• Invasive Pneumococcal Disease: From a Tertiary Care Hospital in the Post-Vaccine Era 

      Basaranoglu, Sevgen Tanir; Oncel, Eda Karadag; Aykac, Kubra; Ozsurekci, Yasemin; Cengiz, Ali Bulent; Kara, Ates; Ceyhan, Mehmet (Taylor & Francis Inc, 2017)
      A breakthrough infection occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in Turkey are previously described. A breakthrough infection is defined as IPD in a child who had received 1 PCV-7 or PCV-13 and for ...
    • Invasive Pneumococcal Infection Due to Serotype 15A after the Pneumococcal Conjugate Vaccine Implementation in Turkey 

      Buyukcam, Ayse; Guducuoglu, Huseyin; Karaman, Kamuran; Gurbuz, Venhar; Aliyev, Emil; Kara, Ates; Ceyhan, Mehmet (Taylor & Francis Inc, 2017)
      Invasive pneumococcal infections among children are a serious public health problem in many countries, including Turkey. Pneumococcal conjugate vaccine has been included in Turkey's National Immunization Programme since ...
    • Life-Threatening Neurological Complications after Bone Marrow Transplantation in Children 

      Uckan, D; Cetin, M; Yigitkanli, I; Tezcan, I; Tuncer, M; Karasimav, D; Oguz, KK; Topcu, M (Nature Publishing Group, 2005)
      Neurological complications may occur in BMT recipients (11-59%), frequently contributing to morbidity or mortality. They are the main causes of death in 10-15%. Life-threatening neurological complications were seen in 11 ...
    • Macvia-Aria Sentinel Network for Allergic Rhinitis (Mask-Rhinitis): The New Generation Guideline Implementation 

