The Role Of Factor V Leiden In Adult Patients With Venous Thromboembolism: A Meta-Analysis Of Published Studies From Turkey

Tarih
2012Yazar
Eroglu, Aydan
Sertkaya, Durdu
Akar, Nejat
- Citations
- CrossRef - Citation Indexes: 5
- PubMed - Citation Indexes: 3
- Scopus - Citation Indexes: 7
- Captures
- Mendeley - Readers: 5
publications
0
supporting
0
mentioning
0
contrasting
0
0
0
0
0
Citing PublicationsSupportingMentioningContrasting
See how this article has been cited at scite.ai
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Üst veri
Tüm öğe kaydını gösterÖzet
Factor V Leiden (FVL) is the most common inherited risk factor for venous thromboembolism (VTE). The frequency of FVL in patients with VTE has been reported from different parts of Turkey. A meta-analysis was performed to estimate the risk of VTE associated with FVL in Turkish population. Published studies were retrieved from Pubmed and Science Citation Index/Expanded. We selected studies comparing the prevalence of FVL in patients with VTE with controls. The analysis was performed by the software comprehensive meta-analysis. The analysis consisted of 10 studies including 1202 patients with VTE and 1283 controls. The pooled frequency of FVL was significantly higher in patients with VTE (22.8%) than controls (7.6%). The pooled odds ratio (OR) was 3.4 (95% confidence interval [CI], 2.6-4.5). The study showed homogeneity (Q value, 9.955). No publication bias was observed in any comparison model. Our meta-analysis showed an association of FVL with VTE in Turkey.