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Toplam kayıt 71, listelenen: 21-30
A Phase II, Multicenter, Single-Arm Study to Evaluate the Safety and Efficacy of Deferasirox after Hematopoietic Stem Cell Transplantation in Children with Beta-Thalassemia Major
(Elsevier Science Inc, 2018)
We conducted a prospective, phase II, multicenter, single-arm study to evaluate the efficacy and safety of deferasirox in patients age >2 to <18 years with beta-thalassemia major (TM) who underwent hematopoietic stem cell ...
The Mutational Spectrum Of Ptpn11 In Juvenile Myelomonocytic Leukemia And Noonan Syndrome/Myeloproliferative Disease
(Amer Soc Hematology, 2005)
Germ line PTPN11 mutations cause 50% of cases of Noonan syndrome (NS). Somatic mutations in PTPN11 occur in 35% of patients with de novo, nonsyndromic juvenile myelomonocytic leukemia (JIMML). Myeloproliferative disorders ...
The European Hematology Association Roadmap for European Hematology Research: A Consensus Document
(Ferrata Storti Foundation, 2016)
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs ...
Loss of Maternal Allele in a Child with Myelodysplastic Syndrome and Monosomy 7
(Wiley-Liss, 1999)
Monosomy 7 or partial deletion of the long arm of chromosome 7 is frequently described in children with myelodysplastic syndrome and acute myeloblastic leukemia, Parental origin of chromosome 7 in children with sporadic ...
Myeloprotective Effect Of Short-Course High-Dose Methylprednisolone Treatment Before Consolidation Therapy In Children With Acute Myeloblastic Leukemia
(Wiley, 2005)
In our previous studies, short-course high-dose methylprednisolone (HDMP) has been shown to shorten the chemotherapy-induced neutropenic period by stimulating the CD34(+) hematopoietic progenitor cells in children with ...
Natural History And Early Diagnosis Of Lad-1/Variant Syndrome
(Amer Soc Hematology, 2007)
The syndrome of leukocyte adhesion deficiency (LAD) combined with a severe Glanzmann-type bleeding disorder has been recognized as a separate disease entity. The variability in clinical and cell biological terms has remained ...
Life-Threatening Neurological Complications after Bone Marrow Transplantation in Children
(Nature Publishing Group, 2005)
Neurological complications may occur in BMT recipients (11-59%), frequently contributing to morbidity or mortality. They are the main causes of death in 10-15%. Life-threatening neurological complications were seen in 11 ...
Molecular Diagnosis Of Shwachman-Diamond Syndrome Presenting With Pancytopenia At An Early Age: The First Report From Turkey
(Springer India, 2013)
A three-month-old boy presented with growth failure, skeletal abnormalities, otitis media and pancytopenia. Exocrine pancreatic insufficiency was confirmed by low levels of fecal elastase. He was diagnosed as Shwachman-Diamond ...
The Glycocalyx and Trauma: A Review
(Lippincott Williams & Wilkins, 2016)
In the United States trauma is the leading cause of mortality among those under the age of 45, claiming approximately 192,000 lives each year. Significant personal disability, lost productivity, and long-term healthcare ...
Molecular And Clinical Spectrum Of Type I Plasminogen Deficiency: A Series Of 50 Patients
(Amer Soc Hematology, 2006)
Severe type I plasminogen (PLG) deficiency has been causally linked to a rare chronic inflammatory disease of the mucous membranes that may be life threatening. Here we report clinical manifestations, PLG plasma levels, ...