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Toplam kayıt 79, listelenen: 61-70
The Effect of Inducıble Costımulatory Lıgand (Icos-Lg) Expressıng Myeloıd Leukemıa Cells on Helper T Lymphocyte Actıvatıon and Exhaustıon
(Kanser Enstitüsü, 2015)
T cell exhaustion is characterized by progressive loss of cytokine production, decreased proliferation and resistance to reactivation especially upon continuous antigen stimulation. Despite being potent stimulators of ...
Expression of Toll Like Receptors in Lung Cancer and Investigating Their Effect on Apoptosis
(Kanser Enstitüsü, 2014)
Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ...
Meme Kanseri Hücrelerinde Pı-103 Inhibitörünün Aktive Reseptör Tirozin Kinaz Ekspresyonuna Etkisinin Incelenmesi
(Kanser Enstitüsü, 2014)
Oncogenic activation of PI3K/Akt/mTOR signaling pathway is frequently seen in breast cancer. Inhibition of signaling pathway by PI3K inhibitors, tyrosine kinase inhibitors and/or monoclonal antibodies causes increase in ...
Meme Kanseri Hücrelerinde Kostimülatör B7 Ailesi Ligandlarının Ekspresyonu ve Yardımcı T Hücre Yanıtları Üzerine Etkisi
(Kanser Enstitüsü, 2013)
B7 ligands are the most critical costimulatory molecules that regulate T cell responses. Although these molecules are mainly expressed on professional antigen presenting cells, they may also be expressed on tumor cells. ...
Meme Kanseri Modelinde Myeloid Kökenli Hücrelerin Immün Kompartmanlardaki Dağılımının Anti-Tümör Yanıtlara Yansıması
(Kanser Enstitüsü, 2013)
Myeloid cells of peripheral blood, bone
marrow and spleens from NMU induced mammary tumor bearing Sprague-Dawley
rats were examined in this study. Myeloid derived suppressor cells (MDSCs) in
tumor bearing rats are defined ...
Kolon Kanserli Hastalarda Interlökin 21 ve Interlökin32 Gen Ekspesyon Düzeyleri ve Metastaz Ilişkisi
(Kanser Enstitüsü, 2014)
Tumor microenvironment contains tumor cells, immune cells, stroma and stroma associated immune cells. This microenvironment of the immune system cells release chemokines and cytokines which play an important role in the ...
Reproductive Cancer Risk Factors Among Relatives of Cancer Patients Seeking Treatment in Hacettepe University Oncology Hospital
(Kanser Enstitüsü, 2014)
This study is an attempt to measure the frequency of specific gynecological cancer risk factors in female relatives of cancer patients. A cancer risk assessment questionnaire had been designed in the Department of Preventive ...
Mikozis Fungoides Mikroçevresinde Bulunan Dermal Fibroblastların Anti-Tümör İmmün Yanıta Etkisi
(Sağlık Bilimleri Enstitüsü, 2017-12)
Mycosis fungoides (MF) is the most common primary cutaneous T-cell lymphoma. The interaction of the neoplastic lymphocytes with their microenvironment is of crucial importance in disease progression. Cancer associated ...
Meme Kanseri Hücreleri Tarafından Üretilen Fibronektinin Miyeloid Hücre Karakteri Üzerine Etkisi
(Kanser Enstitüsü, 2019)
Basal-like breast cancer (BLBC) possess high capacity to regulate inflammation and identified with
high-level myeloid cell infiltration. Extracellular matrix components produced by tumor cells, e.g. fibronectin (FN), can ...
Efficacy of Sorafenib In Advanced Differentiated and Medullary Thyroid Cancer: Experience In A Turkish Population
(Dovepress, 2014)
Purpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus ...