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Fare Ligaman Perforasyon SAK modelinde Squalene Adenozin Nanoparçaların Beyin Kan Akımı ve Nörolojik Skorlara Etkisi
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2019)
The aim of this study is to investigate the cerebral blood flow (CBF) changes in the first 24 hours following SAH, the effect of intravenous squalene-adenosine on CBF, functional outcome of mice and cerabral histologic ...
12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke
(Lippincott Williams & Wilkins, 2017)
Background and Purpose For stroke prevention, patients with atrial fibrillation typically receive oral anticoagulation. The commonly used anticoagulant warfarin increases the risk of hemorrhagic transformation (HT) when a ...
Mutation Analysis Of The Pink1 Gene In 391 Patients With Parkinson Disease
(Amer Medical Assoc, 2008)
Objectives: To determine the frequency, distribution, and clinical features of Parkinson disease (PD) with PINK1 mutations. Design: Retrospective clinical and genetic review. Setting: University hospital. Patients: We ...
Mutations in A Human Robo Gene Disrupt Hindbrain Axon Pathway Crossing and Morphogenesis
(Amer Assoc Advancement Science, 2004)
The mechanisms controlling axon guidance are of fundamental importance in understanding brain development. Growing corticospinal and somatosensory axons cross the midline in the medulla to reach their targets and thus form ...
Default Mode Network Connectivity Is Linked to Cognitive Functioning and Csf A Beta(1-42) Levels In Alzheimer'S Disease
(Elsevier Ireland Ltd, 2016)
Background: Changes in the default mode network (DMN) activity are early features of Alzheimer's disease (AD) and may be linked to AD-specific A beta pathology. Methods: Cognitive profiles; DMN connectivity alterations; ...
Glikojenin İskemik İnme ve Retinal İskemi Üzerine Olan Etkilerinin Nörogliovasküler Seviyede İncelenmesi
(Nörolojik Bilimler ve Psikiyatri Enstitüsü, 2020-01-16)
Ischemic stroke results in sudden blood flow cessation thus leads to sudden onset unmet energy requirements. Although the clotted artery is recanalized and blood flow is restored back, brain perfusion may not be sustained ...
Neuro-Ophthalmologic Findings In Humans With Quadrupedal Locomotion
(Informa Healthcare, 2012)
Purpose: To report the neuro-ophthalmologic findings in four patients from the same family with cerebellar ataxia, mental retardation, and dysequilibrium syndrome (CAMRQ) 2 associated with quadrupedal locomotion. Method: ...
Nuclear Expansion And Pore Opening Are Instant Signs Of Neuronal Hypoxia And Can Identify Poorly Fixed Brains
(Nature Publishing Group, 2018)
The initial phase of neuronal death is not well characterized. Here, we show that expansion of the nuclear membrane without losing its integrity along with peripheralization of chromatin are immediate signs of neuronal ...
Refractory Lesional Parietal Lobe Epilepsy: Clinical, Electroencephalographic and Neurodiagnostic Findings
(Aves, 2016)
Introduction: Specialized centers, in the management and surgical treatment of medically refractory epilepsy, emphasize the importance of differentiating the varieties of localization related epilepsies. There has been ...
Plasma Glycine and Serine Levels in Schizophrenia Compared to Normal Controls and Major Depression: Relation to Negative Symptoms
(Oxford Univ Press, 2004)
Previous Studies have suggested decreased N-methyl-D-aspartate (NMDA)-type glutamate receptor function may contribute to increased negative symptoms in patients with schizophrenia. Consistent with this hypothesis, glycine, ...