• Mitoxantrone-Melphalan Conditioning Regimen For Autologous Stem Cell Transplantation In Relapsed/Refractory Lymphoma 

      OKAY, Müfide; BÜYÜKAŞIK, Yahya; DEMİROĞLU, Haluk; MALKAN, Ümit Yavuz; ÇİFTÇİLER, Rafiye; ALADAĞ, Elifcan; AKSU, Salih; HAZNEDAROĞLU, İbrahim Celalettin; SAYINALP, Nilgün; ÖZCEBE, Osman İlhami; GÖKER, Hakan (2019)
      Background/aim High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) has become the standard approach for patients with relapsed/refractory Hodgkin’s lymphoma (HL) or non-Hodgkin’s lymphoma (NHL). ...
    • Moderation Analysis Exploring Associations Between Age And Mucocutaneous Activity in Behçet's Syndrome: A Multicenter Study From Turkey 

      Mumcu, Gonca; Yay, Meral; Karaçaylı, Ümit; Karadağ, Ömer; Armağan, B.; Ergun, T.; İnanç, N.; Sarı, A; Bozca, B.C; Aksu, K.; Karadağ, Ö; Alibaz‐Öner, F.; Direskeneli, H. (Wiley, 2020-12-01)
      The aim of the present study was to examine the effects of age on mucocutaneous activity by using moderation analysis in Behçet’s syndrome (BS). In this cross‐sectional study, 887 BS patients (female : male, 481:406; mean ...
    • Molecular And Clinical Spectrum Of Type I Plasminogen Deficiency: A Series Of 50 Patients 

      Tefs, Katrin; Gueorguieva, Maria; Klammt, Juergen; Allen, Carl M.; Aktas, Dilek; Anlar, Fehim Y.; Aydogdu, Sultan D.; Brown, Deborah; Ciftci, Ergin; Contarini, Patricia; Dempfle, Carl-Erik; Dostalek, Miroslav; Eisert, Susanne; Gokbuget, Aslan; Gunhan, Omer; Hidayat, Ahmed A.; Hugle, Boris; Isikoglu, Mete; Irkec, Murat; Joss, Shelagh K.; Klebe, Sonja; Kneppo, Carolin; Kurtulus, Idil; Mehta, Rakesh P.; Ornek, Kemal; Schneppenheim, Reinhard; Seregard, Stefan; Sweeney, Elizabeth; Turtschi, Stephanie; Veres, Gabor; Zeitler, Petra; Ziegler, Maike; Schuster, Volker (Amer Soc Hematology, 2006)
      Severe type I plasminogen (PLG) deficiency has been causally linked to a rare chronic inflammatory disease of the mucous membranes that may be life threatening. Here we report clinical manifestations, PLG plasma levels, ...
    • Molecular Approaches To Diagnose Diamond-Blackfan Anemia: The Eurodba Experience 

      Da Costa, Lydie; O'Donohue, Marie-Francoise; van Dooijeweert, Birgit; Albrecht, Katarzyna; Unal, Sule; Ramenghi, Ugo; Leblanc, Thierry; Dianzani, Irma; Tamary, Hannah; Bartels, Marije; Gleizes, Pierre-Emmanuel; Wlodarski, Marcin; MacInnes, Alyson W. (Elsevier Science Bv, 2018)
      Diamond-Blackfan anemia (DBA) is a rare congenital erythroblastopenia and inherited bone marrow failure syndrome that affects approximately seven individuals in every million live births. In addition to anemia, about 50% ...
    • Molecular Basis Of Hereditary C1Q Deficiency Associated With Sle And Iga Nephropathy In A Turkish Family 

      Topaloglu, R; Bakkaloglu, A; Slingsby, JH; Mihatsch, MJ; Pascual, M; Norsworthy, P; Morley, BJ; Saatci, U; Schifferli, JA; Walport, MJ (Elsevier Science Inc, 1996)
      Two siblings (case 1 and case 2) with homozygous C1q deficiency are described. Both presented with a photosensitive rash, and during follow-up case one developed SLE with nephrotic range proteinuria. Case 2 had microscopic ...
    • Molecular Cytogenetic Analysis And Resequencing Of Contactin Associated Protein-Like 2 In Autism Spectrum Disorders 

      Bakkaloglu, Betul; O'Roak, Brian J.; Louvi, Angeliki; Gupta, Abha R.; Abelson, Jesse E.; Morgan, Thomas M.; Chawarska, Katarzyna; Klin, Ami; Ercan-Sencicek, A. Gulhan; Stillman, Althea A.; Tanriover, Gamze; Abrahams, Brett S.; Duvall, Jackie A.; Robbins, Elissa M.; Geschwind, Daniel H.; Biederer, Thomas; Gunel, Murat; Lifton, Richard P.; State, Matthew W. (Cell Press, 2008)
      Autism spectrum disorders (ASD) are a group of related neurodevelopmental syndromes with complex genetic etiology.(1) We identified a de novo chromosome 7q inversion disrupting Autism susceptibility candidate 2 (AUTS2) and ...
    • Molecular Diagnosis Of Shwachman-Diamond Syndrome Presenting With Pancytopenia At An Early Age: The First Report From Turkey 

