dc.contributor.author | Hasanov, Elshad | |
dc.contributor.author | Hasanov, Merve | |
dc.contributor.author | Kuria, Issa M. | |
dc.contributor.author | Hasanov, Rovshan | |
dc.contributor.author | Rzazade, Reshad | |
dc.contributor.author | Jonasch, Eric | |
dc.contributor.author | Altundag, Kadri | |
dc.date.accessioned | 2019-12-10T11:12:06Z | |
dc.date.available | 2019-12-10T11:12:06Z | |
dc.date.issued | 2017 | |
dc.identifier.issn | 0025-7974 | |
dc.identifier.uri | https://doi.org/10.1097/MD.0000000000006785 | |
dc.identifier.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571986/ | |
dc.identifier.uri | http://hdl.handle.net/11655/15010 | |
dc.description.abstract | Rationale: Tamoxifen has been used in women with hormone receptor-positive breast cancer and has been shown to successfully reduce both recurrence and mortality. On the contrary, long-term use of tamoxifen has hormone-related urogenital side effects which decrease the quality of life of the patients. Patient concerns: In this case report, we present a breast cancer patient receiving tamoxifen who developed urinary incontinence; we discuss the effects of tamoxifen on urinary incontinence, which decreases quality of life of the patients who were evaluated in our clinic. Diagnoses: Breast cancer, urinary incontinence. Interventions: Temporarily discontinuing tamoxifen. Outcomes: Urinary incontinence resolved. Lessons: Based on the case we reported and literature, estrogen can cause a dose-dependent increase in incontinence, but more preclinical and clinical studies of both estrogen and SERMs are needed to support this notion; given the fact that some small-scale clinical studies have not proven a direct relationship between tamoxifen and urinary incontinence. We suggest that clinicians faced with the issue should temporarily stop usage of the drug once the complaint of urinary incontinence arises. | |
dc.relation.isversionof | 10.1097/MD.0000000000006785 | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Effects Of Tamoxifen On Urinary Incontinence | |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion | |
dc.relation.journal | Medicine | |
dc.contributor.department | İç Hastalıkları | |
dc.identifier.volume | 96 | |
dc.identifier.issue | 34 | |
dc.description.index | PubMed | |
dc.description.index | WoS | |
dc.description.index | Scopus | |