Browsing Sağlık Bilimleri Enstitüsü by Title
Now showing items 64-83 of 94
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Migren Tedavisinde Kullanılmak Üzere Geliştirilen Hibrit Nanopartiküllerin İn Vitro ve İn Vivo Etkinliklerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Kaya MZ. Evaluation of In Vitro and In Vivo Activities of Hybrid Nanoparticles Developed for the Treatment of Migraine, PhD Thesis, Pharmaceutical Technology Program, Graduate School of Health Sciences, Hacettepe University, ... -
Mikrodizin kaynaklı genotip bilgisi kullanılarak kopya sayısı değişikliklerinde mozaiklik oranının saptanması
(Sağlık Bilimleri Enstitüsü, 2023)Acun, H. M., Determination of Mosaicism Ratio in Copy Number Variations Using Microarray Based Genotype Information, Hacettepe University Graduate School of Health Sciences Department of Bioinformatics Master’s Thesis, ... -
Mikrorna-21 Baskılanmış Meme Kanseri Kök Hücrelerinin İnsan Kemik İliğinden İzole Edilen Telositler ve Telosit Kaynaklı Mitokondriler ile Ko-Kültürü
(Sağlık Bilimleri Enstitüsü, 2023)The aim of this thesis study was to investigate the contribution of telocytes and telocyte-derived mitochondria, which have also been identified in breast tumours, to the tumour development of breast cancer stem cells via ... -
Myastenia Gravis’li Bireylerde Kognitif İşlevin Basit ve Kompleks Reaksiyon Zamanı Yöntemi ile Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Myasthenia Gravis (MG) is an autoimmune disease caused by antibodies against mainly postsynaptic proteins that play an important role in the function of the neuromuscular junction. Function disruption of the junction leads ... -
Non-Segmental Vitiligo ile HLA Genotipi Ve Oksidatif Stres Arasındaki İlişki
(Sağlık Bilimleri Enstitüsü, 2019)Vitiligo is an autoimmune skin diseases characterized by acquired loss of functional melanocytes. Although the pathogenesis of vitiligo remains poorly understood, oxidative stress and autoimmune disregulations are considered ... -
Nörofibromatozis Tip 1(Nf1) Kaynaklı Mezenkimal Stromal Hücrelerin Detaylı Karakterizasyonu
(Sağlık Bilimleri Enstitüsü, 2022-10-07)Neurofibromatosis type 1 (NF1) is an inherited autosomal dominant disease characterized by mutation in the neurofibromin (NF1) tumor suppressor gene. The lack of neurofibromin, the gene product, causes defects in the nervous ... -
Oksidatif Stres Altında Mezenkimal Kök Hücrelerde Src-YAP Aktivitesi ve Apoptoz ile İlişkisi
(Sağlık Bilimleri Enstitüsü, 2024)One of the reasons for the post-transplantation loss of mesenchymal stem cells (MSCs), which are used in the treatment of many diseases with their immunomodulatory and regenerative properties, is oxidative stress-induced ... -
Optimization and Risk Assessment of RAB27A-/- Gene Therapy Alternatives Using Current Molecular Techniques and Technologies
(Sağlık Bilimleri Enstitüsü, 2024-02-09)EROL DUYAR, Ö.D. Optimization and Risk Assessment of RAB27A-/- Gene Therapy Alternatives using Current Molecular Techniques and Technologies. Hacettepe University Graduate School of Health Sciences Stem Cell Doctor of ... -
Otizm Tanılı Çocuklarda Etiyolojik Faktörlerin İncelenmesi: Bir Vaka Kontrol Araştırması
(Sağlık Bilimleri Enstitüsü, 2022)The frequency of autism, a neurodevelopmental disorder, has been increasing in recent years. One out of every 59 children is diagnosed with autism, and nearly three-quarters of those diagnosed need lifelong educational and ... -
Paramedik Programı Öğrencilerinin Triyaj Yönetiminde Görsel Olarak Geliştirilmiş Zihinsel Simülasyonun Etkililiği
(Sağlık Bilimleri Enstitüsü, 2020)Demir, S., The Effectiveness of Visually Enhanced Mental Simulation in Triage Management of Paramedic Program Students. Hacettepe University Institute of Health Sciences Simulation Program in Health Sciences Master's Thesis, ... -
