Dil "en" Dahili Tıp Bilimleri Bölümü Makale Koleksiyonu için listeleme
Toplam kayıt 1961, listelenen: 41-60
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A Large Turkish Kindred With Syndactyly Type-II (Synpolydactyly) .2. Homozygous Phenotype
(British Med Journal Publ Group, 1995)Syndactyly type II (synpolydactyly (SPD)) is an autosomal dominant condition with typical abnormalities of the distal parts of both upper and lower limbs. We report here a previously undescribed phenotypic feature of people ... -
A Model of Complaint Based for Overcrowding Emergency Department: Five-Level Hacettepe Emergency Triage System
(Turkish Assoc Trauma Emergency Surgery, 2013)BACKGROUND To compare ESI Five-Level Triage System with 5-Level Hacettepe Emergency Triage System (HETS), which was developed for Overcrowded EDs in our country. METHODS Over a period of six days, patients were assessed ... -
A Molecular and Clinical Study of Larsen Syndrome Caused by Mutations in FLNB
(BMJ, 2007)Background: Larsen syndrome is an autosomal dominant osteochondrodysplasia characterised by large-joint dislocations and craniofacial anomalies. Recently, Larsen syndrome was shown to be caused by missense mutations or ... -
A Monogenic Disease with a Variety of Phenotypes: Deficiency of Adenosine Deaminase 2
(J Rheumatol Publ Co, 2019-05-01)Objective: Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disorder associated with ADA2 mutations. We aimed to investigate the characteristics and ADA2 enzyme activities of patients ... -
A Multi-Center Study On The Efficacy Of Eltrombopag In Management Of Refractory Chronic Immune Thrombocytopenia: A Real-Life Experience
(2019)Objective: The aim of the present study was to evaluate the efficacy and safety of eltrombopag, an oral thrombopoietin receptor agonist, in patients with chronic immune thrombocytopenia (ITP). Materials and Methods: A total ... -
A Multi-Institutional Analysis Of Sequential Versus `Sandwich' Adjuvant Chemotherapy And Radiotherapy For Stage Iiic Endometrial Carcinoma
(2019)Objective: To analyze the outcomes of sequential or sandwich chemotherapy (ChT) and radiotherapy (RT) in patients with node-positive endometrial cancer (EC). Methods: Data from 4 centers were collected retrospectively for ... -
A Multidisciplinary Team Approach to the Management of Patients with Suspected or Diagnosed Invasive Fungal Disease
(Oxford Univ Press, 2013)Implementation of evidence-based guidelines for the treatment of invasive fungal disease (IFD) requires collaboration among numerous clinical and laboratory services, as partners in patient care. The multidisciplinary team ... -
A Multinational, Preregistered Cohort Study Of Beta-Lactam/Beta-Lactamase Inhibitor Combinations For Treatment Of Bloodstream Infections Due To Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae
(Amer Soc Microbiology, 2016)The spread of extended-spectrum-beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) is leading to increased carbapenem consumption. Alternatives to carbapenems need to be investigated. We investigated whether ... -
A Nanomedicine Transports A Peptide Caspase-3 Inhibitor Across The Blood-Brain Barrier And Provides Neuroprotection
(Soc Neuroscience, 2009)Caspases play an important role as mediators of cell death in acute and chronic neurological disorders. Although peptide inhibitors of caspases provide neuroprotection, they have to be administered intracerebroventricularly ... -
A New Potential Biomarker in Early Diagnosis of Firefighter Lung Function Impairment: Dynamic Thiol/Disulphide Homeostasis
(Natl Inst Public Health, 2018)Objectives: The aim of this study was to investigate the associations between urinary arsenic, oxidative stress, assessed by thiol/disulphide homeostasis, and lung diseases in firefighters. Methods: The study conducted ... -
A New Risk Scoring Model For Prediction of Poor Coronary Collateral Circulation in Acute Non-St-Elevation Myocardial Infarction
(Via Medica, 2016)Background: We aimed to investigate the clinical features associated with development of coronary collateral circulation (CCC) in patients with acute non-ST-elevation myocardial infarction (NSTEMI) and to develop a scoring ... -
A Novel Approach to Treatment in Childhood Acute Myeloblastic Leukemia and Myelodysplastic Syndrome with High-Dose Methylprednisolone As a Differentiation- and Apoptosis-Inducing Agent of Myeloid Leukemic Cells
(Galenos Yayıncılık, 2010)Differentiation-inducing therapy with all-trans retinoic acid significantly improved the outcome in children with acute promyelocytic leukemia (APL). Therefore, use of agents that induce differentiation of leukemic cells ... -
A Novel De Novo Mutation Involving the Mll2 Gene in a Kabuki Syndrome Patient Presenting with Seizures
(Turkish J Pediatrics, 2016)Kabuki syndrome is a rare multiple congenital anomaly disorder. Although mental retardation is one of the main features, various neurological symptoms such as hypotonia and seizures can occur. Here we report on a 18-year-old ... -
A Novel Immunosuppressive Agent, Sirolimus, in the Treatment of Kaposi'S Sarcoma in a Renal Transplant Recipient
(Taylor & Francis Inc, 2007)Renal transplant recipients are susceptible to Kaposi's sarcoma (KS) because of treatment with immunosuppressive drugs. Sirolimus, a new immunosuppressive agent, has been successfully used for immune-suppression in kidney ... -
A Novel Mutation in the Interleukin-1 Receptor Antagonist Associated with Intrauterine Disease Onset
(Academic Press Inc Elsevier Science, 2012)Deficiency of the IL-1 receptor antagonist (DIRA) is a recently described rare autoinflammatory disease, caused by loss of function mutations in IL1RN leading to the unopposed activation of the IL-1 pathway. We describe a ... -
A Novel Protein Tyrosine Phosphatase Gene is Mutated in Progressive Myoclonus Epilepsy of the Lafora Type (Epm2)
(Oxford Univ Press, 1999)Progressive myoclonus epilepsy of the Lafora type or Lafora disease (EPM2; McKusick no. 254780) is an autosomal recessive disorder characterized by epilepsy, myoclonus, progressive neurological deterioration and glycogen-like ...