• Differential Roles Of Microglia And Monocytes In The Inflamed Central Nervous System 

      Yamasaki, Ryo; Lu, Haiyan; Butovsky, Oleg; Ohno, Nobuhiko; Rietsch, Anna M.; Cialic, Ron; Wu, Pauline M.; Doykan, Camille E.; Lin, Jessica; Cotleur, Anne C.; Kidd, Grahame; Zorlu, Musab M.; Sun, Nathan; Hu, Weiwei; Liu, LiPing; Lee, Jar-Chi; Taylor, Sarah E.; Uehlein, Lindsey; Dixon, Debra; Gu, Jinyu; Floruta, Crina M.; Zhu, Min; Charo, Israel F.; Weiner, Howard L.; Ransohoff, Richard M. (Rockefeller Univ Press, 2014)
      In the human disorder multiple sclerosis (MS) and in the model experimental autoimmune encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their numbers correlate to tissue damage. Macrophages may ...
    • Differentiating Reversible Cerebral Vasoconstriction Syndrome With Subarachnoid Hemorrhage From Other Causes Of Subarachnoid Hemorrhage 

      Muehlschlegel, Susanne; Kursun, Oğuzhan; Topçuoğlu, Mehmet A.; Fok, Joshua; Singhal, Aneesh B. (Amer Medical Assoc, 2013)
      IMPORTANCE Reversible cerebral vasoconstriction syndrome (RCVS) is a clinical-angiographic syndrome characterized by recurrent thunderclap headaches and reversible segmental multifocal cerebral artery narrowing. More than ...
    • Diffuse Large B Cell Lymphoma With Extensive Cutaneous Relapse 

      Malkan, Ümit Yavuz; Güneş, Gürsel; Yayar, Okan; Demiroğlu, Haluk (2015)
      Herein, we aimed to report a diffuse large B cell lymphoma (DLBCL) case that had extensive cutaneous relapse with no skin involvement previously. A 59-year-old man presented to hospital in April 2014 with fatigue, anorexia, ...
    • Diffusion Mr Imaging Features Of Skull Base Osteomyelitis Compared With Skull Base Malignancy 

      Özgen, B.; Oğuz, K. K.; Cila, A. (Amer Soc Neuroradiology, 2011)
      BACKGROUND AND PURPOSE: SBO is a life-threatening infection that may have radiologic features similar to those of the neoplastic processes. The purpose of this study was to evaluate the DWI findings in SBO to facilitate ...
    • Diffusion-Weighted Mri For Detecting And Monitoring Cancer: A Review Of Current Applications In Body Imaging 

      Türkbey, Barış; Aras, Ömer; Karabulut, Nevzat; Turgut, Ahmet Tuncay; Akpınar, Erhan; Alibek, Sedat; Pang, Yuxi; Erturk, Sukru Mehmet; El Khouli, Riham H.; Bluemke, David A.; Choyke, Peter L. (Aves, 2012)
      Diffusion-weighted magnetic resonance imaging (MRI), Which involves the acquisition of a magnetic resonance signal related to the Brownian motion of water protons in tissue, has become a useful technique for assessing ...
    • Direct And Indirect Costs Associated With Ankylosing Spondylitis And Related Disease Activity Scores In Turkey 

      Akkoç, Nurullah; Direskeneli, Haner; Erdem, Hakan; Gül, Ahmet; Kabasakal, Yasemin; Kiraz, Sedat; Balkan Tezer, Dilara; Hacıbedel, Başak; Hamuryudan, Vedat (2015)
      This study assessed quality of life, direct and indirect healthcare costs related to ankylosing spondylitis (AS). This study included 650 prevalent AS patients visiting seven centers at tertiary healthcare institutions in ...
    • Discontinuation Of Imatinib Mesylate Could Improve Renal Impairment In Chronic Myeloid Leukemia 

      Malkan, Umit Y.; Haznedaroglu, Ibrahim C. (2019)
      We aim to report a CML case that had fluid retention and serum creatinine increase under long-term imatinib mesylate (IM) treatment. A 68-year-old woman was diagnosed with chronic myeloid leukemia, and IM was started in ...
    • Disease Activity In Paediatric Vasculitis: Development Of A Generic Assessment Tool - Pvas 

