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dc.contributor.authorDesteli, Guldeniz Aksan
dc.contributor.authorGultekin, Murat
dc.contributor.authorUsubutun, Alp
dc.contributor.authorYuce, Kunter
dc.contributor.authorAyhan, Ali
dc.date.accessioned2019-12-12T06:42:53Z
dc.date.available2019-12-12T06:42:53Z
dc.date.issued2010
dc.identifier.issn1477-7819
dc.identifier.urihttps://doi.org/10.1186/1477-7819-8-106
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002346/
dc.identifier.urihttp://hdl.handle.net/11655/16768
dc.description.abstractBackground Lymphadenectomy is an integral part of the staging system of epithelial ovarian cancer. However, the extent of lymphadenectomy in the early stages of ovarian cancer is controversial. The objective of this study was to identify the lymph node involvement in unilateral epithelial ovarian cancer apparently confined to the one ovary (clinical stage Ia). Methods A prospective study of clinical stage I ovarian cancer patients is presented. Patient's characteristics and tumor histopathology were the variables evaluated. Results Thirty three ovarian cancer patients with intact ovarian capsule were evaluated. Intraoperatively, neither of the patients had surface involvement, adhesions, ascites or palpable lymph nodes (supposed to be clinical stage Ia). The mean age of the study group was 55.3 ± 11.8. All patients were surgically staged and have undergone a systematic pelvic and paraaortic lymphadenectomy. Final surgicopathologic reports revealed capsular involvement in seven patients (21.2%), contralateral ovarian involvement in two (6%) and omental metastasis in one (3%) patient. There were two patients (6%) with lymph node involvement. One of the two lymph node metastasis was solely in paraaortic node and the other metastasis was in ipsilateral pelvic lymph node. Ovarian capsule was intact in all of the patients with lymph node involvement and the tumor was grade 3. Conclusion In clinical stage Ia ovarian cancer patients, there may be a risk of paraaortic and pelvic lymph node metastasis. Further studies with larger sample size are needed for an exact conclusion.
dc.relation.isversionof10.1186/1477-7819-8-106
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleLymph Node Metastasis in Grossly Apparent Clinical Stage Ia Epithelial Ovarian Cancer: Hacettepe Experience and Review of Literature
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalWorld Journal of Surgical Oncology
dc.contributor.departmentKadın Hastalıkları ve Doğum
dc.identifier.volume8
dc.identifier.startpage106
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus


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