dc.contributor.author | Utku, Burkay | |
dc.contributor.author | Donmez, Gurhan | |
dc.contributor.author | Erisgen, Gulriz | |
dc.contributor.author | Akin, Senay | |
dc.contributor.author | Demirel, Haydar Ali | |
dc.contributor.author | Korkusuz, Feza | |
dc.contributor.author | Doral, Mahmut Nedim | |
dc.date.accessioned | 2019-12-10T11:32:22Z | |
dc.date.available | 2019-12-10T11:32:22Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 1300-0144 | |
dc.identifier.uri | https://doi.org/10.3906/sag-1602-60 | |
dc.identifier.uri | http://hdl.handle.net/11655/16027 | |
dc.description.abstract | Background/aim: Platelet-rich plasma (PRP) application has gained widespread interest for musculoskeletal injuries. Nonsteroidal antiinflammatory drugs are frequently used in sports medicine before and/or after PRP application. Our study seeks to determine whether serum levels of platelet-derived growth factor-AB (PDGF-AB) and vascular endothelial growth factor (VEGF) levels of PRP would be affected by nonsteroidal antiinflammatory drugs. Materials and methods: Two different final concentrations of diclofenac (0.5 mu g mL (1) and 2.5 mu g mL (1)), meloxicam (0.8 mu g mL (1) and 2.0 mu g mL (1)), and acetylsalicylic acid (final concentration 450 mu m) were obtained in separate tubes with PRPs prepared from 20 healthy male volunteers. Medicine-free PRP was the control group. Growth factors were measured using ELISA. Results: PDGF-AB and VEGF serum levels did not change with diclofenac, meloxicam, or acetylsalicylic acid addition. PDGF-AB and VEGF serum levels correlated with each other. Conclusion: Diclofenac, meloxicam, and acetylsalicylic acid did not affect PDGF-AB and VEGF serum levels. | |
dc.language.iso | en | |
dc.publisher | Tubitak Scientific & Technical Research Council Turkey | |
dc.relation.isversionof | 10.3906/sag-1602-60 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | General & Internal Medicine | |
dc.title | Meloxicam And Diclofenac Do Not Change Vegf And Pdgf-Ab Serum Levels Of Platelet-Rich Plasma | |
dc.type | info:eu-repo/semantics/article | |
dc.relation.journal | Turkish Journal Of Medical Sciences | |
dc.contributor.department | Spor Hekimliği | |
dc.identifier.volume | 47 | |
dc.identifier.issue | 2 | |
dc.identifier.startpage | 570 | |
dc.identifier.endpage | 576 | |
dc.description.index | WoS | |
dc.description.index | Scopus | |