Kanserden Sağ Kalan Bireylere Uygulanan Randomize Kontrollü Psikososyal Müdahalelerin Psikolojik Sağlamlık, Travma Sonrası Büyüme ve Anlam Bulma Düzeyi Üzerine Etkisi: Bir Sistematik Derleme ve Meta-Analiz Çalışması

Abstract

This systematic review and meta-analysis was conducted to determine the effects of randomized controlled trials of psychosocial interventions on resilience, posttraumatic growth, and meaning in cancer survivors. CINAHL Plus with Full Text (EBSCOhost), CENTRAL, Pubmed and WOS Core Collection databases were searched with no publication date or language restrictions. During the study selection process, non-English studies were excluded from the review. The review included 14 randomized controlled trials involving 1801 participants. 10 of 14 studies reporting posttraumatic growth and meaning outcomes were also involved in quantitative analysis. The effects of psychosocial interventions on resilience could not be pooled since there were a limited number of included studies. Study selection, data extraction, risk of bias assessment, and certainty of evidence assessment were carried out in line with the standard methods recommended in the “Cochrane Handbook for Systematic Reviews of Interventions”. The overall risk of bias was judged as “some concerns” or “high” for all but one study. The pooled results suggested a small, beneficial effect in favor of psychosocial interventions on meaning from pre-intervention to immediately post-intervention (Cohen’s d = -0,298, %95 CI: -0,518 - -0,077; p = 0.008; I2 = 0%; low certainty of evidence). However, the meta-analysis involving the change in meaning score from pre-intervention to the longest follow-up found that this effect was not sustained. Results also indicated no significant difference for posttraumatic growth between psychosocial interventions and routine care. The findings reveal that the effects of psychosocial interventions on all outcomes are uncertain since the certainty of the evidence ranges from “low” to “very low”, and additional evidence is needed. Future randomized trials of high methodological quality are warranted to meet the robust effects of psychosocial interventions in cancer survivors.