Başlık için Kanser Enstitüsü listeleme
Toplam kayıt 111, listelenen: 29-48
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Expression and Functional Analysis of Ccrl2 Atypical Chemokine Receptor Variants on Breast Cancer Cells
(Kanser Enstitüsü, 2014)The complex network of chemokines and chemokine receptors is regulated by atypical (decoy) chemokine receptors. Atypical chemokine receptors play role in the termination of inflammatory responses and CCRL2 is the newest ... -
Expression of Toll Like Receptors in Lung Cancer and Investigating Their Effect on Apoptosis
(Kanser Enstitüsü, 2014)Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ... -
Farklı Aktivasyon Basamaklarına İlerletilen Yardımcı T Hücrelerinde Adezyon ve Migrasyon Mekanizmalarının İncelenmesi
(Kanser Enstitüsü, 2020)When different analog T lymphocyte profiles are examined in cancer and chronic infections, these cells can be divided into two subgroups with functional and dysfunctiononal characterization. Naive T lymphocytes which are ... -
Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-like Receptors (TLR) on Regulation of the Central B cell Tolerance Checkpoint
(Sağlık Bilimleri Enstitüsü, 2022-09)Çakan, E., Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-Like Receptors (TLR) on Regulation of the Central B Cell Tolerance Checkpoint, Hacettepe University Graduate School Health Sciences Program ... -
Gastrointestinal Sistem Kanserli Hastalarda Mide Doluluğunun Radyoterapiye Etkisi
(Kanser Enstitüsü, 2017)In the treatment of gastrointestinal system (GIS) cancers, radiotherapy (RT) is frequently applied as three dimensional conformal RT (3BKRT) or intensity adjusted RT (YART). GIS tumors are very sensitive to environmental ... -
Genişletilmiş Bilgisayarlı Tomografi Skalası Ve Metal Artefakt Azalımı Yöntemlerinin İmplantlı Hastalarda Doz Dağılımına Etkisinin Bireyselleştirilmiş Fantomlar Kullanılarak Analiz Edilmesi
(Kanser Enstitüsü, 2019-09)Analysis of The Effects of Extended Computed Tomography Scale and Metal Artefact Reduction Methods on Dose Distribution of Patient with Implant by Using Individualized Fantoms. Hacettepe University Graduated School of ... -
Good Outcomes Of Patients With Stage Ib Endometrial Cancer With Surgery Alone
(Asian Pacific Organization Cancer Prevention, 2014)Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/radiotherapy ... -
Hacettepe Üniversitesi Onkoloji Hastanesinde Yatmakta Olan Hastalara Bakım Verenlerin Sosyodemografik Özelliklerinin ve Yaşam Kalitelerinin, Hastaların Yaşam Kalitesi Üzerine Etkisi
(Kanser Enstitüsü, 2022)Güner Üliç. P., The Effects of Sociodemographic Characteristics and Quality Of Life of Caregivers on Quality of Life of Inpatient Cancer Patients in Hacettepe University Oncology Hospital, Hacettepe University Graduate ... -
Helikal Tomoterapi ile Prostat Işınlamalarında Kritik Organ Dozlarının Cihaz İçi Parametrelere göre Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)The treatment planning of Tomotherapy depends on three device parameters, i.e. field width (FW), pitch (P) and modulation factor (MF). Various treatment plans can be generated with different combinations of these parameters. ... -
HER2 EKSPRESYONU OLAN MEME KANSERİ HÜCRELERİNDE ÖKARYOTİK ELONGASYON FAKTÖR-2 KİNAZ (eEF2K) AKTİVASYONUNUN ROLÜ
(Kanser Enstitüsü, 2021-06-22)Continuous activation of HER2 leads to the deregulation of various biological responses such as cell proliferation, survival, and migration, and tumor growth. eEF2K is a protein kinase involved in the regulation of protein ... -
Higher Ki67 Expression Is Associates With Unfavorable Prognostic Factors and Shorter Survival in Breast Cancer
(Asian Pacific Organization Cancer Prevention, 2014)Background: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, ... -
Hipoksinin Anti-Tümor İmmün Yanıt Üzerine Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Inhibition of tumor angiogenesis has been extensively utilized in the treatment of metastatic colorectal cancer and renal cell carcinoma. Complete disruption of tumor angiogenesis results in hypoxia which promotes tumor ... -
Immunohistochemical Expression of Insulin-Like Growth Factor-1, Transforming Growth Factor-Beta1, and Vascular Endothelial Growth Factor In Parathyroid Adenoma and Hyperplasia
(Medknow Publications & Media Pvt Ltd, 2014)Background: Insulin-like growth factor (IGF), transforming growth factor-beta1 (TGF-beta 1), and vascular endothelial growth factor (VEGF) are commonly studied growth factors, but little data are available on the ... -
Impact Of Acetylsalicylic Acid On The Clinicopathological Characteristics And Prognosis Of Patients With Invasive Breast Cancer
(Karger, 2014)Background: The impact of acetylsalicylic acid (ASA) on the clinicopathological characteristics of breast cancer has not yet been elucidated in detail; we therefore aimed to investigate the effects of ASA on the ... -
Impact Of Adjuvant Chemoradiotherapy For Rectal Cancer On The Long-Term Quality Of Life And Late Side Effects: A Multicentric Clinical Evaluation By The Turkish Oncology Group
(Asian Pacific Organization Cancer Prevention, 2012)Aim: Although preoperative chemoradiatherapy (CRT) has proven its benefits in terms of decreased toxicity, there is still a considerable amount of cases that do not receive postoperative CRT. Oncologists at different ... -
Inhibition of Serum and Glucocortıcoıd Inducible Kinase 1 (Sgk1) in Triple Negative Breast Cancer
(Kanser Enstitüsü, 2018-07-18)Glucocorticoid receptor overexpression leads to poor prognosis in breast cancer, particularly in triple negative phenotype. This poor prognosis has been shown to be due to the activation of SGK1 (serum and glucocorticoid ... -
Interactıon Mechanısms Between Small Cell Lung Cancer Cells And T Lymphocytes
(Kanser Enstitüsü, 2019-08)Tumors are capable of reshaping their microenvironment to escape from immune destruction. For this purpose, tumor cells initiate an immune regulatory program that is typically used by the normal cells to mitigate ... -
INVESTIGATION OF BIOMARKER POTENTIAL OF FGF RECEPTOR IN BREAST CANCER MODELS
(Kanser Enstitüsü, 2024)Breast cancer is a molecularly heterogeneous disease in which prognosis can be significantly improved through biomarker-driven targeted therapies. The aberration of fibroblast growth factor receptor (FGFR) signaling has ... -
Investigation of Lung Cancer Cell Culture Supernatants Activated with Tlr Agonists Effect on Macrophage Polarization
(Kanser Enstitüsü, 2018)It is well known that inflammation is involved in the development of lung cancer. Macrophages in the tumor microenvironment are the anti-inflammatory M2 type and anti-tumor type M1. Inflammatory cytokines, such as IL-1β, ... -
Is Plasma Caveolin-1 Level a Prognostic Biomarker in Metastatic Pancreatic Cancer?
(Wolters Kluwer - Medknow, 2017)Background/Aims: To evaluate the prognostic significance of plasma caveolin (CAV)-1 and its association with survival and treatment response rates in metastatic pancreatic cancer (MPC). Patients and Methods: Plasma samples ...