dc.contributor.author | Oc, Mehmet | |
dc.contributor.author | Ucar, Halil Ibrahim | |
dc.contributor.author | Pinar, Asil | |
dc.contributor.author | Akbulut, Birkan | |
dc.contributor.author | Oc, Bahar | |
dc.contributor.author | Akinci, Seda Banu | |
dc.contributor.author | Akyon, Yakut | |
dc.contributor.author | Kanbak, Meral | |
dc.contributor.author | Boke, Erkmen | |
dc.contributor.author | Dogan, Riza | |
dc.date.accessioned | 2019-12-12T06:24:51Z | |
dc.date.available | 2019-12-12T06:24:51Z | |
dc.date.issued | 2007 | |
dc.identifier.issn | 0379-5284 | |
dc.identifier.uri | https://doi.org/ | |
dc.identifier.uri | http://hdl.handle.net/11655/16214 | |
dc.description.abstract | Objective: To examined the pre- and post-operative anti-HSP60 antibodies of serum from patients in preoperative sinus rhythm. Methods: We prospectively studied 45 consecutive patients admitted for elective CABG from 2004 to 2005. We randomly selected 10 patients developing AF (study sample [Group A]) and 10 postoperative patients without AF (control [Group B]. The study took place at the Department of Cardiovascular Surgery, Hacettepe University, Ankara, Turkey. Results: Anti-HSP60 IgG value was 27.76 +/- 12.69 absorbance units (AU) in Group A preoperatively and decreased to 13.73 +/- 5.51 AU postoperatively. Controversially, preoperative value of anti-HSP60 IgG was 9.94 +/- 2.92 AU and decreased to 6.72 +/- 1.89 AU, postoperatively in Group B. Statistical analysis showed significant difference regarding preoperative anti-HSP60 IgG levels in Group A compared to Group B, which might be interpreted as an association between postoperative AF and preoperative levels of anti-HSP60 IgG. Conclusion: We provide the first evidence demonstrating the association of pre- and post-operative circulating anti-HSP60 antibodies with postoperative AF. These results suggest that serum HSP60 antibody levels may be a marker for subsequent development of AF. | |
dc.language.iso | en | |
dc.publisher | Saudi Med J | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | General & Internal Medicine | |
dc.title | Heat Shock Protein 60 Antibody - A New Marker For Subsequent Atrialfibrillation Development | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.relation.journal | Saudi Medical Journal | |
dc.contributor.department | Tıbbi Biyokimya | |
dc.identifier.volume | 28 | |
dc.identifier.issue | 6 | |
dc.identifier.startpage | 844 | |
dc.identifier.endpage | 847 | |
dc.description.index | WoS | |