      Gokce, Muge; Tuncer, Murat; Cetin, Mualla; Gumruk, Fatma (Springer India, 2013)
      A three-month-old boy presented with growth failure, skeletal abnormalities, otitis media and pancytopenia. Exocrine pancreatic insufficiency was confirmed by low levels of fecal elastase. He was diagnosed as Shwachman-Diamond ...
    • Molecular Management Of Chronic Lymphocytic Leukemia: Towards A Chemotherapy-Free Approach 

      Sayinalp, Nilgun; Haznedaroglu, Ibrahim C. (Akad Doktorlar Yayınevi, 2016)
      B-cell receptor (BCR) signaling is implicated as a pivotal pathway in tumorigenesis in B-cell malignancies. The inhibitors of Bruton's tyrosine kinase (BTK) and phosphatidylinositide 3-kinase-delta (PI3K), modulating BCR ...
    • Molecular Screening Of Adamtsl2 Gene In 33 Patients Reveals The Genetic Heterogeneity Of Geleophysic Dysplasia 

      Allali, Slimane; Le Goff, Carine; Pressac-Diebold, Isabelle; Pfennig, Gwendoline; Mahaut, Clementine; Dagoneau, Nathalie; Alanay, Yasemin; Brady, Angela F.; Crow, Yanick J.; Devriendt, Koen; Drouin-Garraud, Valerie; Flori, Elisabeth; Genevieve, David; Hennekam, Raoul C.; Hurst, Jane; Krakow, Deborah; Le Merrer, Martine; Lichtenbelt, Klaske D.; Lynch, Sally A.; Lyonnet, Stanislas; MacDermot, Kay; Mansour, Sahar; Megarbane, Andre; Santos, Heloisa G.; Splitt, Miranda; Superti-Furga, Andrea; Unger, Sheila; Williams, Denise; Munnich, Arnold; Cormier-Daire, Valerie (B M J Publishing Group, 2011)
      Background Geleophysic dysplasia (GD, OMIM 231050) is an autosomal recessive disorder characterised by short stature, small hands and feet, stiff joints, and thick skin. Patients often present with a progressive cardiac ...
    • Monitoring Achilles Enthesitis In Ankylosing Spondylitis During Tnf-Alpha Antagonist Therapy: An Ultrasound Study 

      Aydin, Sibel Zehra; Karadag, Omer; Filippucci, Emilio; Atagunduz, Pamir; Akdogan, Ali; Kalyoncu, Umut; Grassi, Walter; Direskeneli, Haner (Oxford Univ Press, 2010)
      Objective. Enthesitis is considered as the primary anatomical lesion in ankylosing spondylitis (AS). Therapeutic effects of TNF-alpha antagonist treatments for enthesitis on imaging changes are still limited to case reports ...
    • Monitoring The Response To Tyrosine Kinase Inhibitor (Tki) Treatment In Chronic Myeloid Leukemia (Cml) 

      Haznedaroglu, Ibrahim C. (2014)
      The aim of oral tyrosine kinase inhibitor (TKI) treatment in chronic myeloid leukemia (CML) is to get ideal hematological, cytogenetic, molecular responses at the critical time points. The depth of the response obtained ...
    • Monoclonal Antibodies For Chronic Pain: A Practical Review Of Mechanisms And Clinical Applications 

      Yeh, Ju-Fen; Akinci, Aysen; Al Shaker, Mohammed; Chang, Ming Hong; Danilov, Andrei; Guillen, Rocio; Johnson, Kirk W; Kim, Yong-Chul; El-Shafei, Ahmed A; Skljarevski, Vladimir; Dueñas, Héctor J; Tassanawipas, Warat (2017)
      Context Monoclonal antibodies are being investigated for chronic pain to overcome the shortcomings of current treatment options. Objective To provide a practical overview of monoclonal antibodies in clinical development ...
    • Morbidity And Mortality Characteristics Of Infants Hospitalized In The Pediatrics Department Of The Largest Turkish Military Hospital In 2001 

      Kilic, S; Tezcan, S; Tascilar, ME; Cakir, B; Aydin, HI; Hasde, M; Gokcay, E (Assn Military Surg Us, 2005)
      A descriptive study was conducted in the pediatric inpatient unit of Gulhane Military Medical Academy, to investigate the morbidity and mortality characteristics of 532 infants hospitalized between January 1 and December ...
    • Morphological And Mechanical Properties Of Plantar Fascia And Intrinsic Foot Muscles In Individuals With And Without Flat Foot 

