A Novel Graft Option After Pterygium Excision: Platelet-Rich Fibrin for Conjunctivoplasty

Abstract

Purpose To compare the surgical results, complications, and recurrence rates of primary pterygium excision with conjunctival autografts (CA) vs platelet-rich fibrin (PRF) grafts. Patients and methods A total of 35 eyes of 35 patients with primary pterygium were included in the study. The patients underwent excision of pterygium followed by closure of the bare sclera by CA (group 1, n = 20) vs PRF grafts (group 2, n = 15). The PRF was generated from the patients' own whole-blood sample by centrifugation and pressing. The surgery times, intra/postoperative complications, recurrence rates of pterygium, and changes in visual acuity (VA) were evaluated and compared within groups. Results The mean follow-up period was 14.3 +/- 6.5 months (6-24 months). The mean preoperative and postoperative VAs were same (20/25) (P = 0.204). The mean surgery time was shorter in group 2 (22.1 +/- 1.9 min) compared to group 1 (33.8 +/- 7.8 min) (P = 0.001). The recurrence was observed only in one (6.6%) case of group 2, while none of the cases showed recurrence in group 1. Graft loss was observed in 2 (10%) cases in group 1, and 1 (6.6%) case in group 2. No other intra/postoperative complications such as tear in the graft, excessive bleeding, scleral necrosis, graft necrosis, pannus formation, or symblepharon occurred in both groups. Conclusions This preliminary study showed encouraging results of the application of PRF for conjuntivoplasty after pterygium excision. The use of PRF in pterygium surgery is a simple, easily applicable, and a promising method with low rates of recurrence and complications.