Browsing Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu by Title
Now showing items 46-65 of 155
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Evaluation of Cytotoxicity and Genotoxicity of Eugenol in Lymphocytes
(Sağlık Bilimleri Enstitüsü, 2014)Eugenol is a volatile phenolic constituent of clove essential oil obtained from Eugenia Caryophyllata buds and leaves. It is a functional ingredient in numerous products. It has been used in the pharmaceutical and cosmetics ... -
Farelerde lipopolisakkarit ile indüklenen solunum yolu inflamasyonunda mitokondriye hedeflendirilmiş yavaş hidrojen sülfür salıveren AP39'un ve nitrik oksit sentaz inhibitörü asimetrik dimetil arjinin (ADMA)'nın etkilerinin araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)In this study, the effects of mitochondria-targeted slow H2S releasing donor AP39 on lipopolysaccharide (LPS)-induced airway inflammation were investigated in in vitro and in vivo models. In in vitro model tracheal rings ... -
Febril Nötropeni Gelişim Riski Olan ve Granülosit Koloni Stimüle Edici Faktör (G-Csf) Kullanan Kanser Hastalarının Patıent Rısk Score (Prs) ile Takibi ve Yan Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-06)Febrile neutropenia is the most important dose-limiting side effect of chemotherapy. Although the international treatment guidelines recommend prophylactic use of G-CSF in chemotherapy protocols with a risk of febrile ... -
Flurbiprofenin Sitotoksik, Genotoksik ve Apoptotik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018-11-02)B Bakir, E., Evaluation of Cytotoxic, Genotoxic and Apoptotic Effect of Flurbiprofen, Hacettepe Un¬vers¬ity Graduate School Health Sciences Pharmacy Department of Pharmaceutical Toxicology Doctor of Phi¬losophy Thes¬is, ... -
Genisteinin Dna Hasarı Üzerindeki Etkilerinin Kolon Kanseri Hücrelerinde Tek Hücre Jel Elektroforez (Comet) Yöntemiyle Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Çal Doğan, T., Evaluation of The Effects of Genistein on DNA Damage by Single Cell Gel Electrophoresis (Comet) in Colon Cancer Cells, Hacettepe University Institute of Health Sciences Doctor of Philosophy Thesis on ... -
Gentiana olivieri Griseb.’in Nöroprotektif Etkisi
(Sağlık Bilimleri Enstitüsü, 2024-06-25)The genus Gentiana has 400 species in the world and 12 species in Türkiye, and plants belonging to this genus have had a wide range of uses in folk medicine for many years. Gentiana olivieri Griseb. used in Southeastern ... -
Geriatri Polikliniği Ve Huzurevi Hastalarının STOPP/START ve MAI Kriterleri ile Değerlendirilmesi ve Müdahalelerin Yapılmasında Klinik Eczacının Rolü
(Sağlık Bilimleri Enstitüsü, 2017-07-13)In this thesis, second version of "Screening Tool of Older People’s Potentially Inappropriate Prescriptions (STOPP)” and " Screening Tool to Alert Doctors to Right Treatment (START)” criteria have been used to determine ... -
Halk İlacı Olarak Kullanılan Peganum harmala L. (Üzerlik) Tohumları Üzerinde İlaç Hammaddesi Yönünden Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2022)Peganum harmala L., which is the only species representing the genus Peganum in Turkey, is known as “üzerlik” and is widely used as folk medicine. It is known that pharmacological studies performed on the plant support ... -
Halk İlacı ve Gıda Olarak Kullanılan Prunus Mahaleb L. Tohum ve Meyve Kabuklarında Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2020)Prunus mahaleb L. (syn. Cerasus mahaleb L. Mill.), a member of medicinal plant kingdom, is known as mahlep, mehlep, idris ağac or pis agac and the seeds used as food and exported. In the present study, In our thesis, ... -
Hashimoto Tiroiditinde Selenyum ve Selenoprotein Düzeyleri ile Oksidatif Stres Biyogöstergelerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Hashimoto's thyroiditis (HT) is an autoimmune disease of thyroid gland. In the course of the disease, thyroid gland is attacked by a variety of cell- and antibody-mediated immune processes. It is reported that high iodine ... -
