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The Impact Of Jak1/Jak2 Inhibitor Ruxolitinib On The Spleen Size And Symptom Burden In Myeloproliferative Diseases
(Akad Doktorlar Yayınevi, 2016)
Ruxolitinib as a JAK1 and JAK2 inhibitor drug has recently been approved for the treatment of patients with high-or intermediate-risk myelofibrosis with symptomatic splenomegaly. Clinical development of ruxolitinib has ...
The Impact Of Red Cell Distribution Width And Neutrophil/Lymphocyte Ratio On Long-Term Survival After Pulmonary Resection For Non-Small Cell Lung Cancer
(Akad Doktorlar Yayınevi, 2016)
Red cell distribution width (RDW) and Neutrophil/Lymphocyte Ratio (NLR) are widely available blood tests which can be used to reflect patients' inflammatory status. We investigated the effects of RDW and NLR levels on ...
The Prognostic Value Of High Pretreatment Plasma D-Dimer Levels In Non-Metastatic Breast Cancer Patients With Absence Of Venous Thromboembolism
(Akad Doktorlar Yayınevi, 2016)
Systemic activation of coagulation and fibrinolysis is frequently observed in cancer patients without thrombosis. Recent studies have showed the association between D-Dimer (DD) and metastatic spread and prognosis of cancer. ...
Utility Of "Over D1" Or D1 Nodal Dissections In Predicting Outcome Of Patients With Gastric Adenocarcinoma Treated With Postoperative Concurrent Chemoradiotherapy
(Akad Doktorlar Yayınevi, 2012)
We retrospectively evaluated the utility "over D1" or D1 dissections on outcome of gastric cancer patients with subsequent postoperative chemoradiotherapy. Sixty-five patients with gastric adenocarcinoma treated with ...
Transarterial Chemo And Radioembolization (Yttrium90) Of Hepatic Metastasis Of Neuroendocrine Tumors: Single Center Experience
(Akad Doktorlar Yayınevi, 2013)
The aim of this study was to present our single center experience with short (< 3 months) and intermediate-term (> 3 months) follow-up results of patients who underwent transarterial radioembolization with yttrium-90 ...
Use Of Second Generation Tyrosine Kinase Inhibitors For Second-Line Treatment Of Chronic Myeloid Leukemia After Imatinib Failure
(Akad Doktorlar Yayınevi, 2011)
Invention of imatinib was a great step for much more successful clinical management of chronic myeloid leukemia (CML). Now, two other tyrosine kinase inhibitors (TKIs) are available both for first-line and later treatments ...
Thyroid Medullary Carcinoma In A Patient With Hiv/Aids
(Akad Doktorlar Yayınevi, 2012)
According to the clinical trials HIV positivity does not increase the frequency of thyroid malignancies. We present a patient with HIV positivity and thyroid medullary carcinoma. To our knowledge this is the second case ...
The Impact Of Iron Overload On Transplant-Related Complications And Prognosis Of Acute Leukemias
(Akad Doktorlar Yayınevi, 2016)
The impacts of serum iron parameters and/or radiological evidence of systemic iron overload on the prognosis of hematopoietic stem cell transplantation (HSCT) in acute leukemia are controversial. Unfortunately, some of the ...
The Effects of Noise on Oxidative and Antioxidative Balance in Human Erythrocytes
(Akad Doktorlar Yayınevi, 2011)
Reactive oxygen and nitrogen species have been implicated in the pathogenesis of noise-induced hearing loss. In this case-control study, we investigated the oxidative and antioxidative status of erythrocytes from workers ...
Serum Human Epididymis Protein 4 (HE4) As a Diagnostic and Follow-Up Biomarker in Patients with Non-Small Cell Lung Cancer
(Akad Doktorlar Yayınevi, 2017)
Early detection of non-small cell lung cancer (NSCLC) cases is crucial since nearly one third of them are unresectable during diagnosis and also the recurrence rates are high following treatment. Thus, in this study we ...