Cystic Echinococcosis Cases In A Tertiary Hospital Between 2006 And 2016

Abstract

Echinococcosis is a zoonotic disease caused by Echinococcus species. Echinococcus granulosus is the most frequent factor of disease. It is the cause of significant morbidity and mortality. The aim of this study was to compare the clinic and laboratory findings in hepatic and extrahepatic involvement of hydatid cysts cases and to determine whether there was a significant difference in terms of serological, biochemical and recurrence in both group. Methods: The study was planned retrospectively. Total of 82 patients were evaluated. Patients were divided into two groups as hepatic and extrahepatic involvement. Hepatic involvement was detected in 45 patients and extrahepatic involvement was detected in 37 patients. Results: In group of hepatic involvement, 20 patients were male and 25 patients were female. The mean age of the patients was 47 years. In the laboratory examination; in 25% of patients leukocytosis and in 4% of patients eosinophilia were detected. In 8% of patients increase of globulin fraction, in 44% of patients increase of C-reactive protein (CRP), in 35% of patients increase of liver function test (LFT) or bilirubin were found. Indirect hemagglutination antibody (IHA) test was positive in 60% of patients. 20 patients had recurrence. In group of extrahepatic involvement 14 patients were male and 20 patients were female. The mean age of the patients was 48. In the laboratory examination; in 16% of patients leukocytosis and in 5% of patients eosinophilia were detected. In 8% of patients increase of globulin fraction, in 16% of patients increase of CRP, in 38% of patients increase of LFT or bilirubin were detected. In 50% of patients IHA test positivity were found. 17 patients had recurrence. Conclusion: In the group with hepatic involvement, leukocytosis, CRP increase, diabetes mellitus (DM) comorbidity, IHA test positivity and recurrence development were higher compared to the extrahepatic patients. The increase in globulin fraction, LFT or bilirubin increase, eosinophilia, gender distribution, mean age and underlying malignancy were similar in both groups. No statistically significant difference was found between the findings of the hepatic involvement and extra hepatic involvement. © 2019 Refik Saydam National Public Health Agency (RSNPHA).