      Tas, Serkan; Unluer, Nezehat Ozguel; Korkusuz, Feza (Sage Publications Inc, 2018)
      Purpose: Many musculoskeletal disorders are associated with over-pronated foot and decreased medial longitudinal arch (MLA) height. Foot intrinsic muscles and plantar fascia (PF) are the primary structures that support ...
    • Morphometric Assessment Of Corpus Callosum And Cerebral Hemispheres With Magnetic Resonance Imaging 

      Kocabiyik, Necdet; Kilic, Cenk; Baykal, Baris; Tunali, Selcuk; Yalcin, Bulent; Bulakbasi, Nail; Ozan, Hasan; Akyol, Mesut (Aves Yayincilik, Ibrahim Kara, 2010)
      Objective: In this study, our purpose was to assess the relationship between handedness, footedness and the morphological differences of certain intracranial structures on MR images. Material and Methods: 63 healthy male ...
    • Mortality Indicators In Community-Acquired Pneumonia Requiring Intensive Care In Turkey 

      Erdem, Hakan; Turkan, Hulya; Cilli, Aykut; Karakas, Ahmet; Karakurt, Zuhal; Bilge, Ugur; Yazicioglu-Mocin, Ozlem; Elaldi, Nazif; Adiguzel, Nalan; Gungor, Gokay; Tasci, Canturk; Yilmaz, Gulden; Oncul, Oral; Dogan-Celik, Aygul; Erdemli, Ozcan; Oztoprak, Nefise; Tomak, Yakup; Inan, Asuman; Karaboga, Burcu; Tok, Demet; Temur, Sibel; Oksuz, Hafize; Senturk, Ozgur; Buyukkocak, Unase; Yilmaz-Karadag, Fatma; Ozcengiz, Dilek; Turker, Turker; Afyon, Murat; Samur, Anil Aktas; Ulcay, Asim; Savasci, Umit; Diktas, Husrev; Ozgen-Alpaydin, Aylin; Kilic, Erol; Bilgic, Hayati; Leblebicioglu, Hakan; Unal, Serhat; Sonmez, Guner; Gorenek, Levent (Elsevier Sci Ltd, 2013)
      Background: Severe community-acquired pneumonia (SCAP) is a fatal disease. This study was conducted to describe an outcome analysis of the intensive care units (ICUs) of Turkey. Methods: This study evaluated SCAP cases ...
    • Mortality Indicators In Pneumococcal Meningitis: Therapeutic Implications 

      Erdem, Hakan; Elaldi, Nazif; Oztoprak, Nefise; Sengoz, Gonul; Ak, Oznur; Kaya, Selcuk; Inan, Asuman; Nayman-Alpat, Saygin; Ulu-Kilic, Aysegul; Pekok, Abdullah Umut; Gunduz, Alper; Gozel, Mustafa G.; Pehlivanoglu, Filiz; Yasar, Kadriye; Yilmaz, Hava; Hatipoglu, Mustafa; Cicek-Senturk, Gonul; Akcam, Fusun Z.; Inkaya, Ahmet C.; Kazak, Esra; Sagmak-Tartar, Ayse; Tekin, Recep; Ozturk-Engin, Derya; Ersoy, Yasemin; Sipahi, Oguz Resat; Guven, Tumer; Tuncer-Ertem, Gunay; Alabay, Selma; Akbulut, Ayhan; Balkan, Ilker I.; Oncul, Oral; Cetin, Birsen; Dayan, Saim; Ersoz, Gulden; Karakas, Ahmet; Ozgunes, Nail; Sener, Alper; Yesilkaya, Aysegul; Erturk, Ayse; Gundes, Sibel; Karabay, Oguz; Sirmatel, Fatma; Tosun, Selma; Turhan, Vedat; Yalci, Aysun; Akkoyunlu, Yasemin; Aydin, Emsal; Diktas, Husrev; Kose, Sukran; Ulcay, Asim; Seyman, Derya; Savasci, Umit; Leblebicioglu, Hakan; Vahaboglu, Haluk (Elsevier Sci Ltd, 2014)
      Background: The aim of this study was to delineate mortality indicators in pneumococcal meningitis with special emphasis on therapeutic implications. Methods: This retrospective, multicenter cohort study involved a 15-year ...
    • Mortality Related Factors In Patients Requiring Hospitalization For Influenza Like Illness 

      Ozisik, Lale; Durusu Tanriover, Mine; Ciblak Akcay, Meral; Yuntcu, Kubra; Unal, Serhat; Badur, Selim; Cakir, Banu (Ankara Microbiology Soc, 2017)
      The knowledge about the viral etiologies causing respiratory disease in adults is limited. Viral respiratory diseases may lead deterioration in certain patient populations. The aim of this study was to determine the viral ...