Bölüm "Temel Onkoloji" Kanser Enstitüsü için listeleme
Toplam kayıt 63, listelenen: 21-40
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Impact Of Acetylsalicylic Acid On The Clinicopathological Characteristics And Prognosis Of Patients With Invasive Breast Cancer
(Karger, 2014)Background: The impact of acetylsalicylic acid (ASA) on the clinicopathological characteristics of breast cancer has not yet been elucidated in detail; we therefore aimed to investigate the effects of ASA on the ... -
Impact Of Adjuvant Chemoradiotherapy For Rectal Cancer On The Long-Term Quality Of Life And Late Side Effects: A Multicentric Clinical Evaluation By The Turkish Oncology Group
(Asian Pacific Organization Cancer Prevention, 2012)Aim: Although preoperative chemoradiatherapy (CRT) has proven its benefits in terms of decreased toxicity, there is still a considerable amount of cases that do not receive postoperative CRT. Oncologists at different ... -
Inhibition of Serum and Glucocortıcoıd Inducible Kinase 1 (Sgk1) in Triple Negative Breast Cancer
(Kanser Enstitüsü, 2018-07-18)Glucocorticoid receptor overexpression leads to poor prognosis in breast cancer, particularly in triple negative phenotype. This poor prognosis has been shown to be due to the activation of SGK1 (serum and glucocorticoid ... -
Interactıon Mechanısms Between Small Cell Lung Cancer Cells And T Lymphocytes
(Kanser Enstitüsü, 2019-08)Tumors are capable of reshaping their microenvironment to escape from immune destruction. For this purpose, tumor cells initiate an immune regulatory program that is typically used by the normal cells to mitigate ... -
INVESTIGATION OF BIOMARKER POTENTIAL OF FGF RECEPTOR IN BREAST CANCER MODELS
(Kanser Enstitüsü, 2024)Breast cancer is a molecularly heterogeneous disease in which prognosis can be significantly improved through biomarker-driven targeted therapies. The aberration of fibroblast growth factor receptor (FGFR) signaling has ... -
Investigation of Lung Cancer Cell Culture Supernatants Activated with Tlr Agonists Effect on Macrophage Polarization
(Kanser Enstitüsü, 2018)It is well known that inflammation is involved in the development of lung cancer. Macrophages in the tumor microenvironment are the anti-inflammatory M2 type and anti-tumor type M1. Inflammatory cytokines, such as IL-1β, ... -
Is Plasma Caveolin-1 Level a Prognostic Biomarker in Metastatic Pancreatic Cancer?
(Wolters Kluwer - Medknow, 2017)Background/Aims: To evaluate the prognostic significance of plasma caveolin (CAV)-1 and its association with survival and treatment response rates in metastatic pancreatic cancer (MPC). Patients and Methods: Plasma samples ... -
İnsan Makrofajlarında Nitrik Oksit Sentaz 2 (Nos2) İfade ve Aktivitesinin Bazal Benzeri Meme Kanseri Hücrelerinden Üretilen Faktörler Varlığında İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Macrophages are the leading cells of innate immunity in the immune response against pathogens and are involved in the regulation of adaptive immune responses. Macrophages with microbicidal properties promote the proinflammatory ... -
Kolorektal Kanserlerde Th17 İlişkili IL-17, IL-21 ve IL-22 Sitokinlerinin Ekspresyon Düzeylerinin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Immune system cells and released cytokines in tumor microenvironment have a very important role in cancer prognosis. Also, T-helper 17 (Th17) cells have been frequently found in many tumors microenvironment and their effects ... -
Küçük Hücreli Dışı Akciğer Kanserinde Serum ve Glukokortikoid ile İndüklenebilen Kinaz 1 (SGK-1) İnhibisyonunun Epidermal Büyüme Faktörü Reseptörü (EGFR) Aracılı Sinyal Yolağı Üzerindeki Etkisi
