Factor V Q 506 Mutation In Children With Thrombosis

Abstract

The factor V Leiden mutation in 12-children with thrombosis and in 20 controls was investigated, Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found, Central nervous system thromboses were increased in children with the factor V mutation, associated with protein S deficiency. (C) 1996 Wiley-Liss, Inc.