Hekzahidrokinolin Türevlerinin Sentezi, Sitotoksik Özelliklerinin, ROS Oluşturma Potansiyellerinin ve Enflamasyon Mediyatörleri Üzerine Etkilerinin İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this study, novel 24 compounds with alkyl 2,6,6-trimethyl-4-(disubstituted phenyl)-5-oxo- 1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (Compound 1a-1f, 2a-2f, 3a-3f and 4a-4f) structure which is expected to show ... -
Hepatit B ve C Virüsü ile Enfekte Hastaların Tedavisinde İlaç Kaynaklı Sorunlar
(Sağlık Bilimleri Enstitüsü, 2018)Hepatitis B and C are the leading cause of cirrhosis and hepatocellular carcinoma. A low diagnosis rate and poor access to clinical care are a major risks in hepatitis B and C‐related morbidity and mortality. Lack of ... -
In Silico Toksikoloji Yöntemleri ve Uygulamaları Üzerine Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2024)The use of computer-assisted toxicology methods (in silico toxicology, computer-based toxicology etc.) in predicting preclinical toxicological endpoints, clinical side effects, and the metabolism of pharmaceutical ... -
Inula Fragılıs Boıss. & Hausskn. Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2023)Uzun, K., Pharmacognosical studies on Inula fragilis Boiss. & Hausskn., Hacettepe University, Graduate School of Health Sciences, Pharmacognosy Program, PhD Thesis, Ankara, 2023. Inula L. (Asteraceae) species are rich in ... -
Investigation of Intracellular Mechanisms of Sphingosine-1-Phosphate (S1P)-Induced Contractions in Detrusor Smooth Muscle of Rats having Cyclophosphamide-Induced Cystitis
(Sağlık Bilimleri Enstitüsü, 2017)Anjum I., Investigation of Intracellular Mechanisms of Sphingosine-1-Phosphate (S1P)-Induced Contractions in Detrusor Smooth Muscle of Rats having Cyclophosphamide-Induced Cystitis, Hacettepe University, Institute of Health ... -
Investigation of Possible Protective Effects of Certain Xenobiotics on Aluminum Toxicity in SH-SY5Y Cell Line
(Sağlık Bilimleri Enstitüsü, 2023-11-16)Aluminum, a neurotoxic metal, is widely present in our daily lives, exposing us extensively. Aluminum exposure is a potential Alzheimer's risk factor, with no cure yet. Researchers are actively seeking new treatments or ... -
Isolatıon of Potentıal Drug Candıdate Molecules from Rumex Acetosella L. and in Sılıco, in Vıtro Researches on Those Molecules
(Sağlık Bilimleri Enstitüsü, 2018)Ozenver, N., Isolation of Potential Drug Candidate Molecules From Rumex acetosella L. and In Silico, In Vitro Researches on Those Molecules, Hacettepe University, Institute of Health Sciences, Pharmacognosy Program, Doctor ... -
İç Hastalıkları Servislerinde Yatan Hastalarda Uygun Olmayan Endikasyonlarda Oral Proton Pompası İnhibitörleri Kullanımının Tespit Edilmesi ve Hasta Uyuncunun Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)The use of unnecessary proton pump inhibitors (PPIs) is very common in the world and in our country also. This situation increases the risk of many adverse reactions and drug interactions. For this reason, in order to ... -
İlaç Hammaddesi Kaynağı Bazı Scutellaria L. Türleri Üzerinde Farmakognozik Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2018-01)Genus Scutellaria (Lamiaceae), which includes about 350 species in worldwide, is widespread in Europe, America and East Asia. It is represented by 16 species in the flora of Turkey. Scutellaria species are the most popular ... -
İmidakloprid ve Asetamipridin İn Vitro Sistemler Üzerindeki Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022-06-27)Neonicotinoids, which have received attention in recent years due to their toxic effects on non-target organisms, particularly bees, are a nicotine-derived insecticide group that is widely used in many countries, including ...