Gümüş İçeren Nanopartiküller Tuzlar ile Yüklü Montmorillonit Esaslı Nanokompozitlerin Geliştirilmesi ve Antikanser Özellikleri

Abstract

Recently, the attentions of many researchers were focused on PLA and functional alternating copolymers based nanocomposites. PLA is of significant interest in bioengineering applications such as wound closure, tissue culture and controlled release. Preparation of PLA/clay nanocomposites by using solution blending method was also reported. Although the most promising reaction for the synthesis of polymer/clay nanocomposites is the intercalative (co)polymerization of various functional monomers, the interlamellar graft copolymerization of lactic acid monomer onto alternating copolymers of maleic anhydride in the presence of organoclay has been not investigated. Complex-radical interlamellar solution copolymerization of maleic anhydride and itaconic acid with butyl methacrylate in the presence of reactive and non-reactive organoclays was the subject of recent publications of our group. This thesis presens a new appoach for the synthesis and characterization of functional copolymer-g-biopolymer in two dimensional layered silicate nanocomposites and their Ag+ -carried nanohybrids. Novel bioengineering functional copolymer [poly(maleic anhydride-alt-1-octadecene)-g-biopolymer (poly(L-lactic acid)] layered silicate (octadecylamine-montmorillonite, ODA-MMT and dimethyldidodecyl ammonium-MMT, DMDA-MMT) nanocomposites and their Ag+ -carried derivatives were synthesized by catalytic interlamellar bulk graft copolymerization of L-lactic acid (LA) monomer (or LA-Ag+ ) onto alternating copolymer as a reactive matrix polymer in the presence of preintercalated LA…MMT organoclays (ODA-MMT and DMDA-MMT) complexes as nanofillers .