherited deficiency of the interleukin (IL)-12/IL-23-interferon (IFN)-gamma axis show increased susceptibility to invasive disease caused by the intramacrophage pathogens salmonellae and mycobacteria. We ...
Distribution Of Streptococcus Pneumoniae Serotypes That Cause Parapneumonic Empyema In Turkey
(Amer Soc Microbiology, 2013)
Streptococcus pneumoniae is the most common etiological cause of complicated pneumonia, including empyema. In this study, we investigated the serotypes of S. pneumoniae that cause empyema in children. One hundred fifty-six ...
Human Procaspase-1 Variants With Decreased Enzymatic Activity Are Associated With Febrile Episodes And May Contribute To Inflammation Via Rip2 And Nf-Kb Signaling
(Amer Assoc Immunologists, 2014)
The proinflammatory enzyme caspase-1 plays an important role in the innate immune system and is involved in a variety of inflammatory conditions. Rare naturally occurring human variants of the caspase-1 gene (CASP1) lead ...
International Consensus on (Icon) Pediatric Asthma
(Wiley, 2012)
Asthma is the most common chronic lower respiratory disease in childhood throughout the world. Several guidelines and/or consensus documents are available to support medical decisions on pediatric asthma. Although there ...
Differential Biological Role Of Cd3 Chains Revealed By Human Immunodeficiencies
(Amer Assoc Immunologists, 2007)
The biological role in vivo of the homologous CD3 gamma and delta invariant chains within the human TCR/CD3 complex is a matter of debate, as murine models do not recapitulate human immunodeficiencies. We have characterized, ...
The Effect of Granulocyte Colony-Stimulating Factor on Immune-Modulatory Cytokines in the Bone Marrow Microenvironment and Mesenchymal Stem Cells of Healthy Donors
(Elsevier Science Inc, 2015)
Granulocyte colony stimulating factor (G-CSF) is sometimes administered to donors before bone marrow (BM) harvest. G-CSF primed (G-BM) and unprimed BM (U-BM) derived mesenchymal stem cells (MSC) were obtained from 16 healthy ...
Allergic Rhinitis And Its Impact On Asthma (Aria): Achievements In 10 Years And Future Needs
(Mosby-Elsevier, 2012)
Allergic rhinitis (AR) and asthma represent global health problems for all age groups. Asthma and rhinitis frequently coexist in the same subjects. Allergic Rhinitis and its Impact on Asthma (ARIA) was initiated during a ...