Başlık için Kanser Enstitüsü listeleme
Toplam kayıt 110, listelenen: 82-101
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Racial Disparity in Tumor Microenvironment and Outcomes in Residual Breast Cancer after Neoadjuvant Chemotherapy
(Kanser Enstitüsü, 2023-06-12)Black patients with residual estrogen receptor-positive (ER+) breast cancer after neoadjuvant chemotherapy (NAC) have inferior survival compared to white women resulting racial disparity in breast cancer survival. Differences ... -
Reproductive Cancer Risk Factors Among Relatives of Cancer Patients Seeking Treatment in Hacettepe University Oncology Hospital
(Kanser Enstitüsü, 2014)This study is an attempt to measure the frequency of specific gynecological cancer risk factors in female relatives of cancer patients. A cancer risk assessment questionnaire had been designed in the Department of Preventive ... -
Selection and Charaterization of İmmune-Resistant Acute Myeloid Leukemia Cells
(Kanser Enstitüsü, 2024)Resistance to immunity is associated with the selection of cancer cells with superior capacities to survive inflammatory reactions. In the case of AML, immune reactions induce dynamic changes at genetic and epigenetic ... -
Serum 25-Hydroxy Vitamin D Status Is Not Related To Osteopenia/Osteoporosis Risk in Colorectal Cancer Survivors
(Asian Pacific Organization Cancer Prevention, 2014)Background: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated ... -
Single Institution Experience on Cancer Among Adolescents 15-19 Years of Age
(Turkish J Pediatrics, 2017)Adolescent cancers differ from other age groups in terms of cancer types, treatment and outcome. We aimed to present our institutional data on survival of certain types of cancer in adolescents. Hospital files were ... -
Smoking Habits of Relatives of Patients with Cancer: Cancer Diagnosis in the Family is an Important Teachable Moment for Smoking Cessation
(Asian Pacific Organization Cancer Prevention, 2013)Background: In this study we aimed to determine the rate and habitual patterns of smoking, intentions of cessation, dependence levels and sociodemographic characteristics of relatives of patients with a diagnosis of cancer. ... -
Smooth Muscle Cells Isolated from Thoracic Aortic Aneurysms Exhibit Increased Genomic Damage, but Similar Tendency for Apoptosis
(Mary Ann Liebert, Inc, 2012)Aortic aneurysms (AA) are characterized by structural deterioration leading to progressive dilation. During the development of AA, two key structural changes are pronounced, one being degradation of extracellular matrix ... -
Stereotactic Re-Irradiation For Recurrent Or Second Primary Head-And-Neck Cancer
(The Official Journal of Turkish Society for Radiation Oncology, 2018)Local recurrence after definitive radiotherapy for advanced head-and-neck cancer is observed in 30%– 60% of the patients. Surgical resection is possible in only about 25% of the cases. Re-irradiation for local recurrence ... -
Stereotaktik Radyocerrahi ve Stereotaktik Beden Radyoterapisi Uygulamalarında Manyetik Rezonans Görüntüleme Tabanlı Tedavi Planlama Sisteminin Kullanılabilirliği
(Kanser Enstitüsü, 2021-02-05)In this study, feasibility of Magnetic Resonance Imaging (MRI) based treatment planning system instead of computed tomography (CT) in SRC and SBRT was evaluated. Three different scenarios were created for density and ... -
Successful Treatment of Intracaval and Atrial Extension of Wilms' Tumour by Chemotherapy
(British Med Journal Publ Group, 1996)A patient presenting with advanced Wilms' tumour was diagnosed as having inferior vena cava involvement with tumour thrombus extending up to the right atrium, and was treated with preoperative chemotherapy (vincristine, ... -
Systemıc Vh4-34-Encoded Antıbody Responses Agaınst Commensal Bacterıa in Patıents Wıth Systemıc Lupus Erythematosus
(Kanser Enstitüsü, 2023-09)The germline immunoglobulin variable heavy chain 4–34 encoding B lymphocytes (known as VH4–34 or 9G4 B cells) are endowed with inherent self-reactivity due to the presence of a germline AVY motif in their framework region ... -
Tamoxifen-Induced Tissue Factor Pathway Inhibitor Reduction: A Clue for an Acquired Thrombophilic State?
(Oxford Univ Press, 2004)Background: Current understanding of hemostatic systems enables us to better explore the enigmatic pathobiology of tamoxifen (TAM)-induced thrombotic diathesis. We have therefore aimed to assess the hemostatic changes in ... -
Targeted Therapies in Gastric Cancer and Future Perspectives
(Baishideng Publishing Group Inc, 2016)Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research ... -
The Association Between Body Mass Index and Immunohistochemical Subtypes in Breast Cancer
(Elsevier, 2017)Background:Body mass index (BMI) is defined as a poor prognostic factor in patients with breast cancer(BC). However, there are controversial results regarding the various effects of BMI on BC, hence the exactpathophysiology ... -
The Effect of Acute Myeloid Leukemia Cells Expressing PD-L2 Co-Stimulatory Molecule on Helper T Cell Activation
(Sağlık Bilimleri Enstitüsü, 2017-07-25)The binding of PD-1 to its ligands (PD-L1 and PD-L2) inhibits and/or regulates T cell responses. Myeloid leukemia cells can express both co-activatory and co-inhibitory molecules simultaneously. The function of PD-L1 in ... -
The Effect of Inducıble Costımulatory Lıgand (Icos-Lg) Expressıng Myeloıd Leukemıa Cells on Helper T Lymphocyte Actıvatıon and Exhaustıon
(Kanser Enstitüsü, 2015)T cell exhaustion is characterized by progressive loss of cytokine production, decreased proliferation and resistance to reactivation especially upon continuous antigen stimulation. Despite being potent stimulators of ... -
The Effects of Tumor Mıcroenvironment on T Cell Responses in a Rat Chemical Mammary Carcinoma Model
(Kanser Enstitüsü, 2013)The studies that have investigated the nature of the cells and molecules responsible for the functional insufficiency of the tumor infiltrating T cells usually on several components; however, the contribution of stromal ... -
The Relationship of Agmatine Deficiency with the Lung Cancer
(Akad Doktorlar Yayınevi, 2016)The polyamines are essential for rapidly growing cells. Polyamines is synthesized by two reactions which begin from arginine. The aim of this study is to examine the serum levels of the enzymes located in the putrescine ... -
The Role of Regnase-1 Protein in Sculpting of Tumor Microenvironment
(Kanser Enstitüsü, 2021)The tumor microenvironment (TME) contains cancer-associated fibroblasts (CAFs) and their tumor-supportive role helps to build an environment in favor of cancer cell progression. Recent researches have revealed that targeting ... -
Tip-1 Yardımcı T (Th1) Hücrelerin Radyasyon Stresi Altında Fonksiyonel ve Fenotipik Değişimlerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022-07-18)It's critical to understand changes in the functional and phenotypic status of T cells, which play a key role in the anti-tumor response due to the immunosuppressive environment in the tumor microenvironment. In chronic ...