Sıçan Karın Duvarında Polyglactin 910 Yama Katlanmasının Enfeksiyon ve Yama Büzüşmesi Üzerine Etkisi

Abstract

Mesh folding is commonly encountered when Polyglactin 910 mesh is used on abdominal wall for any reason. The aim of this study is to investigate the effects of folding of polyglactin 910 mesh fixed on rat abdominal wall, on surgical site infection and mesh shrinkage. Rats were divided into four groups; as control and bacteria inoculated group (Staphylococcus aureus ATCC 25923) by using single and double layer mesh. On day 18, shinkage ratio (by calculating mesh surface area), bacterial load on mesh and serum CRP and procalcitonin levels were measured. When the groups were compared, weight gain was significantly lower in bacteria inoculated groups. Mesh shrinkage was observed in all groups, being maximum in single layer control group (32.2%) and minimum in bacteria inoculated groups (19.2%). However, these differences were not statistically significant. Staphylococcus aureus load was found to be the highest in double layer mesh group and was calculated to be 4330 cFU/ml. Bacterial load was significantly different in bacteria inoculated groups. Serum C-reactive protein and procalcitonin levels were not significantly different among any groups. As a result, although not statistically significant, the higher the bacterial load; the less the mesh shrinkage and bacterial load remains higher in double layer mesh. Our results need supporting with further experimental and clinical studies.