      Bousquet, J.; Schunemann, H. J.; Fonseca, J.; Samolinski, B.; Bachert, C.; Canonica, G. W.; Casale, T.; Cruz, A. A.; Demoly, P.; Hellings, P.; Valiulis, A.; Wickman, M.; Zuberbier, T.; Bosnic-Anticevitch, S.; Bedbrook, A.; Bergmann, K. C.; Caimmi, D.; Dahl, R.; Fokkens, W. J.; Grisle, I.; Lodrup Carlsen, K.; Mullol, J.; Muraro, A.; Palkonen, S.; Papadopoulos, N.; Passalacqua, G.; Ryan, D.; Valovirta, E.; Yorgancioglu, A.; Aberer, W.; Agache, I.; Adachi, M.; Akdis, C. A.; Akdis, M.; Annesi-Maesano, I.; Ansotegui, I. J.; Anto, J. M.; Arnavielhe, S.; Arshad, H.; Baiardini, I.; Baigenzhin, A. K.; Barbara, C.; Bateman, E. D.; Beghe, B.; Bel, E. H.; Ben Kheder, A.; Bennoor, K. S.; Benson, M.; Bewick, M.; Bieber, T.; Bindslev-Jensen, C.; Bjermer, L.; Blain, H.; Boner, A. L.; Boulet, L. P.; Bonini, M.; Bonini, S.; Bosse, I.; Bourret, R.; Bousquet, P. J.; Braido, F.; Briggs, A. H.; Brightling, C. E.; Brozek, J.; Buhl, R.; Burney, P. G.; Bush, A.; Caballero-Fonseca, F.; Calderon, M. A.; Camargos, P. A. M.; Camuzat, T.; Carlsen, K. H.; Carr, W.; Sarabia, A. M. Cepeda; Chavannes, N. H.; Chatzi, L.; Chen, Y. Z.; Chiron, R.; Chkhartishvili, E.; Chuchalin, A. G.; Ciprandi, G.; Cirule, I.; Correia de Sousa, J.; Cox, L.; Crooks, G.; Costa, D. J.; Custovic, A.; Dahlen, S. E.; Darsow, U.; De Carlo, G.; De Blay, F.; Dedeu, T.; Deleanu, D.; Denburg, J. A.; Devillier, P.; Didier, A.; Dinh-Xuan, A. T.; Dokic, D.; Douagui, H.; Dray, G.; Dubakiene, R.; Durham, S. R.; Dykewicz, M. S.; El-Gamal, Y.; Emuzyte, R.; Wagner, A. Fink; Fletcher, M.; Fiocchi, A.; Forastiere, F.; Gamkrelidze, A.; Gemicioglu, B.; Gereda, J. E.; Gonzalez Diaz, S.; Gotua, M.; Grouse, L.; Guzman, M. A.; Haahtela, T.; Hellquist-Dahl, B.; Heinrich, J.; Horak, F.; Hourihane, J. O. B.; Howarth, P.; Humbert, M.; Hyland, M. E.; Ivancevich, J. C.; Jares, E. J.; Johnston, S. L.; Joos, G.; Jonquet, O.; Jung, K. S.; Just, J.; Kaidashev, I.; Kalayci, O.; Kalyoncu, A. F.; Keil, T.; Keith, P. K.; Khaltaev, N.; Klimek, L.; N'Goran, B. Koffi; Kolek, V.; Koppelman, G. H.; Kowalski, M. L.; Kull, I.; Kuna, P.; Kvedariene, V.; Lambrecht, B.; Lau, S.; Larenas-Linnemann, D.; Laune, D.; Le, L. T. T.; Lieberman, P.; Lipworth, B.; Li, J.; Louis, R.; Magard, Y.; Magnan, A.; Mahboub, B.; Majer, I.; Makela, M. J.; Manning, P.; De Manuel Keenoy, E.; Marshall, G. D.; Masjedi, M. R.; Maurer, M.; Mavale-Manuel, S.; Melen, E.; Melo-Gomes, E.; Meltzer, E. O.; Merk, H.; Miculinic, N.; Mihaltan, F.; Milenkovic, B.; Mohammad, Y.; Molimard, M.; Momas, I.; Montilla-Santana, A.; Morais-Almeida, M.; Moesges, R.; Namazova-Baranova, L.; Naclerio, R.; Neou, A.; Neffen, H.; Nekam, K.; Niggemann, B.; Nyembue, T. D.; O'Hehir, R. E.; Ohta, K.; Okamoto, Y.; Okubo, K.; Ouedraogo, S.; Paggiaro, P.; Pali-Schoell, I.; Palmer, S.; Panzner, P.; Papi, A.; Park, H. S.; Pavord, I.; Pawankar, R.; Pfaar, O.; Picard, R.; Pigearias, B.; Pin, I.; Plavec, D.; Pohl, W.; Popov, T. A.; Portejoie, F.; Postma, D.; Potter, P.; Price, D.; Rabe, K. F.; Raciborski, F.; Pontal, F. Radier; Repka-Ramirez, S.; Robalo-Cordeiro, C.; Rolland, C.; Rosado-Pinto, J.; Reitamo, S.; Rodenas, F.; Roman Rodriguez, M.; Romano, A.; Rosario, N.; Rosenwasser, L.; Rottem, M.; Sanchez-Borges, M.; Scadding, G. K.; Serrano, E.; Schmid-Grendelmeier, P.; Sheikh, A.; Simons, F. E. R.; Sisul, J. C.; Skrindo, I.; Smit, H. A.; Sole, D.; Sooronbaev, T.; Spranger, O.; Stelmach, R.; Strandberg, T.; Sunyer, J.; Thijs, C.; Todo-Bom, A.; Triggiani, M.; Valenta, R.; Valero, A. L.; van Hage, M.; Vandenplas, O.; Vezzani, G.; Vichyanond, P.; Viegi, G.; Wagenmann, M.; Walker, S.; Wang, D. Y.; Wahn, U.; Williams, D. M.; Wright, J.; Yawn, B. P.; Yiallouros, P. K.; Yusuf, O. M.; Zar, H. J.; Zernotti, M. E.; Zhang, L.; Zhong, N.; Zidarn, M.; Mercier, J. (Wiley, 2015)
      Several unmet needs have been identified in allergic rhinitis: identification of the time of onset of the pollen season, optimal control of rhinitis and comorbidities, patient stratification, multidisciplinary team for ...
    • Management of Hypersensitivity Reactions to Proton Pump Inhibitors: A Retrospective Experience 

