Eular/Pres Endorsed Consensus Criteria For The Classification Of Childhood Vasculitides
Tarih
2006Yazar
Ozen, Seza
Ruperto, N
Dillon, MJ
Bagga, A
Barron, K
Davin, JC
Kawasaki, T
Lindsley, C
Petty, RE
Prieur, AM
Ravelli, A
Woo, P
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Background: There has been a lack of appropriate classification criteria for vasculitis in children. Objective: To develop a widely accepted general classification for the vasculitides observed in children and specific and realistic classification criteria for common childhood vasculitides (Henoch-Schonlein purpura (HSP), Kawasaki disease (KD), childhood polyarteritis nodosa ( PAN), Wegener's granulomatosis (WG), and Takayasu arteritis (TA)). Methods: The project was divided into two phases: (1) the Delphi technique was used to gather opinions from a wide spectrum of paediatric rheumatologists and nephrologists; (2) a consensus conference using nominal group technique was held. Ten international experts, all paediatricians, met for the consensus conference. Agreement of at least 80% of the participants was defined as consensus. Results: Consensus was reached to base the general working classification for childhood vasculitides on vessel size. The small vessel disease was further subcategorised "intogranulomatous'' and `"nongranulomatous.'' Final criteria were developed to classify a child as HSP, KD, childhood PAN, WG, or TA, with changes introduced based on paediatric experience. Mandatory criteria were suggested for all diseases except WG. Conclusions: It is hoped that the suggested criteria will be widely accepted around the world because of the reliable techniques used and the international and multispecialist composition of the expert group involved.