dc.contributor.author | Turgut, M | |
dc.contributor.author | Sunbul, M | |
dc.contributor.author | Bayirli, D | |
dc.contributor.author | Bilge, A | |
dc.contributor.author | Leblebicioglu, H | |
dc.contributor.author | Haznedaroglu, I | |
dc.date.accessioned | 2019-12-10T11:21:01Z | |
dc.date.available | 2019-12-10T11:21:01Z | |
dc.date.issued | 2002 | |
dc.identifier.issn | 0300-0605 | |
dc.identifier.uri | https://doi.org/10.1177/147323000203000511 | |
dc.identifier.uri | http://hdl.handle.net/11655/15418 | |
dc.description.abstract | Leptospirosis can present with a wide clinical spectrum, and haematological manifestations are often apparent. We retrospectively analysed platelet counts in 49 patients with leptospirosis. Forty-three patients (87.8%) had thrombocytopenia. Mean baseline platelet counts rose from 69 x 10(9)/1 to 151 x 10(9)/1 following treatment. Haemorrhagic episodes were observed in 11 patients. Platelet nadir was 29 x 10(9)/1 in the group experiencing bleeding and 64 x 10(9)/1 in the remainder. Six patients died due to bleeding and one due to sepsis. Thirty-six patients (73.5%) had acute renal failure; their mean platelet count was 46 x 10(9)/1. Liver enzyme levels were elevated in all patients. Thrombocyte count, liver enzyme levels and bilirubin levels were significantly correlated. Forty-three (87.8%) patients showed signs of sepsis; mean thrombocyte count was 46 x 10(9)/1 in these patients, and 133 x 10(9)/1 in those without sepsis. Multiple organ involvement and fulminant disease is usually associated with renal failure and/or thrombocytopenia in leptospirosis. | |
dc.language.iso | en | |
dc.publisher | Cambridge Med Publ | |
dc.relation.isversionof | 10.1177/147323000203000511 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Research & Experimental Medicine | |
dc.subject | Pharmacology & Pharmacy | |
dc.title | Thrombocytopenia Complicating The Clinical Course Of Leptospiral Infection | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.relation.journal | Journal Of International Medical Research | |
dc.contributor.department | İç Hastalıkları | |
dc.identifier.volume | 30 | |
dc.identifier.issue | 5 | |
dc.identifier.startpage | 535 | |
dc.identifier.endpage | 540 | |
dc.description.index | WoS | |
dc.description.index | Scopus | |