dc.contributor.author | Aksoy, Evrim Kahramanoğlu | |
dc.contributor.author | Sapmaz, Ferdane Pirinççi | |
dc.contributor.author | Doğan, Özlem | |
dc.contributor.author | Göktaş, Zeynep | |
dc.contributor.author | Uzman, Metin | |
dc.contributor.author | Nazlıgül, Yaşar | |
dc.date.accessioned | 2021-06-09T06:35:50Z | |
dc.date.available | 2021-06-09T06:35:50Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1895-5770 | |
dc.identifier.uri | http://dx.doi.org/10.5114/pg.2019.83425 | |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444112/ | |
dc.identifier.uri | http://hdl.handle.net/11655/24843 | |
dc.description.abstract | Introduction Interleukin-35 (IL-35) is a newly defined potent anti-inflammatory cytokine that is predominantly produced by regulatory T cells, and pentraxin-3 belongs to the acute-phase proteins. Aim To measure the serum IL-35 and pentraxin-3 levels in the early phase of mild acute pancreatitis (AP). Material and methods Eighty-three patients with mild AP and 30 healthy controls were included in the study. The serum levels of IL-35 and pentraxin-3 were measured by enzyme-linked immunosorbent assay upon admission and at the 48th hour after diagnosis. Results The mean value of serum IL-35 levels in patients with mild acute pancreatitis at admission was 5.91 ng/ml (4.21–7.90) and was significantly lower than those in healthy controls (25.53 ng/ml (12.79–54.73, p < 0.001)) and 48-hour value were (6.79 ng/ml (4.42–9.62) (p = 0.015)). The mean value of serum pentraxin-3 levels in patients at the time of admission was 6.75 ng/ml (4.42–9.62) and there was no significant difference from healthy controls, at 7.64 ng/ml (6.58–8.62, p > 0.05). Also there was no significant difference between the mean value at admission and the mean value at 48-hour, 6.75 ng/ml (4.74–9.06, p > 0.05). Conclusions Interleukin-35 can be used in diagnosis and follow-up in patients with mild AP. | |
dc.language.iso | en | |
dc.relation.isversionof | 10.5114/pg.2019.83425 | |
dc.rights | Attribution 4.0 United States | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Serum Interleukin-35 And Pentraxin-3 Levels In Patients With Mild Acute Pancreatitis | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.relation.journal | Przegla̜D Gastroenterologiczny | |
dc.contributor.department | Beslenme ve Diyetetik | |
dc.identifier.volume | 14 | |
dc.identifier.issue | 1 | |
dc.description.index | PubMed | |
dc.description.index | WoS | |
dc.description.index | Scopus | |