Podosit Hasar Modelinde İndüklenmiş Mezenkimal Kök Hücrelerinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2023-02-08)Sahan, OB., The Effect of İnduced Mesenchymal Stem Cells On Podocyte Injury Model, Hacettepe University Graduate School of Health Sciences Department of Stem Cell Sciences Doctor of Philosophy Thesis, Ankara,2023. Self-renewal, ... -
Polikistik Over Sendromlu Ergenlerde Kas Kuvvetinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2024)Polycystic ovary syndrome (PCOS) is an endocrinological disease, the foundations of which are are laid in adolescence, is most common in women of reproductive age and progresses with androgen elevation and chronic anovulation. ... -
Postpartum Dönemde Vücut Algısının Cinsel Yaşam Kalitesine Etkisi
(Sağlık Bilimleri Enstitüsü, 2024)This research was conducted as adescriptive and cross-sectional study to examine the effect of women’s postpartum body image on their quality of sexual life. The research as conducted at Kastamonu Training and Research ... -
Preeklampsi Hastalığının Erken Tanısına Yönelik Hedeflenmiş Metabolomik Çalışmalar İçin Gc-Ms Yöntemi Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2022-02-25)Kus Kale., Development of GC-MS Method for Targeted Metabolomic Studies for Early Diagnosis of Preeclampsia Disease. Hacettepe University Graduate School Health Sciences, Analytical Chemistry Program, Master's Thesis, ... -
Prematüre bebeklerde prenatal Doppler Ultrasonografi bulguları ile postnatal serebral Near-Infrared Spektroskopi (NIRS) ölçümlerinin uyumluluğunun araştırılması
(Sağlık Bilimleri Enstitüsü, 2023-06-19)Perinatal and neonatal surveillance of intrauterine growth restriction (IUGR) has gained importance due to its negative impacts on cerebral oxygenation. In this thesis study, it was aimed to compare fetal cerebral and ... -
Prokainamidin Farmasötik Preparattan ve Plazmadan Yeşil Hplc vle Analizi
(Sağlık Bilimleri Enstitüsü, 2022)In drug analysis, using non-hazardous solvents instead of these solvents harmful to the human and environment is a greening strategy to protect analyst and environmental health and minimize produced toxic waste budged. ... -
Sağlıklı İnsan Uyarılmış Pluripotent Kök Hücrelerinden (uPKH’lerden) NGN2, LHX3 ve ISL1 Üçlü Kasedi Kullanarak Motor Nöron Eldesi
(Sağlık Bilimleri Enstitüsü, 2023)Neurodegenerative diseases are progressive and fatal diseases that reduce the standard of living of individuals and cause significant functional losses. Amyotropic lateral sclerosis (ALS) is a disease caused by motor neurone ... -
Sağlıklı İnsan Uyarılmış Pluripotent Kök Hücrelerinden Kortikal Nöron Elde Edilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Induced pluripotent stem cells (iPSC) are a unique resource for personalized treatment, disease modeling and drug trials. Target tissue and organ formation can be achieved with various transcription factors or small molecules ... -
Smoking Induces Coordinated Dna Methylation and Gene Expression Changes in Adipose Tissue with Consequences for Metabolic Health
(Springer Nature, 2018)Background: Tobacco smoking is a risk factor for multiple diseases, including cardiovascular disease and diabetes. Many smoking-associated signals have been detected in the blood methylome, but the extent to which ... -
Spontaneous Thrombosis of Significant Aneurysm Recanalization in the Long Term Follow-Up of Coiled Aneurysms - Observation in Two Cases
(Edizioni Centauro, 2005)Endovascular treatment of cerebral aneurysms with detachable coils has now been proved to be a superior alternative to open microsurgery in terms of survival free of disability at one year according to the recently published ...