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Tuzaklamalı İyon Hareketliliği Kütle Spektrometrisi ile İnsan İnsülini ve Analoglarının Analizi
(Fen Bilimleri Enstitüsü, 2019)
Insulin is very important for human life and highly sensitive to environmental factors. The insulin hormone that regulates the sugar in the blood is also involved in protein and fat metabolism. It can easily undergo ...
Süt Whey Proteinlerinin Kütle Spektrometrik Yöntemler N-Glikan Profillerinin Belirlenmesi
(Fen Bilimleri Enstitüsü, 2020-01)
Post-translational modifications control many biological activities and it is known that about 300 different post-translational modifications occur in protein structures. Glycosylation is one of the most common forms of ...
Polimerik Membranlardan Kontrollü İnsülin Salımının Kütle Spektrometrik Tayini
(Fen Bilimleri Enstitüsü, 2021)
The number of diabetes mellitus patients is increasing day by day in the world. This disease is caused by the failure or destruction of β cells responsible for insulin release. The most important task of the insulin hormone ...
Kefirin Fermantasyonu ve Depolanması Süreçlerinde Süt Protein N-Glikanları ve Serbest Süt Oligosakkaritleri Profillerindeki Değişimin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022-05)
Kefir is an ancient food source based on the Caucasus mountains. Kefir is mainly produced by fermentation of kefir microorganisms using cow's milk. There are many studies showing the benefits of kefir to human health. The ...
Proteinlerin Çözelti ve Gaz Fazındaki Konformasyonlarının Tuzaklı İyon Hareketliliği-Kütle Spektrometrisi Kullanılarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2022-05)
The issue on protein conformation in the gas phase has not been fully clarified yet. The protein conformation in the gas phase may be affected by conformational changes in the solution phase, which occur due to the changes ...
Proteomiks Çalışmalarında Fosfopeptitlerin Spesifik Olarak Zenginleştirilmesi ve Kütle Spektrometrisi ile Tayini için Polikatyonik Malzemelerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018)
Phosphorylation is the most common post-translational modification and is regulated by
kinase signaling pathways. Defects in this pathway may be related to various diseases such
as cancer, diabetes, chronic inflammatory ...