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Sanal Ligand Taraması Yöntemi ile Nikotinik Asetilkolin Antagonistlerinin Tasarımı
(Fen Bilimleri Enstitüsü, 2018)
A total of 14.8 million people in Turkey (27.1%) use tobacco products. Nicotine dependence is the first cause of continued smoking behavior and overall failure of treatment interventions. Nicotine, an alkaloid derived from ...
Dopamin 2 Reseptör Antagonisti Olarak Bazı Fitokimyasalların Antipsikotik Aktivitesinin Moleküler Doking Yöntemi ile Araştırılması
(Fen Bilimleri Enstitüsü, 2021)
Schizophrenia is a psychotic disorder characterized by delusions, hallucinations, disturbances of perception, thought, and behavior. Schizophrenia is caused by overactivation of the dopamine D2 receptor.
Currently, dopamine ...
Moleküler Doking ve Farmakokinetik Yöntemler ile Sars-coV-2 Ana Proteaz 3CLPRO için Potansiyel İnhibitörlerin Araştırılması
(Fen Bilimleri Enstitüsü, 2023)
On December 30, 2019, a new virus emerged in the city of Wuhan, Hubei province of China,
and quickly spread to more than 150 countries [2]. As a result of the studies carried out by
scientists on this new virus, it was ...