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Now showing items 171-180 of 187
Role of Endothelial Nitric Oxide Generation and Peroxynitrite Formation in Reperfusion Injury After Focal Cerebral Ischemia
(Lippincott Williams & Wilkins, 2000)
Background and Purpose-Reperfusion injury is one of the factors that unfavorably affects stroke outcome and shortens the window of opportunity for thrombolysis. Surges of nitric oxide (NO) and superoxide generation on ...
Reperfusion-Induced Oxidative/Nitrative Injury To Neurovascular Unit After Focal Cerebral Ischemia
(Lippincott Williams & Wilkins, 2004)
Background and Purpose-Use of thrombolysis in stroke is limited by a short therapeutic window because delayed reperfusion may cause brain hemorrhage and edema. Available evidence suggests a role for superoxide, NO, and ...
Reversible Cerebral Vasoconstriction Syndromes Analysis of 139 Cases
(Amer Medical Assoc, 2011)
Objectives: To compare the clinical, laboratory, and imaging features of patients with reversible cerebral vasoconstriction syndromes evaluated at 2 academic centers, compare subgroups, and investigate treatment effects. ...
The Distinct Genetic Pattern of ALS in Turkey and Novel Mutations
(Elsevier Science Inc, 2015)
The frequency of amyotrophic lateral sclerosis (ALS) mutations has been extensively investigated in several populations; however, a systematic analysis in Turkish cases has not been reported so far. In this study, we ...
Systemically Administered Brain-Targeted Nanoparticles Transport Peptides Across the Blood-Brain Barrier and Provide Neuroprotection
(Nature Publishing Group, 2015)
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. ...
Temporal Lobe Epilepsy is a Predisposing Factor for Sleep Apnea: A Questionnaire Study in Video-Eeg Monitoring Unit
(Academic Press Inc Elsevier Science, 2015)
Objective: The interaction between epilepsy and sleep is known. It has been shown that patients with epilepsy have more sleep problems than the general population. However, there is no recent study that compares the frequency ...
The Association of Cognitive Impairment with Gray Matter Atrophy and Cortical Lesion Load in Clinically Isolated Syndrome
(Elsevier Sci Ltd, 2016)
Background: Multiple sclerosis can impair cognition from the early stages and has been shown to be associated with gray matter damage in addition to white matter pathology. Objectives: To investigate the profile of cognitive ...
The Activation of Rage and Nf-Kb in Nerve Biopsies of Patients with Axonal and Vasculitic Neuropathy
(Aves, 2015)
Introduction: The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor expressed in tissues and cells, which plays a role in immunity. The activation of RAGE results in the translocation ...
Vegf Protects Brain Against Focal Ischemia Without Increasing Blood-Brain Permeability When Administered Intracerebroventricularly
(Sage Publications Inc, 2005)
Delayed administration of vascular endothelial growth factor (VEGF) promotes functional recovery after focal cerebral ischemia. However, early intravenous injection of VEGF increases blood-brain barrier (BBB) leakage, ...
Validity And Reliability Of The Turkish Version Of The Questionnaire For The Assessment Of Dysphagia In Multiple Sclerosis
(Aves, 2018)
Introduction: The aim of this study was to investigate the validity and reliability of the Turkish version of the Questionnaire for the Assessment of DYsphagia in MUltiple Sclerosis (DYMUS) that has been developed for ...