0-3 Yaş Atopik Dermatitli Çocuk Hastalarda ve Ebevenylerinde Uyku Kalitesinin Değerlendirilmesi

Abstract

Tol K., Evaluation of sleep quality in children aged 0-3 years with atopic dermatitis and their parents. Hacettepe University Faculty of Medicine, Department of Child Health and Diseases, Specialization Thesis. Ankara, 2023. Atopic dermatitis is one of the most common chronic inflammatory skin diseases in childhood and is commonly associated with sleep disturbance. BISQ-R a sensitive and specific tool for identifying sleep problems for children aged 0-36 months which is validated in many centers. In this study, it was aimed to evaluate the sleep quality of patients with AD and their parents who admitted to Hacettepe University Pediatric Allergy Polyclinic and to show its relationship with the severity of the disease. The study included 92 patients aged 0-3 years who were evaluated as AD according to the Hanifin-Rajka criteria and 86 healthy controls with typical development who had no sleep problems between May 15, 2022 and August 10, 2022. There was no difference in age and gender between the patients (n=92, male [66.3%], age median [IQR] 7 [5-11] months) and control group (p>0.05). The demographic, clinical, laboratory characteristics and the severity of the disease with the Objective SCORAD index of patients were evaluated. In addition, the BISQ-R, which evaluates the sleep quality of the patients, and PSQI, which evaluates the sleep quality of the parents, were filled by the parents (mother). BISQ-R infant sleep score (p<0.001), BISQ-R total score (p<0.001) and BISQ-R parental perception score (p=0.001) of patients were lower than healthy controls. 71.7% of the patients' parents had poor sleep quality in PUKI. Similarly, atopic patients had lower BISQ-R infant sleep score (p=0.008) and BISQ-R total score (p=0.015) than those without atopy; VAS scores did not differ between groups. BISQ-R infant sleep score (r=-0.205; p<0.001) of patients correlated with disease severity. BISQ-R infant sleep score (r=-0.426; p<0.001) and BISQ-R total score (r=-0.388; p<0.001) and BISQ-R parental perception score (r=-0.352; p=0.001) of patients were statistically significant correlation with PSQI. Atopic dermatitis patients and their families face different levels of sleep disturbance, and the presence of atopy can worsen this situation even more. Larger and multicenter studies are needed to identify interventions that will improve the sleep quality of patients.