(Kanser Enstitüsü, 2018)Oncogenic activation of epidermal growth factor receptor (EGFR) signaling exists in non-small cell lung cancer (NSCLC). Increased expression of Serum and Glucocorticoid Inducible Kinase 1 (SGK-1) in NSCLC cells was found ... -
Lack of Any Relationship Between Abo and Rh Blood Groups and Clinicopathological Features in Patients with Gastrointestinal Stromal Tumors
(Asian Pacific Organization Cancer Prevention, 2012)Background: An association between the ABO blood group and the risk of certain malignancies, including pancreatic and gastric cancer, has been reported previously. However, it is unclear whether this association is valid ... -
Lack of Association Between the Mthfr C677T Polymorphism and Lung Cancer in a Turkish Population
(Asian Pacific Organization Cancer Prevention, 2014)Background: In this case-control study, we aimed to investigate the relationship between the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials and Methods: Total 200 individuals ... -
Lack of Relationships Between Fgf19 Staining Pattern, Lymph Node Metastasis and Locally Invasive Characteristics of the Tumor in Colorectal Cancers
(Asian Pacific Organization Cancer Prevention, 2013)Introduction: Colorectal cancers are in the top of the cancer-related causes of death in the world and lymph node metastasis is accepted as the primary prognostic factor. In this study, correlations of FGF19 staining pattern ... -
Laryngeal Involvement of Rhabdomyosarcoma in an Adult
(BioMed Central, 2003)Background Although initial presentation of sarcomas in the head and neck region is relatively common, involvements of the larynx by rhabdomyosarcoma either primary or metastatic have been reported rarely. Case report A ... -
Long-Term Survival of Patients with Cll After Allogeneic Transplantation: A Report from the European Society for Blood and Marrow Transplantation
(Macmillan Publishers Limited, 2017)Even with the availability of targeted drugs, allogeneic hematopoietic cell transplantation (allo-HCT) is the only therapy with curative potential for patients with CLL. Cure can be assessed by comparing long-term survival ... -
Lung Cancer in Women: A Single Institution Experience with 50 Patients
(Asian Pacific Organization Cancer Prevention, 2014)Background: Lung cancer is the most common cause of cancer-related death worldwide. The incidence of lung cancer is aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate the clinical, ... -
Lung Cancer Screening: A Comprehensive Review of the Literature with Detailed Data
(Akad Doktorlar Yayınevi, 2014)Lung cancer still has a big proportion of cancer related deaths inspite of improvements in chemotherapeutic and surgical treatment approaches. It has a strong relationship with tobacco comsumption so that it can be regard ... -
Meme Kanseri Hücreleri Tarafından Üretilen Fibronektinin Miyeloid Hücre Karakteri Üzerine Etkisi
(Kanser Enstitüsü, 2019)Basal-like breast cancer (BLBC) possess high capacity to regulate inflammation and identified with high-level myeloid cell infiltration. Extracellular matrix components produced by tumor cells, e.g. fibronectin (FN), can ... -
Meme Kanserinde, Il-1β ile Tetiklenen Epitelyal Mezenkimal Dönüşümde Hücre İskeleti Dinamiklerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03)The presence of interleukin (IL)-1β, a proinflammatory cytokine, has been demonstrated in the breast cancer microenvironment. IL-1β supports cell survival, proliferation, adhesion, invasion, and migration mechanisms. It ... -
Meme Kanserinde, Normal Fibroblastlar ve Kanserle İlişkili Fibroblastların Monosit Çağrılması, Makrofaj Polarizasyonu ve İnvazyona Etkisi
(Kanser Enstitüsü, 2018)GÖK YAVUZ B., The Effect of Cancer Associated Fibroblasts and Normal Fibroblasts on Monocyte Recruitment, Macrophage Polarization and Invasion in Breast Cancer. Hacettepe University Institute of Health Sciences Ph.D Thesis ...