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dc.contributor.authorTaşdemir, Deniz
dc.contributor.authorMangalindan, Gina C
dc.contributor.authorConcepcion, Gisela P
dc.contributor.authorHarper, Mary Kay
dc.contributor.authorIrelanda, Chris M
dc.date.accessioned2019-12-16T10:09:47Z
dc.date.available2019-12-16T10:09:47Z
dc.date.issued2001
dc.identifier.issn0009-2363
dc.identifier.urihttps://doi.org/10.1248/cpb.49.1628
dc.identifier.urihttp://hdl.handle.net/11655/19970
dc.description.abstractA new purine 3,7-dimethylguanine (1) has been isolated from the marine sponge Zyzzya fuliginosa, along with the known metabolites. makaluvamines A, C, K (2-4), 4-hydroxyphenylacetic acid (5), methyl ester of 4-hydroxyphenylacetic acid (6), 4-hydroxyphenethyl alcohol (7), L-phenylalanine (8) and L-tryptophan (9). The structure of 3,7-dimethylguanine (1) was elucidated by analysis of 1D and 2D (one- and two-dimensional) NMR [HMQC (heteronuclear multiple quantum coherence), gHMBC (heteronuclear multiple bond connectivity), H-1-N-15 gHMBC] data, mass spectroscopy data, and by comparison with 3,7-dimethylisoguanine (10).
dc.language.isoen
dc.publisherPharmaceutical Soc Japan
dc.relation.isversionof10.1248/cpb.49.1628
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPharmacology & Pharmacy
dc.subjectChemistry
dc.title3,7-Dimethylguanine, A New Purine From A Philippine Sponge Zyzzya Fuliginosa
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalChemical & Pharmaceutical Bulletin
dc.contributor.departmentFarmakognozi
dc.identifier.volume49
dc.identifier.issue12
dc.identifier.startpage1628
dc.identifier.endpage1630
dc.description.indexWoS
dc.description.indexScopus


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