      Ozdemir, Secil Kepil; Erkekol, Ferda Oner; Unal, Derya; Buyukozturk, Suna; Gelincik, Asli; Dursun, Adile Berna; Karakaya, Gul; Bavbek, Sevim (Karger, 2016)
      Background: We previously reported perfect specificity and low sensitivity of skin tests in proton pump inhibitor (PPI)-induced immediate hypersensitivity reactions in a prospective multicenter study. Here, in a retrospective ...
    • Meningitis Caused By Neisseria Meningitidis, Hemophilus Influenzae Type B And Streptococcus Pneumoniae During 2005-2012 In Turkey A Multicenter Prospective Surveillance Study 

      Ceyhan, Mehmet; Gurler, Nezahat; Ozsurekci, Yasemin; Keser, Melike; Aycan, Ahmet Emre; Gurbuz, Venhar; Salman, Nuran; Camcioglu, Yildiz; Dinleyici, Ener Cagri; Ozkan, Sengul; Sensoy, Gulnar; Belet, Nursen; Alhan, Emre; Hacimustafaoglu, Mustafa; Celebi, Solmaz; Uzun, Hakan; Oner, Ahmet Faik; Kurugol, Zafer; Tas, Mehmet Ali; Aygun, Denizmen; Oncel, Eda Karadag; Celik, Melda; Yasa, Olcay; Akin, Fatih; Coskun, Yavuz (Taylor & Francis Inc, 2014)
      Successful vaccination policies for protection from bacterial meningitis are dependent on determination of the etiology of bacterial meningitis. Cerebrospinal fluid (CSF) samples were obtained prospectively from children ...
    • Missed Opportunities For Hepatitis B Vaccination Among Diabetic Patients 

      Ozisik, Lale; Tanriover, Mine Durusu; Basaran, Nursel Calik; Oz, S. Gul; Unal, Serhat (Taylor & Francis Inc, 2015)
      Many infectious diseases in adults can be prevented by a life-long vaccination strategy'. Hepatitis B disease burden was shown to be higher in diabetic patients. American Advisory Committee on Immunization Practices ...
    • Mutations In Stat3 And Diagnostic Guidelines For Hyper-Ige Syndrome 

      Woellner, Cristina; Gertz, E. Michael; Schaeffer, Alejandro A.; Lagos, Macarena; Perro, Mario; Glocker, Erik-Oliver; Pietrogrande, Maria C.; Cossu, Fausto; Franco, Josee L.; Matamoros, Nuria; Pietrucha, Barbara; Heropolitanska-Pliszka, Edyta; Yeganeh, Mehdi; Moin, Mostafa; Espanol, Teresa; Ehl, Stephan; Gennery, Andrew R.; Abinun, Mario; Breborowicz, Anna; Niehues, Tim; Kilic, Sara Sebnem; Junker, Anne; Turvey, Stuart E.; Plebani, Alessandro; Sanchez, Berta; Garty, Ben-Zion; Pignata, Claudio; Cancrini, Caterina; Litzman, Jiri; Sanal, Oezden; Baumann, Ulrich; Bacchetta, Rosa; Hsu, Amy P.; Davis, Joie N.; Hammarstroem, Lennart; Davies, E. Graham; Eren, Efrem; Arkwright, Peter D.; Moilanen, Jukka S.; Viemann, Dorothee; Khan, Sujoy; Laszlo Marodi; Cant, Andrew J.; Freeman, Alexandra F.; Puck, Jennifer M.; Holland, Steven M.; Grimbacher, Bodo (Mosby-Elsevier, 2010)
      Background: The hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by infections of the lung and skin, elevated serum IgE, and involvement of the soft and bony tissues. Recently, HIES has been associated ...
    • Neisseria Meningitidis Serogroup X St-5799 (St-22 Complex) In Turkey: A Unique Pediatric Case 