      Dolezalova, P; Brogan, PA; Özen, S; Benseler, S; Anton, J; Brunner, J; Cabral, DA; Cimaz, R; O´Neil, KM; Wallace, C; Wilkinson, N; Luqmani, R (2011)
    • Disease Course And Treatment Responses In Children With Relapsingmyelin Oligodendrocyte Glycoprotein Antibody-Associated Disease 

      Hacohen, Yael; YiWong, Yu; Lechner, Christian; Jurynczyk, Maciej; Wright, Sukhvir; Konuskan, Bahadir; Kalser, Judith; Poulat, Anne Lise; Maurey, Helene; Ganelin-Cohen, Esther; Wassmer, Evangeline; Hemingway, Chery; Forsyth, Rob; Hennes, Eva Maria; Leite, Isabel; Ciccarelli, Olga; Anlar, Banu; Hintzen, Rogier; Marignier, Romain; Palace, Jacqueline; Baumann, Matthias; Rostasy, Kevin; Neuteboom, Rinze; Deiva, Kumaran; Lim, Ming (Amer Medical Assoc, 2018)
      IMPORTANCE Myelin oligodendrocyte glycoprotein antibodies (MOG-Abs) are consistently identified in a range of demyelinating disorders in adults and children. Current therapeutic strategies are largely center specific, and ...
    • Disease Of The Sultans: Metabolic Syndrome In Ottoman Dynasty 

      Dağdelen, Selçuk; Erbas, Tomris (Aves Yayincilik, 2010)
      Metabolic syndrome is generally considered as a complication of modernity. Here we searched for the presence of metabolic syndrome components among the Ottoman emperors who lived between 1258 and 1926. Collections of ...
    • Disfaji ile gelen vitamin B12 eksikliği: Bir vaka takdimi 

      Usta, Yusuf; Çetinkaya, Ahmet; Aydemir, Yusuf; Kuskonmaz, Baris; Gürakan, Figen; Cetin, Mualla (2007)
    • Disparities In Treatment Rates Of Paediatric End-Stage Renal Disease Across Europe: Insights From The Espn/Era-Edta Registry 

      Chesnaye, Nicholas C.; Schaefer, Franz; Groothoff, Jaap W.; Caskey, Fergus J.; Heaf, James G.; Kushnirenko, Stella; Lewis, Malcolm; Mauel, Reiner; Maurer, Elisabeth; Merenmies, Jussi; Shtiza, Diamant; Topaloglu, Rezan; Zaicova, Natalia; Zampetoglou, Argyroula; Jager, Kitty J.; van Stralen, Karlijn J. (Oxford Univ Press, 2015)
      Background. Considerable disparities exist in the provision of paediatric renal replacement therapy (RRT) across Europe. This study aims to determine whether these disparities arise from geographical differences in the ...
    • Disruption Of A Long-Range Cis-Acting Regulator For Shh Causes Preaxial Polydactyly 

      Lettice, LA; Horikoshi, T; Heaney, SJH; van Baren, MJ; van der Linde, HC; Breedveld, GJ; Joosse, M; Akarsu, N; Oostra, BA; Endo, N; Shibata, M; Suzuki, M; Takahashi, E; Shinka, T; Nakahori, Y; Ayusawa, D; Nakabayashi, K; Scherer, SW; Heutink, P; Hill, RE; Noji, S (Natl Acad Sciences, 2002)
      Preaxial polydactyly (PPD) is a common limb malformation in human. A number of polydactylous mouse mutants indicate that misexpression of Shh is a common requirement for generating extra digits. Here we identify a translocation ...
    • Disruption of Alx1 Causes Extreme Microphthalmia and Severe Facial Clefting: Expanding The Spectrum of Autosomal-Recessive Alx-Related Frontonasal Dysplasia 

      Uz, Elif; Alanay, Yasemin; Aktas, Dilek; Vargel, Ibrahim; Gucer, Safak; Tuncbilek, Gokhan; von Eggeling, Ferdinand; Yilmaz, Engin; Deren, Ozgur; Posorski, Nicole; Ozdag, Hilal; Liehr, Thomas; Balci, Sevim; Alikasifoglu, Mehmet; Wollnik, Bernd; Akarsu, Nurten A. (Cell Press, 2010)
      We present an autosomal-recessive frontonasal dysplasia (FND) characterized by bilateral extreme microphthalmia, bilateral oblique facial cleft, complete cleft palate, hypertelorism, wide nasal bridge with hypoplasia of ...
    • Disruption of Ptpro Causes Childhood-Onset Nephrotic Syndrome 

