Show simple item record

dc.contributor.authorZhao, Yongdong
dc.contributor.authorWu, Eveline Y.
dc.contributor.authorOliver, Melissa S.
dc.contributor.authorCooper, Ashley M.
dc.contributor.authorBasiaga, Matthew L.
dc.contributor.authorVora, Sheetal S.
dc.contributor.authorLee, Tzielan C.
dc.contributor.authorFox, Emily
dc.contributor.authorAmarilyo, Gil
dc.contributor.authorStern, Sara M.
dc.contributor.authorDvergsten, Jeffrey A.
dc.contributor.authorHaines, Kathleen A.
dc.contributor.authorRouster-Stevens, Kelly A.
dc.contributor.authorOnel, Karen B.
dc.contributor.authorCherian, Julie
dc.contributor.authorHausmann, Jonathan S.
dc.contributor.authorMiettunen, Paivi
dc.contributor.authorCellucci, Tania
dc.contributor.authorNuruzzaman, Farzana
dc.contributor.authorTaneja, Angela
dc.contributor.authorBarron, Karyl S.
dc.contributor.authorHollander, Matthew C.
dc.contributor.authorLapidus, Sivia K.
dc.contributor.authorLi, Suzanne C.
dc.contributor.authorOzen, Seza
dc.contributor.authorGirschick, Hermann
dc.contributor.authorLaxer, Ronald M.
dc.contributor.authorDedeoglu, Fatma
dc.contributor.authorHedrich, Christian M.
dc.contributor.authorFerguson, Polly J.
dc.date.accessioned2019-12-10T10:35:27Z
dc.date.available2019-12-10T10:35:27Z
dc.date.issued2018
dc.identifier.issn2151-464X
dc.identifier.urihttps://doi.org/10.1002/acr.23462
dc.identifier.urihttp://hdl.handle.net/11655/13879
dc.description.abstractObjective. To develop standardized treatment regimens for chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO), to enable comparative effectiveness treatment studies. Methods. Virtual and face-to-face discussions and meetings were held within the CNO/CRMO subgroup of the Childhood Arthritis and Rheumatology Research Alliance (CARRA). A literature search was conducted, and CARRA membership was surveyed to evaluate available treatment data and identify current treatment practices. Nominal group technique was used to achieve consensus on treatment plans for CNO refractory to nonsteroidal antiinflanunatory drug (NSAID) monotherapy and/or with active spinal lesions. Results. Three consensus treatment plans (CTPs) were developed for the first 12 months of therapy for CNO patients refractory to NSAID monotherapy and/or with active spinal lesions. The 3 CTPs are methotrexate or sulfasalazine, tumor necrosis factor inhibitors with optional methotrexate, and bisphosphonates. Short courses of glucocorticoids and continuation of NSAIDs are permitted for all regimens. Consensus was achieved on these CTPs among CARRA members. Consensus was also reached on subject eligibility criteria, initial evaluations that should be conducted prior to the initiation of CTPs, and data items to collect to assess treatment response. Conclusion. Three consensus treatment plans were developed for pediatric patients with CNO refractory to NSAIDs and/or with active spinal lesions. Use of these CTPs will provide additional information on efficacy and will generate meaningful data for comparative effectiveness research in CNO.
dc.language.isoen
dc.publisherWiley
dc.relation.isversionof10.1002/acr.23462
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectRheumatology
dc.titleConsensus Treatment Plans For Chronic Nonbacterial Osteomyelitis Refractory To Nonsteroidal Antiinflammatory Drugs And/Or With Active Spinal Lesions
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalArthritis Care & Research
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları
dc.identifier.volume70
dc.identifier.issue8
dc.identifier.startpage1228
dc.identifier.endpage1237
dc.description.indexWoS


Files in this item

This item appears in the following Collection(s)

Show simple item record