Başlık için Dahili Tıp Bilimleri Bölümü Makale Koleksiyonu listeleme
Toplam kayıt 2912, listelenen: 81-100
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A Multi-Institutional Analysis Of Sequential Versus ‘Sandwich’ Adjuvant Chemotherapy And Radiotherapy For Stage Iiic Endometrial Carcinoma
(2018)Objective To analyze the outcomes of sequential or sandwich chemotherapy (ChT) and radiotherapy (RT) in patients with node-positive endometrial cancer (EC). Methods Data from 4 centers were collected retrospectively for ... -
A Multidisciplinary Team Approach to the Management of Patients with Suspected or Diagnosed Invasive Fungal Disease
(Oxford Univ Press, 2013)Implementation of evidence-based guidelines for the treatment of invasive fungal disease (IFD) requires collaboration among numerous clinical and laboratory services, as partners in patient care. The multidisciplinary team ... -
A Multinational, Preregistered Cohort Study Of Beta-Lactam/Beta-Lactamase Inhibitor Combinations For Treatment Of Bloodstream Infections Due To Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae
(Amer Soc Microbiology, 2016)The spread of extended-spectrum-beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem consumption. Alternatives to carbapenems need to be investigated. We investigated whether ... -
A Nanomedicine Transports A Peptide Caspase-3 Inhibitor Across The Blood-Brain Barrier And Provides Neuroprotection
(Soc Neuroscience, 2009)Caspases play an important role as mediators of cell death in acute and chronic neurological disorders. Although peptide inhibitors of caspases provide neuroprotection, they have to be administered intracerebroventricularly ... -
A New Candidate As a Hemostatic Agent For Difficult Situations During Variceal Bleeding: Ankaferd Blood Stopper
(2011)Variceal bleeding is the most challenging emergent situation among the causes of upper gastrointestinal bleeding. Despite substantial improvement, a need remains for therapeutic armamentarium of such cases, which is easy, ... -
A New Potential Biomarker in Early Diagnosis of Firefighter Lung Function Impairment: Dynamic Thiol/Disulphide Homeostasis
(Natl Inst Public Health, 2018)Objectives: The aim of this study was to investigate the associations between urinary arsenic, oxidative stress, assessed by thiol/disulphide homeostasis, and lung diseases in firefighters. Methods: The study conducted ... -
A New Risk Scoring Model For Prediction of Poor Coronary Collateral Circulation in Acute Non-St-Elevation Myocardial Infarction
(Via Medica, 2016)Background: We aimed to investigate the clinical features associated with development of coronary collateral circulation (CCC) in patients with acute non-ST-elevation myocardial infarction (NSTEMI) and to develop a scoring ... -
A Novel Approach to Treatment in Childhood Acute Myeloblastic Leukemia and Myelodysplastic Syndrome with High-Dose Methylprednisolone As a Differentiation- and Apoptosis-Inducing Agent of Myeloid Leukemic Cells
(Galenos Yayıncılık, 2010)Differentiation-inducing therapy with all-trans retinoic acid significantly improved the outcome in children with acute promyelocytic leukemia (APL). Therefore, use of agents that induce differentiation of leukemic cells ... -
A Novel De Novo Mutation Involving the Mll2 Gene in a Kabuki Syndrome Patient Presenting with Seizures
(Turkish J Pediatrics, 2016)Kabuki syndrome is a rare multiple congenital anomaly disorder. Although mental retardation is one of the main features, various neurological symptoms such as hypotonia and seizures can occur. Here we report on a 18-year-old ... -
A Novel Immunosuppressive Agent, Sirolimus, in the Treatment of Kaposi'S Sarcoma in a Renal Transplant Recipient
(Taylor & Francis Inc, 2007)Renal transplant recipients are susceptible to Kaposi's sarcoma (KS) because of treatment with immunosuppressive drugs. Sirolimus, a new immunosuppressive agent, has been successfully used for immune-suppression in kidney ... -
A Novel Missense Mutation of the Grk1 Gene in Oguchi Disease
(2016)Oguchi disease is a rare form of congenital stationary night blindness with an autosomal recessive inheritance pattern. The presence of S-antigen (SAG) and G-protein-dependent receptor kinase 1 (GRK1) mutations were ... -
A Novel Mutation in the Complement Component 3 Gene in a Patient with Selective Iga Deficiency
(2013)Purpose Immunological and molecular evaluation of a patient presenting with recurrent infections caused by Streptococcus pneumoniae and low complement component 3 (C3) levels. Methods Immunological evaluation included ... -
A Novel Mutation in the Interleukin-1 Receptor Antagonist Associated with Intrauterine Disease Onset
(Academic Press Inc Elsevier Science, 2012)Deficiency of the IL-1 receptor antagonist (DIRA) is a recently described rare autoinflammatory disease, caused by loss of function mutations in IL1RN leading to the unopposed activation of the IL-1 pathway. We describe a ... -
A Novel Protein Tyrosine Phosphatase Gene is Mutated in Progressive Myoclonus Epilepsy of the Lafora Type (Epm2)
(Oxford Univ Press, 1999)Progressive myoclonus epilepsy of the Lafora type or Lafora disease (EPM2; McKusick no. 254780) is an autosomal recessive disorder characterized by epilepsy, myoclonus, progressive neurological deterioration and glycogen-like ... -
A Patient Heterozygous for R92Q Mutation with Periodic Fever and Aphthous Stomatitis, Pharyngitis, and Adenitis (Pfapa) Syndrome-Like Phenotype
(Turkish J Pediatrics, 2018)Tumor necrosis factor receptor associated periodic syndrome (TRAPS) is an autosomal dominant disease caused by mutations located on the type 1 tumor necrosis factor receptor (TNFRSF1A) gene. Here we present a 3-year-old ... -
A Patient-Derived and Patient-Reported Outcome Measure For Assessing Psoriatic Arthritis: Elaboration and Preliminary Validation of The Psoriatic Arthritis Impact of Disease (Psaid) Questionnaire, A 13-Country Eular Initiative
(BMJ, 2014)Introduction The objective was to develop a questionnaire that can be used to calculate a score reflecting the impact of psoriatic arthritis (PsA) from the patients' perspective: the PsA Impact of Disease (PsAID) questionnaire. ...