Basit öğe kaydını göster

dc.contributor.authorTekin, Kemal
dc.contributor.authorErol, Yasemin Ozdamar
dc.contributor.authorSargon, Mustafa Fevzi
dc.contributor.authorInanc, Merve
dc.contributor.authorOzdal, Pinar Cakar
dc.contributor.authorBerker, Nilufer
dc.date.accessioned2019-12-12T06:40:47Z
dc.date.available2019-12-12T06:40:47Z
dc.date.issued2017
dc.identifier.issn0301-4738
dc.identifier.urihttps://doi.org/10.4103/ijo.IJO_691_17
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742983/
dc.identifier.urihttp://hdl.handle.net/11655/16606
dc.description.abstractPurpose: The purpose of the study was to investigate the electron microscopic findings of the lens epithelial cells (LECs) in patients with Fuchs uveitis syndrome (FUS) who suffered from cataracts and to compare those with age-matched controls. Methods: This study was a prospective, comparative case series. The anterior lens capsules (ALC: basement membrane and associated LECs) were taken from 12 eyes of 12 cases of FUS and ten eyes of ten control patients. The ALCs were obtained from cataract surgery and prepared for transmission electron microscopy (TEM). Results: There were no statistically significant differences regarding the age or gender between the FUS group and the control group (P > 0.05). In the TEM examinations of the ALCs, all of the FUS cases revealed similar significant ultrastructural changes when compared to the control patients. In the FUS group, the LECs showed homogeneous thickening and irregularity which included some small vacuoles in different areas of the epithelial tissue. Moreover, in some areas of the LECs, widespread, oval-shaped, pigment clusters were detected. Conversely, in the control group, the LECs and all of their elements were in normal ultrastructural patterns, with the exception of some small intraepithelial vacuoles which were fewer and smaller than those in the FUS group. Conclusion: Ultrastructural analysis of the ALC of the patients with FUS disclosed some significant alterations which may be related to the summation of oxidative stress, intraocular inflammation, and iris atrophy.
dc.relation.isversionof10.4103/ijo.IJO_691_17
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleEffects Of Fuchs Uveitis Syndrome On The Ultrastructure Of The Anterior Lens Epithelium: A Transmission Electron Microscopic Study
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalIndian Journal of Ophthalmology
dc.contributor.departmentGöz Hastalıkları
dc.identifier.volume65
dc.identifier.issue12
dc.identifier.startpage1459
dc.identifier.endpage1464
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus


Bu öğenin dosyaları:

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster