Konu "Hematology" için Dahili Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 67, listelenen: 1-20
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A Complex Splicing Defect Associated With Homozygous Ankyrin-Deficient Hereditary Spherocytosis
(Amer Soc Hematology, 2007)Defects in erythrocyte ankyrin are the most common cause of typical, dominant hereditary spherocytosis (HS). Detection of ankyrin gene mutations has been complicated by allelic heterogeneity, large gene size, frequent de ... -
A Novel Approach to Treatment in Childhood Acute Myeloblastic Leukemia and Myelodysplastic Syndrome with High-Dose Methylprednisolone As a Differentiation- and Apoptosis-Inducing Agent of Myeloid Leukemic Cells
(Galenos Yayıncılık, 2010)Differentiation-inducing therapy with all-trans retinoic acid significantly improved the outcome in children with acute promyelocytic leukemia (APL). Therefore, use of agents that induce differentiation of leukemic cells ... -
A Phase II, Multicenter, Single-Arm Study to Evaluate the Safety and Efficacy of Deferasirox after Hematopoietic Stem Cell Transplantation in Children with Beta-Thalassemia Major
(Elsevier Science Inc, 2018)We conducted a prospective, phase II, multicenter, single-arm study to evaluate the efficacy and safety of deferasirox in patients age >2 to <18 years with beta-thalassemia major (TM) who underwent hematopoietic stem cell ... -
Allogeneic Hematopoietic Sct For Adults Aml Using I.V. Bu In The Conditioning Regimen: Outcomes And Risk Factors For The Occurrence Of Hepatic Sinusoidal Obstructive Syndrome
(Nature Publishing Group, 2014)I.v. BU is frequently used in the conditioning regimen prior to allogeneic hematopoietic SCT (allo-HSCT); however, overall outcomes, incidence of hepatic sinusoidal obstructive syndrome (SOS) and its risk factors are not ... -
Alpha-Synuclein Aggregation Induced By Brief Ischemia Negatively Impacts Neuronal Survival in Vivo: A Study in [A30P] Alpha-Synuclein Transgenic Mouse
(Sage Publications Inc, 2011)Alpha-synuclein oligomerization and aggregation are considered to have a role in the pathogenesis of neurodegenerative diseases. However, despite numerous in vitro studies, the impact of aggregates in the intact brain is ... -
An Unusual Presentation of Pediatric Acute Lymphoblastic Leukemia with Parotid Gland Involvement and Dactylitis
(Aves Yayincilik, 2010)Mumps infection during the course of childhood acute lymphoblastic leukemia (ALL) treatment has been reported to have a mild course and this was related to the intrinsic low cytopathological effect of the virus, contrasting ... -
Atraumatic Osteonecrosis After Estrogen Replacement Therapy Associated with Low Protein S Level in a Patient with Turner Syndrome
(Sage Publications Inc, 2010)Atraumatic osteonecrosis has been associated with a variety of clinical conditions including corticosteroid usage, alcoholism, infections, hyperbaric events, storage disorders, marrow-infiltrating diseases, coagulation ... -
Autoimmune Hemolytic Anemia and Giant Cell Hepatitis: Report of Three Infants
(Galenos Yayıncılık, 2010)Giant cell hepatitis associated with direct Coombs' test-positive hemolytic anemia is a rare condition of childhood and the pathogenesis remains unclear. An autoimmune activation and loss of self-tolerance in these patients ... -
Bacterial Infection Prevention After Hematopoietic Cell Transplantation
(Nature Publishing Group, 2009) -
Benefit Of High-Dose Methylprednisolone In Comparison With Conventional-Dose Prednisolone During Remission Induction Therapy In Childhood Acute Lymphoblastic Leukemia For Long-Term Follow-Up
(Nature Publishing Group, 2003)Eight-year event-free survival (EFS) was evaluated in 205 patients with acute lymphoblastic leukemia (ALL), to consider the efficacy of high-dose methylprednisolone (HDMP) given during remission induction chemotherapy ... -
Beta-Globin Haplotype And Xmni Polymorphism At Position G-Gamma-158 And Hbf Production In Fanconis Anemia
(Ferrata Storti Foundation, 1992)Background. Patients with aplastic anemia show to a variable degree an increase of the red blood cell volume and percentage of HbF. The extent of HbF reactivation in sickle cell anemia and thalassemia major is related to ... -
Can Restoring Incomplete Microcirculatory Reperfusion Improve Stroke Outcome After Thrombolysis?
(Sage Publications Inc, 2012)Substantial experimental data and recent clinical evidence suggesting that tissue reperfusion is a better predictor of outcome after thrombolysis than recanalization necessitate that patency of microcirculation after ... -
Cerebral Infarct Associated With Factor V Leiden Mutation In A Boy With Hemophilia A
(Wiley-Liss, 1997)An 11-year-old boy with mild hemophilia A was admitted to our hospital because of focal convulsions, Magnetic resonance imaging showed an old occipital infarct. Protein C, S, antithrombin ill, anticardiolipin antibodies ... -
Chronic Myeloid Leukemia Presenting With Visual And Auditory Impairment In An Adolescent: An Insight To Management Strategies
(Springer India, 2010)A 15-year-old girl presented with progressive deterioration in vision and hearing over 1 week. A huge spleen was palpated below the left costal margin laying down to inguinal region. Blood count showed hyperleukocytosis ... -
Clinical Investigation Of Oral Findings In Inherited Disorders Of Platelet Function
(Aves Yayincilik, 2011)Objective: Bleeding disorders are a very important health problem due to the associated high risk of hemorrhage during dental procedures. The present study aimed to investigate oral manifestations of inherited disorders ... -
Comparison Of Primary Human Cytotoxic T-Cell And Natural Killer Cell Responses Reveal Similar Molecular Requirements For Lytic Granule Exocytosis But Differences In Cytokine Production
(Amer Soc Hematology, 2013)Cytotoxic lymphocytes, encompassing cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, kill pathogen-infected, neoplastic, or certain hematopoietic cells through the release of perforin-containing lytic granules. ... -
Dysplastic Changes in Idiopathic Thrombocytopenic Purpura and The Effect of Corticosteroids to Increase Dysplasia and Cause Hyperdiploid Macropolycytes
(Wiley-Liss, 2000)This study evaluates the dysplastic hematological changes in nine patients with idiopathic thrombocytopenic purpura (ITP) in 11 attacks, before and after corticosteroid treatment. The pretreatment blood smears of patients ... -
Early Detection of Pulmonary Fungal Infection By Ct Scan in Pediatric All Patients Under Chemotherapy or In Post-Transplantation Period With Primary Complaint of Chest Pain
(Aves Yayincilik, 2010)We describe herein four children with acute lymphoblastic leukemia who were diagnosed as pulmonary fungal infection after presenting with chest pain. The plain radiologic evaluations failed to reveal any positive findings, ... -
Eculizumab Before and After Allogeneic Hematopoietic Stem Cell Transplantation in a Patient With Paroxysmal Nocturnal Hemoglobinuria
(Galenos Yayıncılık, 2011)Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by the triad of intravascular hemolysis, venous thrombosis, and cytopenia. Treatment of PNH is generally supportive. Bone marrow transplantation is the only curative ... -
Endothelial Nitric Oxide Synthase-Dependent Cerebral Blood Flow Augmentation By L-Arginine After Chronic Statin Treatment
(Sage Publications Inc, 2000)Nitric oxide, a product of nitric oxide synthase activity, relaxes vascular smooth muscle and elevates brain blood flow. We evaluated the importance of eNOS to cerebral blood flow augmentation after L-arginine infusion and ...