Bölüm "Farmakoloji" Eczacılık Meslek Bilimleri Bölümü Makale Koleksiyonu için listeleme
Toplam kayıt 18, listelenen: 1-18
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Comparison Of Antioxidant Activities Of Aminoguanidine, Methylguanidine And Guanidine By Luminol-Enhanced Chemiluminescence
(Wiley, 1998)1 The objective of this study was to investigate the ability of aminoguanidine, methylguanidine and guanidine to inhibit free radicals or metabolites generated by either stimulated human leucocytes or cell-free systems ... -
Cyp2C19 Genotype Does Not Represent A Genetic Predisposition In Idiopathic Systemic Lupus Erythematosus
(British Med Journal Publ Group, 1999)Background-The aetiology of systemic lupus erythematosus (SLE) is still unknown. In several cases, however, chemicals or drugs were identified as aetiological agents and associations with certain phenotypes of drug ... -
Endocannabinoid System In The Airways
(2019)Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of ... -
Infliximab Alleviates The Mortality, Mesenteric Hypoperfusion, Aortic Dysfunction, And Multiple Organ Damage In Septic Rats
(Canadian Science Publishing, Nrc Research Press, 2017)Tumor necrosis factor-alpha (TNF-alpha) is a pivotal mediator that triggers inflammatory process, oxidative stress, and multiple organ injury in sepsis. We investigated the effects of infliximab on survival, mesenteric ... -
Inhibitory Effect Of The Methanolic Extract Of Verbascum Latisepalum Hub.-Mor. On Endothelium-Dependent Relaxation In Rat Thoracic Aorta
(Walter De Gruyter Gmbh, 2014)The leaves and flowers of Verbascum species are used to treat respiratory disorders, haemorrhoids, rheumatic pain, and wounds as well as for the treatment of eczema and other types of inflammatory skin conditions in ... -
Interactions Of Aromatase And Seladin-1: A Neurosteroidogenic And Gender Perspective
(2019)Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key enzyme that catalyzes estrogen biosynthesis from androgen ... -
Investigation of 1377C/T Polymorphism of the Toll-Like Receptor 3 Among Patients with Chronic Hepatitis B
(Canadian Science Publishing, Nrc Research Press, 2016)The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis ... -
Investigation of Serotonin Receptors in the Isolated Penile Bulb of Rats
(Nature Publishing Group, 2006)The aim of this study was to investigate serotonin (5-HT) receptors in the penile bulb, which have been suggested to play a role in penile erection. Serotonin (10(-7)-3 x 10(-4) M) contracted penile bulbs in a concentrat ... -
Involvement of Rho Kinase and Protein Kinase C in Carbachol-Induced Calcium Sensitization in Beta-Escin Skinned Rat and Guinea-Pig Bladders
(Wiley, 2006)1 The signal transduction pathways involved in carbachol (CCh)-induced calcium sensitization in beta-escin permeabilized rat and guinea-pig bladder smooth muscles were investigated and the results were compared with ... -
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ... -
Postpubertal Decrease in Hippocampal Dendritic Spines of Female Rats
(Academic Press Inc Elsevier Science, 2008)Hippocampal dendritic spine and synapse numbers in female rats vary across the estrous cycle and following experimental manipulation of hormone levels in adulthood. Based on behavioral studies demonstrating that learning ... -
Resveratrol Prevents Dendritic Cell Maturation In Response To Advanced Glycation End Products
(2013)Advanced glycation end products (AGEs), generated through nonenzymatic glycosylation of proteins, lipids, and nucleic acids, accumulate in the body by age thus being considered as biomarkers of senescence. Senescence is ... -
Rostral Ventrolateral Medullary But Not Medullary Lateral Tegmental Field Neurons Mediate Sympatho-Sympathetic Reflexes in Cats
(Amer Physiological Soc, 2010)Barman SM, Orer HS. Rostral ventrolateral medullary but not medullary lateral tegmental field neurons mediate sympatho-sympathetic reflexes in cats. Am J Physiol Regul Integr Comp Physiol 299: R1269-R1278, 2010. First ... -
Sodium Nitrite Provides Angiogenic And Proliferative Effects In Vivo And In Vitro
(2015)Background Angiogenesis is the formation of new blood vessels from pre-existing vasculature. Many factors and substances may stimulate angiogenesis and exhibit proliferative effect. In this study, we aimed to investigate ... -
Soluble Guanylyl Cyclase Activators Increase The Expression Of Tolerance To Morphine Analgesic Effect
(Comenius Univ, 2014)Objectives: It is aimed to investigate the effects of guanylyl cyclase activation and inhibition on acute morphine antinociception and the development of tolerance to its effect. Background: Nitric oxide-soluble guanylyl ... -
Tpc2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (Naadp)- And Agonist-Evoked Contractions Of Smooth Muscle
(2010)Agonists such as those acting at muscarinic receptors are thought to induce contraction of smooth muscle primarily through inositol 1,4,5-trisphosphate production and release of Ca2+ from sarcoplasmic reticulum. However, ...