      Tanir, Gonul; Ozsurekci, Yasemin; Lucidarme, Jay; Durmus, Sevgi Yasar; Lekshmi, Aiswarya; Akisoglu, Ozlem; Aycan, Ahmet Emre; Borrow, Ray; Ceyhan, Mehmet (Taylor & Francis Inc, 2018)
      Although outbreaks of Neisseria meningitidis serogroup X occured in a couple of African countries, a limited number of serogroup X meningococcal cases were reported in America and Europe as well as Turkey. Additionally, ...
    • Parasitic Infections in Children With Chronic Spontaneous Urticaria 

      Yilmaz, Ebru Arik; Karaatmaca, Betul; Sackesen, Cansin; Sahiner, Umit Murat; Cavkaytar, Ozlem; Sekerel, Bulent E.; Soyer, Ozge (Karger, 2016)
      Background: Parasites have been proposed to be an underlying cause of chronic spontaneous urticaria (CSU) in childhood, but a clear causal relationship between them has not been established. This study aimed to investigate ...
    • Pharmacokinetics of Colchicine in Pediatric and Adult Patients with Familial Mediterranean Fever 

      Berkun, Y.; Wason, S.; Brik, R.; Butbul, Y.; Ben-Chetrit, E.; Hashkes, P. J.; Livneh, A.; Ozen, Seza; Ozdogan, H.; Faulkner, R.; Davis, M. W. (Biolife Sas, 2012)
      This study sought to determine the appropriate starting dose of colchicine in children aged 2 to 4 years with familial Mediterranean fever (FMF) based on steady-state pharmacokinetics in pediatric patients with FMF >= 2 ...
    • Primary Cutaneous Aspergillosis in Human Immunodeficiency Virus-Infected Patients: Two Cases and Review 

      Arikan, S; Uzun, O; Cetinkaya, Y; Kocagoz, S; Akova, M; Unal, S (Univ Chicago Press, 1998)
    • Rasgrp1 Deficiency Causes Immunodeficiency With Impaired Cytoskeletal Dynamics 

      Salzer, Elisabeth; Cagdas, Deniz; Hons, Miroslav; Mace, Emily M.; Garncarz, Wojciech; Petronczki, Ozlem Yuce; Platzer, Rene; Pfajfer, Laurene; Bilic, Ivan; Ban, Sol A.; Willmann, Katharina L.; Mukherjee, Malini; Supper, Verena; Hsu, Hsiang Ting; Banerjee, Pinaki P.; Sinha, Papiya; McClanahan, Fabienne; Zlabinger, Gerhard J.; Pick, Winfried F.; Gribben, John G.; Stockinger, Hannes; Bennett, Keiryn L.; Huppa, Johannes B.; Dupre, Loic; Sanal, Ozden; Jager, Ulrich; Sixt, Michael; Tezcan, Ilhan; Orange, Jordan S.; Boztug, Kaan (Nature Publishing Group, 2016)
      RASGRP1 is an important guanine nucleotide exchange factor and activator of the RAS-MAPK pathway following T cell antigen receptor (TCR) signaling. The consequences of RASGRP1 mutations in humans are unknown. In a patient ...
    • Recurrent Viral Infections Associated with a Homozygous Coro1A Mutation That Disrupts Oligomerization and Cytoskeletal Association 

      Yee, Christina S.; Massaad, Michel J.; Bainter, Wayne; Ohsumi, Toshiro K.; Foeger, Niko; Chan, Andrew C.; Akarsu, Nurten A.; Aytekin, Caner; Ayvaz, Deniz Cagdas; Tezcan, Ilhan; Sanal, Ozden; Geha, Raif S.; Chou, Janet (Mosby-Elsevier, 2016)
      Background: Coronin-1A (CORO1A) is a regulator of actin dynamics important for T-cell homeostasis. CORO1A deficiency causes T-B+ natural killer-positive severe combined immunodeficiency or T-cell lymphopenia with severe ...
    • Regulatory T Cells And Immune Regulation Of Allergic Diseases: Roles Of Il-10 And Tgf-Beta 