      Ozaltin, Fatih; Ibsirlioglu, Tulin; Taskiran, Ekim Z.; Baydar, Dilek Ertoy; Kaymaz, Figen; Buyukcelik, Mithat; Kilic, Beltinge Demircioglu; Balat, Ayse; Iatropoulos, Paraskevas; Asan, Esin; Akarsu, Nurten A.; Schaefer, Franz; Yilmaz, Engin; Bakkaloglu, Aysin (Cell Press, 2011)
      Idiopathic nephrotic syndrome (INS) is a genetically heterogeneous group of disorders characterized by proteinuria, hypoalbuminemia, and edema. Because it typically results in end-stage kidney disease, the steroid-resistant ...
    • Disruption of the Podosome Adaptor Protein Tks4 (Sh3Pxd2B) Causes The Skeletal Dysplasia, Eye, and Cardiac Abnormalities of Frank-Ter Haar Syndrome 

      Iqbal, Zafar; Cejudo-Martin, Pilar; de Brouwer, Arjan; van der Zwaag, Bert; Ruiz-Lozano, Pilar; Scimia, M. Cecilia; Lindsey, James D.; Weinreb, Robert; Albrecht, Beate; Megarbane, Andre; Alanay, Yasemin; Ben-Neriah, Ziva; Amenduni, Mariangela; Artuso, Rosangela; Veltman, Joris A.; van Beusekom, Ellen; Oudakker, Astrid; Millan, Jose Luis; Hennekam, Raoul; Hamel, Ben; Courtneidge, Sara A.; van Bokhoven, Hans (Cell Press, 2010)
      Frank-Ter Haar syndrome (FTHS), also known as Ter Haar syndrome, is an autosomal-recessive disorder characterized by skeletal, cardiovascular, and eye abnormalities, such as increased intraocular pressure, prominent eyes, ...
    • Distal Middle Cerebral Artery Aneurysms - Endovascular Treatment Results With Literature Review 

      Baltacıoğlu, F; Cekirge, S; Saatçi, I; Özturk, H; Arat, A; Pamir, N; Ozgen, T (Edizioni Centauro, 2002)
      Intracranial aneurysms of the distal intracranial arteries are uncommon lesions which are difficult to treat with surgical techniques. Distal middle cerebral artery (MCA) aneurysms constitute approximately 5% of all MCA ...
    • Distribution of Ret Mutations And Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma In Turkey 

      Aydoğan, Berna İmge; Yüksel, Bağdagül; Tuna, Mazhar Müslüm; Navdar Başaran, Mehtap; Akkurt Kocaeli, Ayşen; Ertörer, Melek Eda; Aydın, Kadriye; Güldiken, Sibel; Şimşek, Yasin; Cihan Karaca, Züleyha; Yılmaz, Merve; Aktürk, Müjde; Anaforoğlu, İnan; Kebapçı, Nur; Duran, Cevdet; Taşlıpınar, Abdullah; Kulaksızoğlu, Mustafa; Gürsoy, Alptekin; Dağdelen, Selçuk; Erdoğan, Murat Faik (2016)
      Objective: This retrospective multicenter study, centrally conducted and supported by the Society of Endocrinology and Metabolism of Turkey, aimed to evaluate the impact of free RET proto-oncogene testing in medullary ...
    • Distribution Of Streptococcus Pneumoniae Serotypes That Cause Parapneumonic Empyema In Turkey 

      Ceyhan, Mehmet; Özsurekci, Yasemin; Gürler, Nezahat; Özkan, Şengül; Şensoy, Gulnar; Belet, Nursen; Hacimustafaoglu, Mustafa; Celebi, Solmaz; Keser, Melike; Dinleyici, Ener Cagri; Alhan, Emre; Baki, Ali; Oner, Ahmet Faik; Uzun, Hakan; Kurugol, Zafer; Aycan, Ahmet Emre; Gurbuz, Venhar; Oncel, Eda Karadag; Celik, Melda; Parlakay, Aslinur Ozkaya (Amer Soc Microbiology, 2013)
      Streptococcus pneumoniae is the most common etiological cause of complicated pneumonia, including empyema. In this study, we investigated the serotypes of S. pneumoniae that cause empyema in children. One hundred fifty-six ...