Browsing Fen Bilimleri Enstitüsü by Issue Date
Now showing items 81-100 of 155
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İçeceklerde Bulunan Amaranth Tayinine Yönelik Sensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-06)Within the scope of the study, an Amaranth imprinted surface plasmon resonance (SPR) sensor was prepared for the determination of Amaranth, an azo group food dye used in beverages and various food products and reported to ... -
Konjenital Septal Defektlerin Onarımına Yönelik Perikard Bazlı Rejeneratif Kardiyak Yamaların Doku Mühendisliği Yöntemi ile Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-06)Cardiac patch has been used in the treatment of congenital heart disease and myocardial infarction (MI) while an ideal cardiac patch has not been developed yet. This study aimed to engineer regenerative cardiac patches by ... -
Development of Jak1 Sirna Medıated Nanotherapeutıcs for Non-Melanoma Skın Cancer Therapy
(Fen Bilimleri Enstitüsü, 2021-06)Non-melanoma skin cancer is one of the most common cancers with still no effective treatment. Due to the side effects observed after long and high dose treatments and acquired resistance to the chemotherapy drugs, different ... -
MOLEKÜLER BASKILANMIŞ KRİYOJEL DİSKLERDEN KURKUMİNİN KONTROLLÜ SALIMI
(Fen Bilimleri Enstitüsü, 2021-07)In the drug research area, the way these drugs are administered to patients is as important as developing new molecules for the treatment of diseases. In recent years, controlled drug release systems have been developed ... -
Alt-Birim Protein Antijenlerinin İmmunojenitesini Artırmak Amacıyla Yeni Adjuvant/Taşıyıcı Sistemlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-07-22)Infectious diseases encompass 25% of deaths in the world per year. The most effective approach in preventing deaths is vaccination. However, at present, the availability of vaccines for many infectious diseases is still ... -
Trombosit Aktivasyonu İçin Alternatif Mekanik Yöntemlerin Belirlenmesi ve Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-12)Platelets are blood cells involved in clot formation, wound healing, and tissue regeneration. By enriching the blood plasma with various separation methods, platelet-rich plasma (PRP) is obtained. The effectiveness of PRP ... -
Fenilketonüri Hastalığının Erken Teşhisi ve Takibi için Disk Tabanlı Hasta Başı Tanı Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-12)Phenylketonuria (PKU) is an autosomal recessive metabolic disease due to dysfunction of phenylalanine hydroxylase (PAH) enzyme, which converts phenylalanine (Phe) amino acid to tyrosine amino acid. Phe amino acid and ... -
Kurkumin Tayinine Yönelik Yüzey Plazmon Rezonans Temelli Nanosensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2021-12)Herbal ingredients are among the most used products in alternative and complementary medicine. Curcumin, which is obtained from Curcuma longa plant known as Indian saffron or turmeric, has become quite popular in recent ... -
Aptamer Temelli Afinite Kromatografisiyle Protein C Saflaştırılmasının Araştırılması
(Fen Bilimleri Enstitüsü, 2021-12-30)Protein C (PC) is a vitamin K-dependent plasma protein. Activated Protein C (APC) is a glycoprotein derived from protein C. It is formed by cleavage of an activation peptide by the thrombin-linked thrombomodulin (T-TM) ... -
Konkanavalin A Baskılanmış Yüzey Plazmon Rezonans Temelli Biyosensörün Hazırlanması
(Fen Bilimleri Enstitüsü, 2022)Within the scope of this thesis, a Concanavalin A imprinted surface plasmon resonance (SPR) biosensor was prepared for the determination of Concanavalin A. At the beginning, the surface of the SPR biosensor chip was modified ... -
Graftıng Of Polystyrene To Poly(Ethylenealt- Tetrafluoroethylene) (Etfe) Fılms By Controlled Raft Polymerızatıon In The Presence Of A Crosslınkıng Agent
(Fen Bilimleri Enstitüsü, 2022)Controlling the molecular weights and distributions of polymers is not possible in syntheses carried out by conventional Free Radical Polymerization (FRP). This hinders the widespread use of FRP techniques in the synthesis ... -
Nanotopografik Fiber Matrikslerin Doku İskelesi Olarak Üretimi ve İn-Vitro Etkinliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2022)This study was funded by Hacettepe University Scientific Research Projects Coordination Unit (BAP) graduate project entitled "Production Of Nanotopographic Fiber Matrices As Tissue Scaffold And Investigation Of Their ... -
Fotovoltaik Uygulamalar için CZTS (Cu2SnZnS4) İnce Filmlerin Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022)Today, thin-film-based photovoltaic (PV) structures attract attention in the search for alternatives to Si-based solar cells. Among the thin films, the Cu2ZnSnS4 (CZTS) compound is the most remarkable with its optical and ... -
Pamuklu Kumaş Üzerinde Yıkanmış Kan Lekesinin Raman Spektroskopi ve Kemometri ile Tespiti
(Fen Bilimleri Enstitüsü, 2022)Bloodstains are abundant biological fluids that are encountered in crime scenes. Precise bloodstain detection on the “proof” has vitally importance for ongoing or post-commital stages. The criminal inclined to dispose the ... -
M13mp18 İskele İpliğinden DNA Origami Nanodemetlerin Geliştirilmesi Ve İlaç Taşıyıcı Olarak Kullanımının İncelenmesi
(Fen Bilimleri Enstitüsü, 2022)Currently, in nanotechnology and biomedical field DNA nanotechnology is more and more used instead of conventional methods and important studies are carried out. Complementary base pairing of DNA has taken it to the next ... -
Spermatogenezin Tasarlanmış Farklı Üç Boyutlu Fare Epididimal Beyaz Yağ Dokusu - Testis Kokültüründe Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2022)Gonadotoxic treatments in childhood cancer patients damage the testicular germ cells and microenvironment, causing 46% of the patients to become infertile. Air-liquid interphase (ALI) and U-plate (UP) techniques are ... -
Arsenik ve Selenyum İyonlarının Adsorpsiyonunda Anyon Değiştirici Polimerik Adsorbentlerin Kullanımı
(Fen Bilimleri Enstitüsü, 2022)In this thesis, polystyrene modified with N,N-dimethyleneethylenediamine molecules (DMEDA-m-CMS) with anion exchange properties was investigated as an effective adsorbent for As(V) and Se(VI) ions from the aqueous system. ... -
Moleküler Dinamik Simülasyonlarında Dissipatif Kuvvetin Yaptığı İşin Hesaplanması
(Fen Bilimleri Enstitüsü, 2022)Although it is quite difficult to model friction on the atomic scale, recent theoretical and experimental techniques have enabled the study of friction at atomic scales, which could not be studied with conventional models ... -
Endokrin Bozucu Hormonlara Özgü Gravimetrik Nanosensörün Hazırlanması ve Moleküler Modellenmesi
(Fen Bilimleri Enstitüsü, 2022)Natural estrogenic hormones are frequently used as birth control drugs in hormonal treatments for women and as growth precursors of farm animals in veterinary practice. These components threaten human health and wildlife ... -
Taşınabilir Raman Spektrometresi ile Patlayıcı Öncülü Olarak Toprakta Amonyum Nitrat Tayini; Kantitatif Analiz için Zemin Düzeltme Yöntemi Uygulaması
(Fen Bilimleri Enstitüsü, 2022)In simple terms, explosives can be defined as substances that are capable of producing an explosion and produce a large volume of expanding gas in a very short period, creating a strong destructive impact on the target. ...