      Palomares, O.; Martin-Fontecha, M.; Lauener, R.; Traidl-Hoffmann, C.; Cavkaytar, O.; Akdis, M.; Akdis, C. A. (Nature Publishing Group, 2014)
      The prevalence of allergic diseases has significantly increased in industrialized countries. Allergen-specific immunotherapy (AIT) remains as the only curative treatment. The knowledge about the mechanisms underlying healthy ...
    • Right Middle Lobe Atelectasis In Children With Asthma And Prognostic Factors 

      Soyer, Özge; Özen, Cınar; Cavkaytar, Özlem; Senyucel, Cagrı; Dallar, Yıldız (Japanese Society Allergology, 2016)
      Background: Although right middle lobe (RML)-atelectasis of the lungs is a common complication of asthma, the relevant data is limited. The aim of this study is to define the characteristics of RML atelectasis in asthma ...
    • Risk Factors and Predictors of Outcome in Patients with Cancer and Breakthrough Candidemia 

      Uzun, O; Ascioglu, S; Anaissie, EJ; Rex, JH (Univ Chicago Press, 2001)
      Hematogenous candidiasis adds substantially to the morbidity and mortality rates of patients with cancer. Little is known about the risk factors and outcome in patients with breakthrough (BT) candidemia while on systemic ...
    • Serotype Distribution of Streptococcus Pneumoniae in Children with Invasive Diseases in Turkey: 2008-2014 

      Ceyhan, Mehmet; Özsürekci, Yasemin; Gürler, Nezahat; Öksüz, Lutfiye; Aydemir, Sohret; Özkan, Sengül; Yüksekkaya, Serife; Emiroglu, Melike Keser; Gültekin, Meral; Yaman, Akgün; Kiremitci, Abdurrahman; Yanik, Keramettin; Karlı, Arzu; Özcinar, Hatice; Aydın, Faruk; Bayramoğlu, Gülcin; Zer, Yasemin; Gülay, Zeynep; Gayyurhan, Efgan Doğan; Gül, Mustafa; Özakin, Cüneyt; Güdücuoğlu, Hüseyin; Percin, Duygu; Akpolat, Nezahat; Öztürk, Candan; Camcıoglu, Yıldız; Öncel, Eda Karadağ; Celik, Melda; Sanal, Laser; Uslu, Hakan (Taylor & Francis Inc, 2016)
      Successful vaccination policies for protection from invasive pneumococcal diseases (IPD) dependent on determination of the exact serotype distribution in each country. We aimed to identify serotypes of pneumococcal strains ...
    • Serotypes of Streptococcus Pneumoniae Isolates from Children with Invasive Pneumococcal Disease in Turkey: Baseline Evaluation of the Introduction of the Pneumococcal Conjugate Vaccine Nationwide 

      Ceyhan, Mehmet; Gurler, Nezahat; Yaman, Akgun; Ozturk, Candan; Oksuz, Lutfiye; Ozkan, Sengul; Keser, Melike; Salman, Nuran; Alhan, Emre; Esel, Duygu; Gultekin, Meral; Camcioglu, Yildiz; Gul, Mustafa; Sorguc, Yelda; Aydemir, Sohret; Gunaydin, Murat; Yakupogullari, Yusuf; Kizirgil, Ahmet (Amer Soc Microbiology, 2011)
      Before use of the pneumococcal conjugate vaccine PCV7 became widespread in Turkey, 202 invasive pneumococcus isolates were analyzed. The most common serotypes were 19F and 6B. In children <= 2 years of age, the potential ...
    • Serum Toll-Like Receptor-2, Toll-Like Receptor-4 Levels In Patients With Hbeag-Negative Chronic Viral Hepatitis B 

      Akbal, Erdem; Kocak, Erdem; Koklu, Seyfettin; Ergul, Bilal; Akyurek, Omer; Yilmaz, Fatma Meric (Mary Ann Liebert, Inc, 2017)
      Toll-like receptors (TLRs) may play an important role in hepatitis-B pathogenesis. However, serum TLR-2 and TLR-4 levels and their association with serum liver enzymes, hepatitis B virus (HBV) DNA, quantitative HBsAg levels, ...