Konu "Tıp" için Kök Hücre Araştırma ve Uygulama Merkezi (PEDISTEM) listeleme
Toplam kayıt 5, listelenen: 1-5
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Hfe H63D Mutation Frequency Shows An Increase In Turkish Women With Breast Cancer
(BioMed Central, 2006)Background The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular ... -
Lactobacillus Rhamnosus Could Inhibit Porphyromonas Gingivalis Derived Cxcl8 Attenuation
(Scientific Electronic Library Online, 2016)An increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. P. gingivalis has been noted to have ... -
Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Immune and Lysosomal Enzyme Deficiencies
(CyberLeninka, 2016)Rare diseases affect millions of people worldwide. Many of those are inherited disorders resulting in chronic disability and requiring cost-intensive care. Hematopoietic stem cell gene therapy has been developed over more ... -
Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Metabolic Disorders
(Mary Ann Liebert, Inc, 2014)After more than 20 years of development, lentiviral hematopoietic stem cell gene therapy has entered the stage of initial clinical implementation for immune deficiencies and storage disorders. This brief review summarizes ... -
Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of Mngie
(Elsevier, 2018)Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder caused by thymidine phosphorylase (TP) deficiency resulting in systemic accumulation of thymidine (d-Thd) and deoxyuridine ...